fluocinolone acetonide   Click here for help

GtoPdb Ligand ID: 7077

Synonyms: Capex® | Iluvien® | Synalar®
Approved drug Immunopharmacology Ligand
fluocinolone acetonide is an approved drug (FDA (1963))
Compound class: Synthetic organic
Comment: Fluocinolone acetonide is a corticosteroid.
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 93.06
Molecular weight 452.2
XLogP 1.15
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES OCC(=O)C12OC(OC1CC1C2(C)CC(O)C2(C1CC(C1=CC(=O)C=CC21C)F)F)(C)C
Isomeric SMILES OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@]2([C@H]1C[C@@H](C1=CC(=O)C=C[C@]21C)F)F)(C)C
InChI InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1963))
International Nonproprietary Names Click here for help
INN number INN
1046 fluocinolone acetonide
Synonyms Click here for help
Capex® | Iluvien® | Synalar®
Database Links Click here for help
CAS Registry No. 67-73-2
DrugBank Ligand DB00591
DrugCentral Ligand 1204
GtoPdb PubChem SID 178103656
PubChem CID 6215
Search Google for chemical match using the InChIKey FEBLZLNTKCEFIT-VSXGLTOVSA-N
Search Google for chemicals with the same backbone FEBLZLNTKCEFIT
Search PubMed clinical trials fluocinolone acetonide
Search PubMed titles fluocinolone acetonide
Search PubMed titles/abstracts fluocinolone acetonide
UniChem Compound Search for chemical match using the InChIKey FEBLZLNTKCEFIT-VSXGLTOVSA-N
UniChem Connectivity Search for chemical match using the InChIKey FEBLZLNTKCEFIT-VSXGLTOVSA-N
Wikipedia Fluocinolone acetonide