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The Innate lymphoid cells category includes the following Cell Ontology parent terms: |
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![]() Targets Associated to Immuno Cell Types
Full documentation can be found in the GtoImmuPdb immuno cell type data documentation (PDF). ✖ |
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GPCRs | |||
GtoPdb receptor name (family) | Cell Type Association Comments | Cell Ontology Associations | Immunopharmacology Comments |
DP2 receptor (Prostanoid receptors) |
Expression of the DP2 receptor is restricted to eosinophils, basophils, Th2 cells, and innate lymphoid cells. |
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The DP2 receptor (a.k.a. CRTH2, chemoattractant receptor-homologous molecule expressed on T-helper 2 cells) is expressed exclusively by a range of human immune cells including Th2 cells, basophils, eosinophils and innate lymphoid cells [2,5] ... |
C3a receptor (Complement peptide receptors) |
Some lamina propria-derived type 3 innate lymphoid cells express C3aR in the mouse. |
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Complement C3a receptor 1 is the receptor for complement factor C3a, a component of the alternative complement cascade. It can have pro-inflammatory actions, but can also counteract the proinflammatory effects of C5a. The complement system plays a critical role intestinal immune homeostasis. In particular, C3 and the C3aR have been identified as being involved in regulating the intestinal immune response during chronic colitis [7,9] ... |
Enzymes | |||
GtoPdb receptor name (family) | Cell Type Association Comments | Cell Ontology Associations | Immunopharmacology Comments |
dual oxidase 1 (NADPH oxidases) |
DUOX1 expression has been reported in ILCs. |
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DUOX1 participates in innate immune responses to epithelial injury and allergens, and in the development of allergic diseases [8] ... |