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belimumab   Click here for help

GtoPdb Ligand ID: 6887

Synonyms: Benlysta® | hBlySmAb-1.1 | LimphoStat-B | lymphostat-B
Approved drug Immunopharmacology Ligand
belimumab is an approved drug (FDA (2011), EMA (2011))
Compound class: Antibody
Comment: Belimumab is a monoclonal antibody targeting TNFSF13B (BAFF; BLyS) [1,5] , an immunostimulant essential for normal B cell maintenance and humoral immunity [6], and which is reported to be elevated in systemic lupus erythematosus (SLE) and other autoimmune diseases.
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View more information in the IUPHAR Pharmacology Education Project: belimumab

Classification Click here for help
Compound class Antibody
Approved drug? Yes. EU EMA (2011)  |  US FDA (2011)
International Nonproprietary Names Click here for help
INN number INN
8381 belimumab
Synonyms Click here for help
Benlysta® | hBlySmAb-1.1 | LimphoStat-B | lymphostat-B
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 266
Other databases
GtoPdb PubChem SID 178103469
PubChem SID 178103469
Search PubMed clinical trials belimumab
Search PubMed titles belimumab
Search PubMed titles/abstracts belimumab
Wikipedia Belimumab