Abrocitinib (PF-04965842) is an investigational JAK inhibitor [4
]. X-ray crystal structures of PF-04965842 bound to both JAK1 and JAK2 have been deposited with the Protein DataBank (accession IDs 6BBU
respectively). We used the SMILES string supplied with the article in which the structure was declared [4
] to generate our representation of the chemical structure. PubChem CID 78323835
represents the strucutre without specified stereochemistry.
Abrocitinib is an immunokinase inhibitor that is is late stage clinical trials for the potential treatment of immune-mediated diseases.