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The IUPHAR Guide to IMMUNOPHARMACOLOGY ligand list

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GtoImmuPdb ligands only: Ligands which are currently, or have been in the past, approved for human clinical use by a regulatory agency.
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Ligand name ID Synonyms
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abatacept Approved drug Immunopharmacology Ligand 6891 BMS-188667, CTLA4-IgG4m, Orencia®, RG-1046, RG-2077
abrocitinib Approved drug PDB Ligand Immunopharmacology Ligand 9991 Cibinqo®, compound 25 [PMID: 29298069], PF-04965842, PF04965842
acalabrutinib Approved drug Immunopharmacology Ligand 8912 ACP-196, Calquence®, Example 6 [US20140155385 A1]
ACTH  {Sp: Human} Approved drug Immunopharmacology Ligand 3633 Acthar®, adrenocorticotropic hormone (1-39), corticotropin
adalimumab Approved drug Immunopharmacology Ligand 4860 D2E7, Humira®
(-)-adrenaline Approved drug PDB Ligand Immunopharmacology Ligand 479 adrenalin, Auvi-Q®, Epipen®, l-adrenaline, L-epinephrine, levoepinephrine
alcaftadine Approved drug Immunopharmacology Ligand 7587 Lastacaft®, R-89674
alefacept Approved drug Immunopharmacology Ligand 6787 Amevive®, BG 9273, BG 9712, BG-9273, BG-9712, Lfa3Tip
alemtuzumab Approved drug Immunopharmacology Ligand 6770 campath 1H, Campath®, campath-1H, Lemtrada®
alimemazine Approved drug Immunopharmacology Ligand 7237 Nedeltran®, trimeprazine
amcinonide Approved drug Immunopharmacology Ligand 7060 CL-34699, Cyclocort®
amlexanox Approved drug PDB Ligand Immunopharmacology Ligand 7113 AA-673, Amlexanox®, Aphthasol®, CHX-3673
anakinra Approved drug Immunopharmacology Ligand 6972 antril, Kineret®
anifrolumab Approved drug Immunopharmacology Ligand 8258 anifrolumab-fnia, MDX-1333, MEDI-546, Saphnelo®
apremilast Approved drug PDB Ligand Immunopharmacology Ligand 7372 CC-10004, Otezla®
arformoterol Approved drug PDB Ligand Immunopharmacology Ligand 7479 Brovana®, YM-08316
aspirin Approved drug PDB Ligand Immunopharmacology Ligand 4139 Acetophen®, acetylsalicylic acid, Aspirin®
atezolizumab Approved drug Immunopharmacology Ligand 7990 MPDL3280A, Tecentriq®
atracurium Approved drug Immunopharmacology Ligand 9537 atracurium besilate, atracurium dibesylate, BW 33A, Tracrium®
auranofin Approved drug Immunopharmacology Ligand 6306 Ridaura®, SK&F-39162, SK-39162
avacopan Approved drug PDB Ligand Immunopharmacology Ligand 9450 CCX-168, CCX168, Tavneos®
avapritinib Approved drug Immunopharmacology Ligand 10368 Ayvakit®, Ayvakyt®, BLU-285, BLU285
avelumab Approved drug Immunopharmacology Ligand 8735 Bavencio®, MSB-0010718C, MSB0010718C
azacitidine Approved drug PDB Ligand Immunopharmacology Ligand 6796 5-AZAC, 5-azacytidine, ladakamycin, Onureg®, Onureg® (CC-486; oral azacitidine), U-18496, Vidaza®
azatadine Approved drug Immunopharmacology Ligand 7119 Optimine®, SCH-10649
azathioprine Approved drug Immunopharmacology Ligand 7120 Azasan®, BW-57-322, Imuran®, Jayempi®
azelaic acid Approved drug PDB Ligand Immunopharmacology Ligand 7484 Azelex®, Finacea®, ZK-62498
azithromycin Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6510
 
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baricitinib Approved drug PDB Ligand Immunopharmacology Ligand 7792 INCB-028050, INCB028050, LY-3009104, LY3009104, Olumiant®
basiliximab Approved drug Immunopharmacology Ligand 6879 CHI-621, L04AC02, SDZ-CHI-621, Simulect®
beclometasone Approved drug PDB Ligand Immunopharmacology Ligand 7059 beclomethasone, SCH-18020W
beclometasone dipropionate Approved drug Immunopharmacology Ligand 5894 beclomethasone dipropionate, Beconase®, Qnasl®, Vancenase®
belantamab mafodotin Approved drug Immunopharmacology Ligand 11117 belamaf, belantamab mafodotin-blmf, Blenrep®, GSK-2857916, GSK2857916
belatacept Approved drug Immunopharmacology Ligand 6892 BMS-224818, LEA29Y, Nulojix®
belimumab Approved drug Immunopharmacology Ligand 6887 Benlysta®, hBlySmAb-1.1, LimphoStat-B, lymphostat-B
belumosudil Approved drug Immunopharmacology Ligand 9558 KD-025, KD025, Rezurock®, SLx 2119, SLx2119
benralizumab Approved drug Immunopharmacology Ligand 7674 BIW-8405, Fasenra®, KHK4563, MEDI-563
betamethasone Approved drug Immunopharmacology Ligand 7061 SCH-4831
bimekizumab Approved drug Immunopharmacology Ligand 9411 Bimzelx®, CA028_0496, CDP4940, gL7gH9, UCB-4940, UCB4940, Zu-G1
blinatumomab Approved drug Immunopharmacology Ligand 7384 Blincyto®, bscCD19xCD3, MEDI-538, MT-103, MT103
bortezomib Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6391 peptide boronate, PS-341, Velcade®
bosutinib Approved drug PDB Ligand Immunopharmacology Ligand 5710 Bosulif®, SK 606, SK-606, SKI 606
brentuximab vedotin Approved drug Immunopharmacology Ligand 6772 Adcetris®, anti-CD30 ADC SGN-35, SGN 35
brimonidine Approved drug PDB Ligand Immunopharmacology Ligand 520 Alphagan®, Lumify®, Mirvaso®, UK14,304, UK14304
brodalumab Approved drug Immunopharmacology Ligand 7540 AMG-827, AMG827, Kyntheum®, Lumicef®, Siliq®
bromfenac Approved drug PDB Ligand Immunopharmacology Ligand 7131 AHR-10282B, Bromday®, Prolensa®, Xibrom®
budesonide Approved drug Immunopharmacology Ligand 7434 Entocort®, Eohilia® (budesonide oral suspension), Jorveza®, Pulmicort®, S-1320, Uceris®
 
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camrelizumab Approved drug Immunopharmacology Ligand 9758 INCSHR1210, SHR-1210
canakinumab Approved drug Immunopharmacology Ligand 6773 ACZ 885, ACZ885, Ilaris®
carotegrast methyl Approved drug Immunopharmacology Ligand 10510 AJM-300, AJM300, Carogra®
carprofen Approved drug Immunopharmacology Ligand 7141 Ro-205720000
celecoxib Approved drug PDB Ligand Immunopharmacology Ligand 2892 Celecox®, Elyxyb® (DFN-15; oral solution), Onsenal®, SC-58635, SC58635
cemiplimab Approved drug Immunopharmacology Ligand 10090 cemiplimab-rwlc, Libtayo®, REGN-2810, REGN2810, SAR-439684, SAR439684
certolizumab pegol Approved drug Immunopharmacology Ligand 6774 CDP870, Cimzia®, PHA 738144
cetirizine Approved drug Immunopharmacology Ligand 1222 Reactine®, Zyrtec®
cetrorelix Approved drug Immunopharmacology Ligand 1190 Cetrotide®, SB-075
chloroquine Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 5535 Aralen®, chloraquine, Malaquin®
ciclesonide Approved drug Immunopharmacology Ligand 7469 Alvesco®, Omnaris®, RPR-251526
clemastine Approved drug Immunopharmacology Ligand 6063 HS-592, meclastin, Tavegil®, Tavist®
clobetasol propionate Approved drug PDB Ligand Immunopharmacology Ligand 7062 CCI-4725, Clobex®, Dermovate®, GR 2/925, Temovate®
clobetasone Approved drug Immunopharmacology Ligand 9088 Eumovate®
clodronic acid Approved drug Immunopharmacology Ligand 9605 Bonefos®, Clasteon ®, clodronate, Loron®
clofazimine Approved drug Immunopharmacology Ligand 9184 Lamprene®
colchicine Approved drug PDB Ligand Immunopharmacology Ligand 2367 Colcrys®, methoxylated analogue of XD1, XD25
corticotropin zinc hydroxide Approved drug Immunopharmacology Ligand 6967
cortisol Approved drug PDB Ligand Immunopharmacology Ligand 2868 Acticort®, Efmody®, Plenadren®
crisaborole Approved drug Immunopharmacology Ligand 9151 AN 2728, AN2728, compound 5b [PMID: 19303290], Eucrisa®, Staquis®
crizotinib Approved drug PDB Ligand Immunopharmacology Ligand 4903 (R)-crizotinib, PF 2341066, PF-02341066, PF-2341066, PF2341066, Xalkori®
cromoglicic acid Approved drug Immunopharmacology Ligand 7608 cromoglycate, cromolyn, cromolyn sodium, FPL-670, Intal®, Opticrom®, sodium cromoglicate
cyclosporin A Approved drug Immunopharmacology Ligand 1024 ciclosporin, cyclosporine, cyclosporine A, Ikervis® (opthalmic solution), Neoral®, Sandimmun®, Verkazia® (opthalmic solution)
 
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daclizumab Approved drug Immunopharmacology Ligand 6880 L04AC01, RO-24-7375, Ro-247375, Zenapax®
daratumumab Approved drug Immunopharmacology Ligand 7395 3003-005, Darzalex®, HuMax-CD38, JNJ-54767414
dasatinib Approved drug PDB Ligand Immunopharmacology Ligand 5678 BMS 345825, BMS 354825, BMS 35482513, Sprycel®
deflazacort Approved drug Immunopharmacology Ligand 9477 Emflaza®, MDL 458
delgocitinib Approved drug PDB Ligand Immunopharmacology Ligand 9619 Corectim®, ent-60, JTE-052, JTE052
denileukin diftitox Approved drug Immunopharmacology Ligand 7044 DAB389 IL2, LY 335348, Ontak®
desloratadine Approved drug Immunopharmacology Ligand 7157 Clarinex®, SCH-34117
desonide Approved drug Immunopharmacology Ligand 7066 D-2083, Desowen®
desoximetasone Approved drug Immunopharmacology Ligand 7067 A-41-304, HOE-304, R-2113, Topicort®
deucravacitinib Approved drug Immunopharmacology Ligand 10432 BMS-986165, BMS986165, compound 11 [PMID: 31318208}, Sotyktu®, Tyk2-IN-4
dexamethasone Approved drug PDB Ligand Immunopharmacology Ligand 2768 Decadron®, desametasone, fluormethylprednisolone
diclofenac Approved drug PDB Ligand Immunopharmacology Ligand 2714 Cataflam®, CGP-45840B, GP-45840, Voltaren®, Voltarol®
difelikefalin Approved drug Immunopharmacology Ligand 9044 CR845, D-Phe-D-Phe-D-Leu-D-Lys-[γ-(4-N-piperidinyl)amino carboxylic acid], FE-202845, Kapruvia®, Korsuva®, SEQ ID NO: 2
diflorasone diacetate Approved drug Immunopharmacology Ligand 7068 Psorcon®, U-34865
diflunisal Approved drug PDB Ligand Immunopharmacology Ligand 7162 Dolobid®
difluprednate Approved drug Immunopharmacology Ligand 7474 DFBA, Durezol®, W-6309
dimethyl fumarate Approved drug PDB Ligand Immunopharmacology Ligand 7045 BG-12, BG00012, fumaric acid, Tecfidera®
dimetindene Approved drug Immunopharmacology Ligand 10101 (+/-)-dimethindene, dimethindene, dimethpyrindene, Fenistil®, Vibrocil®
diphenylpyraline Approved drug Immunopharmacology Ligand 7165 Hispril®
diroximel fumarate Approved drug Immunopharmacology Ligand 10525 ALKS-8700, ALKS8700, BIIB098, Vumerity®
dopamine Approved drug PDB Ligand Immunopharmacology Ligand 940 3-hydroxytyramine
doxycycline Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6464 BMY-28689, Monodox®, Vibramycin®
dupilumab Approved drug Immunopharmacology Ligand 7574 Dupixent®, REGN668, SAR231893
durvalumab Approved drug Immunopharmacology Ligand 7985 anti-B7H1 monoclonal antibody, Imfinzi®, MEDI-4736, MEDI4736
duvelisib Approved drug Immunopharmacology Ligand 7795 compound 4904 [Patent US8193182], Copiktra®, INK-1197, IPI-145
dyphylline Approved drug Immunopharmacology Ligand 7070 Dilor®
 
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ecallantide Approved drug Immunopharmacology Ligand 6955 DX-88, FOV2302, Kalbitor®
eculizumab Approved drug Immunopharmacology Ligand 6884 h5G1.1, h5G1.1VHC, Soliris®
efalizumab Approved drug Immunopharmacology Ligand 6593 anti alphaL integrin, antiCD11 alpha, hu1124, Raptiva®
efgartigimod alfa Approved drug Immunopharmacology Ligand 9777 ARGX-113, efgartigimod alfa-fcab, Vyvgart®
elotuzumab Approved drug Immunopharmacology Ligand 8361 BMS-901608, Empliciti®, HuLuc63
emapalumab Approved drug Immunopharmacology Ligand 9295 emapalumab-lzsg, Gamifant®, NI-0501, NI0501
envafolimab Approved drug Immunopharmacology Ligand 10492 Envida®, KN-035, KN035
epinastine Approved drug Immunopharmacology Ligand 7176 Elestat®, epinastine hydrochloride
esflurbiprofen Approved drug PDB Ligand Immunopharmacology Ligand 9420 (S)-flurbiprofen, BTS-24332, SFPP, TT-063
etanercept Approved drug Immunopharmacology Ligand 6789 Enbrel®, Rhu Tnfr:Fc, TNFR-Fc, TNR 001
etodolac Approved drug Immunopharmacology Ligand 7185 AY-24236, Lodine®
etoricoxib Approved drug PDB Ligand Immunopharmacology Ligand 2896 Arcoxia®, MK 0663, MK-0663, MK0663
everolimus Approved drug Immunopharmacology Ligand 5889 Afinitor®, Certican®, RAD-001, RAD001, rapamycin, 42-O-(2-hydroxyethyl)-, Zortress®
 
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fenoprofen Approved drug Immunopharmacology Ligand 4820 fenoprofen calcium, Nalfon®
fexofenadine Approved drug Immunopharmacology Ligand 4819 Allegra®, fexofenadine HCl
filgotinib Approved drug PDB Ligand Immunopharmacology Ligand 7913 GLPG-0634, GLPG0634, Jyseleca®
filgrastim Approved drug Immunopharmacology Ligand 6968 Filcad®, Imumax ®, R-METHUG-CSF
fingolimod Approved drug Immunopharmacology Ligand 2407 FTY-720, FTY720, Gilenya®
fludroxycortide Approved drug Immunopharmacology Ligand 7606 Cordran®, flurandrenolide, flurandrenolone, Haelan®
flufenamic acid Approved drug PDB Ligand Immunopharmacology Ligand 2447
flumethasone pivalate Approved drug Immunopharmacology Ligand 7075 Locorten®
flunisolide Approved drug Immunopharmacology Ligand 7076 AeroBid®, RS-3999
fluocinolone acetonide Approved drug Immunopharmacology Ligand 7077 Capex®, Iluvien®, Synalar®
fluocinonide Approved drug Immunopharmacology Ligand 7078 Fluonex®, Lidex®
fluorometholone Approved drug Immunopharmacology Ligand 7079 Flarex®, FML®
flurbiprofen Approved drug Immunopharmacology Ligand 4194 Ansaid®, Froben®
fluticasone Approved drug Immunopharmacology Ligand 6699 Advair®, Avamys®, Flovent HFA®, Veramyst®
fluticasone furoate Approved drug PDB Ligand Immunopharmacology Ligand 10892 Arnuity Ellipta, Avamys, FF, Flonase Sensimist, Veramyst
fluticasone propionate Approved drug Immunopharmacology Ligand 7080 Advair Diskus®, ArmonAir RespiClickTM, CCI-18781, Flovent®
fluvoxamine Approved drug PDB Ligand Immunopharmacology Ligand 7189 Luvox®, U-23000
formoterol Approved drug Immunopharmacology Ligand 3465 BD-40A, CGP-25827A, Foradil®, Oxeze/Oxis®, YM-08316
fostamatinib Approved drug PDB Ligand Immunopharmacology Ligand 7796 R 788, R-788, R7935788, Tavalisse®, Tavlesse®
 
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gabapentin Approved drug PDB Ligand Immunopharmacology Ligand 5483 CI 945, Go 3450, GOE 2450, GOE 3450, Neurontin®
galcanezumab Approved drug Immunopharmacology Ligand 8967 clone III, Emgality®, galcanezumab-gnlm, LY-2951742, LY2951742
G-CSF  {Sp: Human} Approved drug Immunopharmacology Ligand 4934 Granocyte®
gefapixant Approved drug PDB Ligand Immunopharmacology Ligand 9540 AF-219, AF219, Lyfnua®, MK7264, MK‐7264
gemtuzumab ozogamicin Approved drug Immunopharmacology Ligand 6775 CDP 771, CMA 676, hP67.6-calicheamicin, Mylotarg®, WAY-CMA 676
glibenclamide Approved drug PDB Ligand Immunopharmacology Ligand 2414 Amglidia®, Diabeta®, glyburide, Glynase®
glycopyrrolate Approved drug Immunopharmacology Ligand 7459 AHR-504, Qbrexza® (glycopyrronium cloth), Robinul®, Seebri Neohaler®, Tovanor Breezhaler®
golimumab Approved drug Immunopharmacology Ligand 6776 CNTO-148, CNTO148, Simponi®
guselkumab Approved drug Immunopharmacology Ligand 7998 CNTO-1959, Tremfya®
 
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hydroxychloroquine Approved drug Immunopharmacology Ligand Antimalarial Ligand 7198 Dolquine®, Plaquenil®
hydroxyzine Approved drug Immunopharmacology Ligand 7199 Atarax®, hydroxyzine hydrochloride, hydroxyzine pamoate, Vistaril®
 
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ibalizumab Approved drug Immunopharmacology Ligand 10208 Hu5A8, ibalizumab-uiyk, TMB-355, TMB355, TNX-355, Trogarzo®
ibritumomab tiuxetan Approved drug Immunopharmacology Ligand 6777 IDEC-2B8, IDEC-Y2B8-yttrium ibritumomab tiuxetan, NSC-715848, Zevalin®
ibrutinib Approved drug PDB Ligand Immunopharmacology Ligand 6912 Imbruvica®, PCI-32765
ibudilast Approved drug PDB Ligand Immunopharmacology Ligand 7399 AV-411, KC-404, Ketas®, MN-166
ibuprofen Approved drug Immunopharmacology Ligand 2713 Advil®, Brufen®, ibuprofen lysine, ibuprofen sodium, Motrin®, Nurofen®, U-18573
icatibant Approved drug Immunopharmacology Ligand 667 D-Arg-[Hyp3,Thi5,D-Tic7,Oic8]BK, Firazyr®, HOE 140, HOE140
idelalisib Approved drug PDB Ligand Immunopharmacology Ligand 6741 CAL-101/CAL101, GS-1101, Zydelig®
IFN-α2  {Sp: Human} Approved drug Immunopharmacology Ligand 4960 IFN-alpha-2, interferon alpha-2, Roferon A®
IFN-γ  {Sp: Human} Approved drug Immunopharmacology Ligand 4968 Actimmune®, immune interferon, interferon gamma
IFN-β1b (recombinant human) Approved drug Immunopharmacology Ligand 8340 Betaferon®, Betaseron®, Extavia®, IFNb1b
iguratimod Approved drug Immunopharmacology Ligand 9736 Careram®, Iremod, Kolbet®, T-614
IL-2  {Sp: Human} Approved drug Immunopharmacology Ligand 4985 aldesleukin, interleukin-2, Proleukin®
iloprost Approved drug Immunopharmacology Ligand 1895 Ventavis®
imatinib Approved drug PDB Ligand Immunopharmacology Ligand 5687 CGP 57148, Gleevec®, Glivec®, STI571
imiquimod Approved drug PDB Ligand Immunopharmacology Ligand 5003 Aldara®, R837, S-26308, Zyclara®
indacaterol Approved drug Immunopharmacology Ligand 7455 Arcapta Neohaler®, Onbrez®, QAB-149, QAB149
indomethacin Approved drug PDB Ligand Immunopharmacology Ligand 1909 Indocid®, Indocin®
infliximab Approved drug Immunopharmacology Ligand 5004 cA2, Inflectra®, Remicade®, Remsima®, SB2, TA-650
inotuzumab ozogamicin Approved drug Immunopharmacology Ligand 8266 Besponsa®, CMC-544
ipilimumab Approved drug Immunopharmacology Ligand 6888 MDX-010, MDX-101, MDX-CTLA-4, Yervoy®
ipratropium Approved drug Immunopharmacology Ligand 325 Atrovent®, Ipraxa®
isoetarine Approved drug Immunopharmacology Ligand 7205 Bronkometer®, Bronkosol®, WIN-3406
itolizumab Approved drug Immunopharmacology Ligand 9421 Alzumab®, T1h
ixekizumab Approved drug Immunopharmacology Ligand 7541 LY-2439821, LY2439821, Taltz®
 
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ketoprofen Approved drug Immunopharmacology Ligand 4795 Actron®, Orudis®
ketorolac Approved drug Immunopharmacology Ligand 6661 Acular®, Toradol®
 
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leflunomide Approved drug Immunopharmacology Ligand 6825 Arabloc®, Arava®, HWA 486, HWA-486, lefunamide, SU-101
lenalidomide Approved drug Immunopharmacology Ligand 7331 CC-5013, CDC-501, Revlimid®
levosalbutamol Approved drug PDB Ligand Immunopharmacology Ligand 9816 (-)-albuterol, (-)-salbutamol, (R)-salbutamol, levalbuterol, Xopenex®
lifitegrast Approved drug Immunopharmacology Ligand 7533 compound 1g [PMID: 24900456], SAR 1118, SAR-1118, SAR-1118-023, Xiidra®
lodoxamide Approved drug Immunopharmacology Ligand 9743 Alomide®
loratadine Approved drug Immunopharmacology Ligand 7216 Claritin®, SCH-29851
loteprednol etabonate Approved drug Immunopharmacology Ligand 7085 HGP-1, Inveltys®, Lotemax®, P-5604
lovastatin Approved drug PDB Ligand Immunopharmacology Ligand 2739 (+)-mevinolin, 6α-methylcompactin, Mevacor®
lumiracoxib Approved drug PDB Ligand Immunopharmacology Ligand 2897 Prexige®
 
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maraviroc Approved drug Immunopharmacology Ligand 806 Celsentri®, Selzentry®, UK 427857, UK-427,857
meclofenamic acid Approved drug PDB Ligand Immunopharmacology Ligand 7219 CL-583, INF-4668, Meclomen®
medrysone Approved drug Immunopharmacology Ligand 7086 U-8471
mefenamic acid Approved drug PDB Ligand Immunopharmacology Ligand 2593 CI-473, CN-35355, INF-3355, Ponstan®, Ponstel®
melatonin Approved drug PDB Ligand Immunopharmacology Ligand 224 MLT, Circadin®
meloxicam Approved drug PDB Ligand Immunopharmacology Ligand 7220 Mobic®, UHAC-62XX
mepolizumab Approved drug Immunopharmacology Ligand 7685 Nucala®, SB-240563
mepyramine Approved drug Immunopharmacology Ligand 1227 Anthisan®, mepiramine, mepyramine maleate, pyrilamine, pyrilamine tannate, Pyrlex®
mesalazine Approved drug Immunopharmacology Ligand 2700 5-aminosalicylic acid, 5-ASA, mesalamine (USAN), Pentasa®
metformin Approved drug PDB Ligand Immunopharmacology Ligand 4779 Glucophage®, LA-6023
methacholine Approved drug Immunopharmacology Ligand 7438 methacholine bromide, Provocholine®
methimazole Approved drug PDB Ligand Immunopharmacology Ligand 6649 Tapazole®, Thiamazole®
methotrexate Approved drug PDB Ligand Immunopharmacology Ligand 4815 Abitrexate®, amethopterin, Nordimet®, Rasuvo®
methylprednisolone Approved drug Immunopharmacology Ligand 7088 Medrol®, U-67590A
midostaurin Approved drug PDB Ligand Immunopharmacology Ligand 5702 CGP 41231, CGP 41251, N-benzoylstaurosporine, PKC412, Rydapt®
mifepristone Approved drug PDB Ligand Immunopharmacology Ligand 2805 Mifeprex®, RU-486, RU486
miltefosine Approved drug Immunopharmacology Ligand 11355 D-18506, D18506, Impavido®, Miltex®, n-hexadecylphosphorylcholine
mizolastine Approved drug Immunopharmacology Ligand 10102 Mizollen®, MKC-431, MKC431, SL 85.0324, SL-850324, SL850324
mogamulizumab Approved drug Immunopharmacology Ligand 6477 KW-0761, mogamulizumab-kpkc, Poteligeo®
mometasone Approved drug Immunopharmacology Ligand 9029 Elocon® (topical), Nasonex®
montelukast Approved drug PDB Ligand Immunopharmacology Ligand 3340 Singulair®
moxetumomab pasudotox Approved drug Immunopharmacology Ligand 7675 CAT-8015, GCR-8015, HA22, Lumoxiti®, moxetumomab pasudotox-tdfk
muromonab-CD3 Approved drug Immunopharmacology Ligand 6889 L04AA02, OKT-3, Orthoclone Okt3®
mycophenolate mofetil Approved drug Immunopharmacology Ligand 6831 Cellcept®, RS-61443, RS-61443-190
 
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nabumetone Approved drug PDB Ligand Immunopharmacology Ligand 7245 BRL-14777, Relafen®
naproxen Approved drug PDB Ligand Immunopharmacology Ligand 5230 (S)-naproxen, Aleve®, Naprosy®
natalizumab Approved drug Immunopharmacology Ligand 6591 AN100226, anti-alpha4 integrin, anti-VLA4, Tysabri®
nedocromil Approved drug Immunopharmacology Ligand 7607 FPL-59002, nedocromil sodium, Rapitil®, Tilade®
nemolizumab Approved drug Immunopharmacology Ligand 8720 CD14152, CIM 331, CIM331, Mitchga®
niflumic acid Approved drug PDB Ligand Immunopharmacology Ligand 2439
nimesulide Approved drug PDB Ligand Immunopharmacology Ligand 7401 R-805
nivolumab Approved drug Immunopharmacology Ligand 7335 BMS-936558, MDX-1106, ONO-4538, Opdivo®
 
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obinutuzumab Approved drug Immunopharmacology Ligand 6941 GA-101, GA101, Gazyva®
ocrelizumab Approved drug Immunopharmacology Ligand 7580 2H7, Ocrevus®, PRO70769, RG1594
ofatumumab Approved drug Immunopharmacology Ligand 6778 Arzerra®, GSK 1841157, GSK1841157, humax-CD20, Kesimpta® (subcutaneous), OMB-157, OMB157
olodaterol Approved drug Immunopharmacology Ligand 7543 BI-1744, BI-1744-CL, Striverdi®
olopatadine Approved drug Immunopharmacology Ligand 7249 ALO-4943A, KW-4679, Opatanol®, Patanol®, Pazeo®
olverembatinib Approved drug Immunopharmacology Ligand 10630 compound 10a [PMID: 23301703], GZD-824, GZD824, HQP-1351, HQP1351
omalizumab Approved drug Immunopharmacology Ligand 6890 IGE25, olizumab, R03DX05, RG-3648, rhumab-E25, Xolair®
oprelvekin Approved drug Immunopharmacology Ligand 6971 Neumega®
orelabrutinib Approved drug Immunopharmacology Ligand 10629 example 3 [WO2015048662A2], ICP-022, ICP022
oxaprozin Approved drug Immunopharmacology Ligand 7252 Daypro®, WY-21743
ozagrel Approved drug Immunopharmacology Ligand 9866 Cataclot®, KCT-0809, OKY-046, Pulmoza®
ozanimod Approved drug PDB Ligand Immunopharmacology Ligand 8709 RPC-1063, RPC1063, Zeposia®
 
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parecoxib Approved drug PDB Ligand Immunopharmacology Ligand 2895 Dynastat®, SC-69124
pecazine Approved drug Immunopharmacology Ligand 9782 mepazine, nothiazine, Pacatal
peficitinib Approved drug Immunopharmacology Ligand 8315 ASP015K, JNJ-54781532
peginterferon alfa-2b Approved drug Immunopharmacology Ligand 7462 PegIntron®, Sylatron®
peginterferon beta-1a Approved drug Immunopharmacology Ligand 7637 interferon beta 1-alpha, PEG-INF-β-1a, Plegridy®
pembrolizumab Approved drug Immunopharmacology Ligand 7499 Keytruda®, lambrolizumab, MK-3475
penicillamine Approved drug PDB Ligand Immunopharmacology Ligand 7264 Cuprimine®
PGE2 Approved drug PDB Ligand Immunopharmacology Ligand 1883 Cervidil®, minprositin E2, minprostin E2, Propess®, prostaglandin E2
phenylbutazone Approved drug PDB Ligand Immunopharmacology Ligand 7270 Butazolidine®
pirfenidone Approved drug Immunopharmacology Ligand 7532 AMR-69, Esbriet®
piroxicam Approved drug Immunopharmacology Ligand 7273 CP-16171, Feldene®
plerixafor Approved drug Immunopharmacology Ligand 844 AMD 3100, AMD3100, bicyclam JM-2987, JM 3100, Mozobil®
polatuzumab vedotin Approved drug Immunopharmacology Ligand 8404 ACD79B-VCMMAE, polatuzumab vedotin-piiq, Polivy®, RG-7596, RG7596, RO5541077-000
polmacoxib Approved drug PDB Ligand Immunopharmacology Ligand 8316 Acelex® (S. Korea), CG-100649, CG100649
pomalidomide Approved drug Immunopharmacology Ligand 7348 CC-4047, IMID-3, Imnovid®, Pomalyst®
ponatinib Approved drug PDB Ligand Immunopharmacology Ligand 5890 AP24534, Iclusig®