procaterol [Ligand Id: 3464] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL160519 (Meptin, Procaterol)
  • β2-adrenoceptor/Beta-2 adrenergic receptor in Human [ChEMBL: CHEMBL210] [GtoPdb: 29] [UniProtKB: P07550]
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  • D2 receptor/Dopamine D2 receptor in Human [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
β2-adrenoceptor/Beta-2 adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL210] [GtoPdb: 29] [UniProtKB: P07550]
ChEMBL Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nM B 7.1 pKd 79.43 nM Kd Bioorg. Med. Chem. Lett. (2013) 23: 5376-5381 [PMID:23954364]
ChEMBL Displacement of [3H]CGP12177 from human beta2 receptor expressed in CHO cells B 7.48 pKi 33 nM Ki Bioorg. Med. Chem. (2016) 24: 2641-2653 [PMID:27132867]
GtoPdb - - 8.43 pEC50 - - - Br J Pharmacol (2010) 160: 1048-61 [PMID:20590599]
D2 receptor/Dopamine D2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416]
ChEMBL Displacement of [3H]spiperone from human D2S receptor expressed in CHO cells B 4.07 pKi 86000 nM Ki Bioorg. Med. Chem. (2016) 24: 2641-2653 [PMID:27132867]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]