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The IUPHAR Guide to IMMUNOPHARMACOLOGY ligand list

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GtoImmuPdb ligands only: Low molecular weight, non-polymeric compounds produced via either total synthesis or semi-synthetic processes.
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Ligand name ID Synonyms
A Back to top
852A Immunopharmacology Ligand 9025
A286982 Immunopharmacology Ligand 6592 A 286982, A-286982
A438079 Immunopharmacology Ligand 4118 A 438079, A-438079
AB928 PDB Ligand Immunopharmacology Ligand 11154 AB-928
abediterol Immunopharmacology Ligand 9326 LAS-100977
abrocitinib Approved drug PDB Ligand Immunopharmacology Ligand 9991 Cibinqo®, compound 25 [PMID: 29298069], PF-04965842, PF04965842
ABT-737 PDB Ligand Immunopharmacology Ligand 8320 ABT 737, ABT737, compound 2 [PMID 17256834]
AC430 Immunopharmacology Ligand 9177 AC-430
acalabrutinib Approved drug PDB Ligand Immunopharmacology Ligand 8912 ACP-196, Calquence®, Example 6 [US20140155385 A1]
ACT-1014-6470 Immunopharmacology Ligand 12326 example 172 [WO2019137927A1], Ic-58
ACT-389949 Immunopharmacology Ligand 9511
ACT-660602 Immunopharmacology Ligand 12207 ACT660602, compound 9j [PMID: 35947786]
ACT-777991 Immunopharmacology Ligand 12584 ACT777991, compound 8a [PMID: 36883854]
acumapimod Immunopharmacology Ligand 9203 BCT 197, BCT-197, BCT197, compound A [WO2013139809]
adriforant Immunopharmacology Ligand 8985 PF 3893787, PF-03893787, ZPL-389, ZPL-3893787, ZPL389, ZPL3893787
ADU-S100 Immunopharmacology Ligand 10192 dithio-(Rp,Rp)-[cyclic[A(2',5')pA(3',5')p]], MIW815, ML RR-S2 CDA, S100
agatolimod Immunopharmacology Ligand 9843 CpG 7909, CpG7909, PF 3512676, PF-3512676, ProMune, VaxImmune
AGU654 Immunopharmacology Ligand 13646 AGU-654, compound 44 [PMID: 39622054]
AH10-7 Immunopharmacology Ligand 9899
AH6809 Immunopharmacology Ligand 1896 AH 6809, AH-6809
AJ2-30 Immunopharmacology Ligand 13090 compound 4 [PMID: 38191941]
alcaftadine Approved drug Immunopharmacology Ligand 7587 Lastacaft®, R-89674
alimemazine Approved drug Immunopharmacology Ligand 7237 Nedeltran®, trimeprazine
3 alpha-aminocholestane Immunopharmacology Ligand 9564 3AC, 3 α-aminocholestane
alvelestat Immunopharmacology Ligand 6476 AZD 9668, AZD-9668, AZD9668, KB-105160
AM-461 Immunopharmacology Ligand 10170 AM461, Compound 1 [WO2011085033]
amcinonide Approved drug Immunopharmacology Ligand 7060 CL-34699, Cyclocort®
amelenodor Immunopharmacology Ligand 13384 example 2 [WO2020010132A1], NX-13, NX13
amelubant Immunopharmacology Ligand 8463 BIIL 284, BIIL-284
AMG319 PDB Ligand Immunopharmacology Ligand 8917 AMG 319, AMG-319
AMG487 Immunopharmacology Ligand 13071 AMG 487, AMG-487, compound 47 [PMID: 17448658]
aminopyridine 2 Immunopharmacology Ligand 10051
amiselimod Immunopharmacology Ligand 9319 Example 1 [US20090137530], MT-1303, MT1303
amiselimod phosphate Immunopharmacology Ligand 9491 amiselimod-P, MT-1303-P
amlexanox Approved drug PDB Ligand Immunopharmacology Ligand 7113 AA-673, Amlexanox®, Aphthasol®, CHX-3673
ancriviroc Immunopharmacology Ligand 804 SCH 351125, SCH-351125, SCH-C
andrographolide Immunopharmacology Ligand 9675
apafant Immunopharmacology Ligand 1860 WEB 2086 BS, WEB-2086
apilimod Immunopharmacology Ligand 9859 LAM-002A (apilimod dimesylate), LAM002A, STA 5326, STA-5326, STA5326
apratastat Immunopharmacology Ligand 6482 compound 5h [PMID: 16426848], TMI-05, TMI005
apremilast Approved drug PDB Ligand Immunopharmacology Ligand 7372 CC-10004, Otezla®
AR-9281 Immunopharmacology Ligand 13112 AR9281, compound 14a [PMID: 21211973]
arformoterol Approved drug PDB Ligand Immunopharmacology Ligand 7479 (-)-Formoterol, (R,R)-Formoterol, Brovana®, YM-08316
ARN19702 PDB Ligand Immunopharmacology Ligand 10120 ARN-19702, compound 8 [PMID: 27404798]
ARN726 Immunopharmacology Ligand 9178 ARN-726, compound 6 [PMID: 25874594]
(R)-ARN2508 Immunopharmacology Ligand 9000 compound (-)-10r [PMID: 26774927], example 19 [WO2014023643]
(S)-ARN2508 PDB Ligand Immunopharmacology Ligand 8999 compound (+)-10r [PMID: 26774927], example 20 [WO2014023643]
arpromidine Immunopharmacology Ligand 1221 ARP
ARRY-371797 Immunopharmacology Ligand 11095 ARRY-797, ARRY371797, ARRY797, compound 7 [PMID: 19950901]
ARRY-382 Immunopharmacology Ligand 9108 ARRY 382, ARRY382, c-Fms-IN-12, PF-07265804, PF07265804
ARRY-502 Immunopharmacology Ligand 10179 ARRY502, example 237, enantiomer 1 [WO2009158426A1]
AS101 Immunopharmacology Ligand 437 ammonium tri-chloro(dioxoethylene-O,O'-)tellurate, AS 101, AS-101
AS-252424 Immunopharmacology Ligand 10578 AS252424, compound 26 [PMID: 16789742]
asapiprant Immunopharmacology Ligand 11951 BGE-175, BGE175, example II-74 [US8153793B2], S-555739
asimadoline Immunopharmacology Ligand 9279 EMD 61 753, EMD 61753, EMD-61753
asivatrep Immunopharmacology Ligand 9621 Example 230 [US7858621], PAC-14028
ASP4058 Immunopharmacology Ligand 9569 ASP-4058
aspirin Approved drug PDB Ligand Immunopharmacology Ligand 4139 Acetophen®, acetylsalicylic acid, Aspirin®
AT38 Immunopharmacology Ligand 9020 [3-(aminocarbonyl)furoxan-4-yl]methyl salicylate
ATI-50001 Immunopharmacology Ligand 12317 ATI-501, ATI50001, ATI501, example 103 [WO2007070872A1]
atracurium Approved drug Immunopharmacology Ligand 9537 atracurium besilate, atracurium dibesylate, BW 33A, Tracrium®
auranofin Approved drug Immunopharmacology Ligand 6306 MMV688978, Ridaura®, SK&F-39162, SK-39162
avacopan Approved drug PDB Ligand Immunopharmacology Ligand 9450 CCX-168, CCX168, Tavneos®
avadomide Immunopharmacology Ligand 10522 CC-122, CC122, Compound A [WO2014039960A1]
avapritinib Approved drug PDB Ligand Immunopharmacology Ligand 10368 Ayvakit®, Ayvakyt®, BLU-285, BLU285
AVE 0991 Immunopharmacology Ligand 5579 AVE-0991, AVE0991
AX-024 Immunopharmacology Ligand 11253 AX-24, AX024
AZ13102909 Immunopharmacology Ligand 9577 AZ909
AZ2 PDB Ligand Immunopharmacology Ligand 10233
AZ3246 PDB Ligand Immunopharmacology Ligand 13722 AZ-3246, compound 24 [PMID: 39928839]
AZ3451 PDB Ligand Immunopharmacology Ligand 9560
AZ7188 Immunopharmacology Ligand 9586
AZ8838 PDB Ligand Immunopharmacology Ligand 9585
azacitidine Approved drug PDB Ligand Immunopharmacology Ligand 6796 5-AZAC, 5-azacytidine, ladakamycin, Onureg®, Onureg® (CC-486; oral azacitidine), U-18496, Vidaza®
azatadine Approved drug Immunopharmacology Ligand 7119 Optimine®, SCH-10649
azathioprine Approved drug Immunopharmacology Ligand 7120 Azasan®, BW-57-322, Imuran®, Jayempi®
AZD0284 PDB Ligand Immunopharmacology Ligand 11711 AZD-0284, compound 20 [PMID: 34464130]
AZD1236 Immunopharmacology Ligand 7844 AZD 1236, AZD-1236
AZD1678 Immunopharmacology Ligand 9679 AZD-1678, compound 49 [PMID: 28947948]
AZD1981 Immunopharmacology Ligand 7680 AZD 1981, AZD-1981
AZD2098 Immunopharmacology Ligand 9678 AZD-2098, compound 47 [PMID: 28947948]
AZD2423 Immunopharmacology Ligand 7825 AZD 2423, AZD-2423
AZD3458 Immunopharmacology Ligand 9997 AZD-3458, compound 15 [PMID: 29852070]
AZD3965 Immunopharmacology Ligand 10605 AZD-3965
AZD5069 Immunopharmacology Ligand 8948 AZD-5069
AZD5423 PDB Ligand Immunopharmacology Ligand 13017 AZD-5423, compound 1b [PMID: 28937774]
AZD5672 Immunopharmacology Ligand 7686 AZD 5672, AZD-5672
AZD5718 Immunopharmacology Ligand 10352 compound 12 [PMID: 30869888]
AZD6605 Immunopharmacology Ligand 7823 AZ 11920155, AZ-11920155, AZ11920155, AZD 6605, AZD-6605
AZD6703 PDB Ligand Immunopharmacology Ligand 7687 AZ 12012199, AZ-12012199, AZ12012199, AZD 6703, AZD-6703
AZD7624 Immunopharmacology Ligand 11714 AZD-7624, Example 259 [WO2009001132]
AZD8154 PDB Ligand Immunopharmacology Ligand 11204 AZD-8154, Example 1 [WO2018055040A1]
AZD8848 Immunopharmacology Ligand 9256 DSP-3025
AZD9056 Immunopharmacology Ligand 7826 AZD 9056, AZD-9056
AZD9567 PDB Ligand Immunopharmacology Ligand 9812 AZD 9567, AZD-9567, compound 15 [PMID: 29424542], example 1 [WO2016046260A1]
AZD9898 PDB Ligand Immunopharmacology Ligand 10479 AZD-9898, example 62 [WO2016177845A1]
azelaic acid Approved drug PDB Ligand Immunopharmacology Ligand 7484 Azelex®, Finacea®, ZK-62498
azithromycin Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6510
AZ11657312 (salt free) Immunopharmacology Ligand 7722
 
B Back to top
bafetinib PDB Ligand Immunopharmacology Ligand 7906 INNO-406, Lyn-IN-1, NS-187
balamapimod Immunopharmacology Ligand 9925 MKI-833, MKI833
balinatunfib Immunopharmacology Ligand 13583 SAR-441566, SAR441566
bardoxolone Immunopharmacology Ligand 2717 CDDO, RTA-401
baricitinib Approved drug PDB Ligand Immunopharmacology Ligand 7792 INCB-028050, INCB028050, LY-3009104, LY3009104, Olumiant®
BAY 11-7082 Immunopharmacology Ligand 5934 (E)-3-tosylacrylonitrile, BAY-117082, BAY117082
BAY1830839 PDB Ligand Immunopharmacology Ligand 13101 BAY-1830839, example 11 [WO2016083433A1]
BAY-985 Immunopharmacology Ligand 10597 BAY985, compound 34 [PMID: 31859507]
BAYu9773 Immunopharmacology Ligand 3381 BAY u9773, BAY-u 9773
BC-1215 Immunopharmacology Ligand 12671 BC 1215, BC1215
beclometasone Approved drug PDB Ligand Immunopharmacology Ligand 7059 beclomethasone, SCH-18020W
beclometasone dipropionate Approved drug Immunopharmacology Ligand 5894 beclomethasone dipropionate, Beconase®, Qnasl®, Vancenase®
belnacasan Immunopharmacology Ligand 9035 HMR3480, VX-765
belumosudil Approved drug PDB Ligand Immunopharmacology Ligand 9558 KD-025, KD025, Rezurock®, SLx 2119, SLx2119
bentamapimod Immunopharmacology Ligand 9926 AS-602801, AS602801, PGL-5001, PGL5001
benzodrocortisone Immunopharmacology Ligand 9731 compound 1 [WO2013071010], hydrocortisone 17-benzoate
3beta-Hydroxy-20(29)-lupene Immunopharmacology Ligand 9028 Fagarasterol, Lupeol
BI-1935 Immunopharmacology Ligand 9717 BI 1935, example 3 [WO2007067836]
BI-1950 Immunopharmacology Ligand 9719
BI-2545 PDB Ligand Immunopharmacology Ligand 9791 BI2545, compound 19 [PMID: 29259743]
BI605906 Immunopharmacology Ligand 9357 3-Amino-4-(1,1-difluoro- propyl)-6-(4-methanesulfonyl- piperidin-1-yl)-thieno[2,3- b]pyridine-2-carboxylic acid amide, compound 115 [US20070293533]
BI 653048 Immunopharmacology Ligand 9715 (R)-39, BI 653048 BS H3PO4, BI-653048, BI653048
BI 665915 Immunopharmacology Ligand 9716 BI-665915, compound 69 [PMID: 25671290]
BI-6901 Immunopharmacology Ligand 9714 BI 6901, BI 6901, BI6901, eut-22
BIIB068 PDB Ligand Immunopharmacology Ligand 11178 BIIB-068, compound 1 [PMID: 32696648]
bimosiamose Immunopharmacology Ligand 9049 compound 15e [PMID: 9544210], TBC 1269, TBC-1269, TBC1269
bindarit Immunopharmacology Ligand 11124 AF-2838, AF2838
BIO-7488 Immunopharmacology Ligand 13341 BIO7488
BIO-8169 Immunopharmacology Ligand 13355 BIO8169, compound 2 [PMID: 38695469]
BIRT 377 Immunopharmacology Ligand 9720 BIRT-377
BML-281 Immunopharmacology Ligand 9664 compound 3 [PMID: 18642892]
BMS-1001 Immunopharmacology Ligand 10191 BMS1001, Example 1001 [WO2015160641A2]
BMS-1166 Immunopharmacology Ligand 9608 compound 2c [PMID: 28613862], Example 1166 [WO2015160641A2]
BMS-202 PDB Ligand Immunopharmacology Ligand 9607 compound 1c [PMID: 28613862], PD1-PDL1 inhibitor 2
BMS-345541 Immunopharmacology Ligand 5669 BMS 345541, BMS345541
BMS-509744 Immunopharmacology Ligand 9994 BMS 509744, BMS509744, compound 3 [PMID:16682193]
BMS-561392 Immunopharmacology Ligand 6509 BMS 561392, BMS561392, DPC-333
BMS-582949 PDB Ligand Immunopharmacology Ligand 7838 BMS 582949, BMS582949, PS 540446, PS-540446, PS540446
BMS-681 PDB Ligand Immunopharmacology Ligand 9430 compound 13d [PMID: 25893046]
BMS-817399 PDB Ligand Immunopharmacology Ligand 9497 compound 29 [PMID: 25101488]
BMS-986142 PDB Ligand Immunopharmacology Ligand 9857 BMS986142, compound 14f [PMID: 27583770]
BMS-986166 Immunopharmacology Ligand 11493 BMS986166, compound 14a [PMID: 30785748]
BMS-986235 Immunopharmacology Ligand 11024 BMS986235, compound 13c [PMID: 32407089], LAR-1219, LAR1219
BMS-986260 PDB Ligand Immunopharmacology Ligand 10662 BMS986260, compound 10 [Velaparthi et al., 2020], Example 32' [WO2016140884A1]
BMS-986104 derivative 12 Immunopharmacology Ligand 11494 compound 12 [PMID: 33492963]
BMS-986104 derivative 24 Immunopharmacology Ligand 11495 compound 24 [PMID: 33492963]
bortezomib Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6391 peptide boronate, PS-341, Velcade®
bosutinib Approved drug PDB Ligand Immunopharmacology Ligand 5710 Bosulif®, SK 606, SK-606, SKI 606
branebrutinib Immunopharmacology Ligand 9869 BMS-986195, BMS986195, Example 223 [US20160115126A1]
brensocatib Immunopharmacology Ligand 9412 AZD7986, compound 30, INS 1007, INS1007
brepocitinib PDB Ligand Immunopharmacology Ligand 10459 compound 23 [PMID: 30113844], PF-06700841, PF06700841
brimonidine (UK14304) Approved drug PDB Ligand Immunopharmacology Ligand 520 Alphagan®, Lumify®, Mirvaso®, UK14,304, UK14304
BRL-15572 Immunopharmacology Ligand 10 BRL 15572, BRL-15,572, BRL15572
bromfenac Approved drug PDB Ligand Immunopharmacology Ligand 7131 AHR-10282B, Bromday®, Prolensa®, Xibrom®
BTP2 Immunopharmacology Ligand 2438 YM-58483
budesonide Approved drug Immunopharmacology Ligand 7434 Entocort®, Eohilia® (budesonide oral suspension), Jorveza®, Pulmicort®, S-1320, Uceris®
BX 471 Immunopharmacology Ligand 767 BX-471, BX-741
BX-795 PDB Ligand Immunopharmacology Ligand 8006 BX 795, BX795
 
C Back to top
C108297 Immunopharmacology Ligand 9180 Compound 52 [PMID:18226897]
C1-27 PDB Ligand Immunopharmacology Ligand 10719 GSTO1-IN-1
C-176 Immunopharmacology Ligand 13136 C-176 STING inhibitor
C391 Immunopharmacology Ligand 9570 compound 5 [PMID: 27994760]
C646 Immunopharmacology Ligand 7004
cambritaxestat PDB Ligand Immunopharmacology Ligand 13506 compound 9v [PMID: 27780639], CRT-0273750, CRT0273750, IOA-289
canertinib Immunopharmacology Ligand 5675 CI 1033, CI-1033, PD 183805 dihydrochloride
carotegrast Immunopharmacology Ligand 10511 HCA2969
carotegrast methyl Approved drug Immunopharmacology Ligand 10510 AJM-300, AJM300, Carogra®
carprofen Approved drug Immunopharmacology Ligand 7141 Ro-205720000
CBS-3595 Immunopharmacology Ligand 9610
CC-885 Immunopharmacology Ligand 9224
CCR2-RA-[R] PDB Ligand Immunopharmacology Ligand 9431 analog 49 (Dasse et al., 2007)
CCX354 Immunopharmacology Ligand 10164 CCX 354, CCX-354, CCX-354-C
CDP840 Immunopharmacology Ligand 9330 CDP 840, CDP-840
CEE321 Immunopharmacology Ligand 12350 CEE-321, compound 1e [PMID: 36657024]
celecoxib Approved drug PDB Ligand Immunopharmacology Ligand 2892 Celecox®, Elyxyb® (DFN-15; oral solution), Onsenal®, SC-58635, SC58635
cenerimod PDB Ligand Immunopharmacology Ligand 9824 ACT-334441
cenicriviroc Immunopharmacology Ligand 801 TAK 652, TAK-652, TAK652, TBR-652
cerdulatinib PDB Ligand Immunopharmacology Ligand 8957 PRT 062070, PRT-062070, PRT-2070, PRT062070
cetirizine Approved drug Immunopharmacology Ligand 1222 Reactine®, Zyrtec®
CG200745 Immunopharmacology Ligand 10055 CG-2, CG-200745, HDCG-0745
CGI1746 PDB Ligand Immunopharmacology Ligand 8066 CGI 1746, CGI-1746
CGI560 Immunopharmacology Ligand 9264 CGI-560
CH-4051 Immunopharmacology Ligand 9844 Formula (10) [WO2012078708A1]
chloroquine Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 5535 Aralen®, chloraquine, Malaquin®
CHMFL-BTK-11 Immunopharmacology Ligand 9516
cicaprost Immunopharmacology Ligand 1917 ZK 96480, ZK-96480
ciclesonide Approved drug Immunopharmacology Ligand 7469 Alvesco®, Omnaris®, RPR-251526
ciforadenant Immunopharmacology Ligand 10190 CPI-444, CPI444, V-81444, V81444
cilomilast PDB Ligand Immunopharmacology Ligand 7407 SB-207499
cintirorgon Immunopharmacology Ligand 10045 compound 32J [WO2016201225A1], LYC-55716, LYC55716
cipemastat Immunopharmacology Ligand 6466 Ro 28-2653
civorebrutinib Immunopharmacology Ligand 12868
clemastine Approved drug Immunopharmacology Ligand 6063 HS-592, meclastin, Tavegil®, Tavist®
clemizole PDB Ligand Immunopharmacology Ligand 10285
clobenpropit PDB Ligand Immunopharmacology Ligand 1223 VUF 9153, VUF-9153
clobetasol propionate Approved drug PDB Ligand Immunopharmacology Ligand 7062 CCI-4725, Clobex®, Dermovate®, GR 2/925, Temovate®
clobetasone Approved drug Immunopharmacology Ligand 9088 Eumovate®
clodronic acid Approved drug Immunopharmacology Ligand 9605 Bonefos®, Clasteon ®, clodronate, Loron®
clofazimine Approved drug Immunopharmacology Ligand 9184 Lamprene®
clopidogrel (active metabolite) Immunopharmacology Ligand 1772
CM4620 Immunopharmacology Ligand 10087 CM-4620, compound I [WO2016138472A1]
CNX-774 Immunopharmacology Ligand 9266
colchicine Approved drug PDB Ligand Immunopharmacology Ligand 2367 Colcrys®, methoxylated analogue of XD1, XD25
compound 48/80 PDB Ligand Immunopharmacology Ligand 5531
compound 3a [Pipionne et al, 2018] Immunopharmacology Ligand 9965
compound 10a [PMID: 31283223] Immunopharmacology Ligand 10435
compound 12a [PMID: 29031075] Immunopharmacology Ligand 9684
compound 19a [PMID: 26506089] Immunopharmacology Ligand 9842
compound 8a [PMID: 23713581] Immunopharmacology Ligand 8856
compound 21b [PMID: 31136173] Immunopharmacology Ligand 10403
compound 5b [PMID: 29457898] Immunopharmacology Ligand 9835
compound 5b [PMID: 31287314] Immunopharmacology Ligand 10434
compound 18c [PMID: 25901531] Immunopharmacology Ligand 9227
compound 7c [PMID: 22041175] Immunopharmacology Ligand 9931
compound 8c [PMID: 28760529] Immunopharmacology Ligand 9671
Compound 9 [doi:10.26434/chemrxiv.7072592.v1] Immunopharmacology Ligand 10083
compound 17d [PMID: 23099093] Immunopharmacology Ligand 8196
compound 5d [PMID: 31335136] Immunopharmacology Ligand 10441 Example 59 [WO2018121550]
compound 7d [PMID: 29672049] Immunopharmacology Ligand 9937
compound 18e [PMID: 31670517] PDB Ligand Immunopharmacology Ligand 10549
compound 4e [PMID: 35546685] Immunopharmacology Ligand 12122 CHF-6297, CHF6297, CHI 91040, CHI91040, p38α MAPK-IN-5
compound 5e [PMID: 28580438] Immunopharmacology Ligand 9712
compound 14f [PMID: 35063894] Immunopharmacology Ligand 11936
compound 20f [PMID: 28520415] Immunopharmacology Ligand 9961
compound 7f [PMID: 29191554] PDB Ligand Immunopharmacology Ligand 9794 example 32 [WO2011078413]
compound 7f [PMID: 29283260] Immunopharmacology Ligand 9780
compound 2g [PMID: 27390066] Immunopharmacology Ligand 9682
compound 4g [PMID: 2680437] Immunopharmacology Ligand 9198
compound G1 [PMID: 36689364] Immunopharmacology Ligand 12354
compound 8ic [PMID: 19081254] Immunopharmacology Ligand 9478 CCR4 Antagonist
compound III [PMID: 24045148] Immunopharmacology Ligand 9709
compound II [PMID: 21329883] Immunopharmacology Ligand 9579
compound 16i [PMID: 31525963] Immunopharmacology Ligand 10502
compound 5i [PMID: 36542759] Immunopharmacology Ligand 12336
compound 9 [Kumar et al., 2019] Immunopharmacology Ligand 10448
compound 17l [PMID: 26288691] Immunopharmacology Ligand 10035
compound 29 [Moslin et al., 2017] Immunopharmacology Ligand 9992
compound 12p [Larson et al., 2017] Immunopharmacology Ligand 9690
compound 10 [PMID: 31411465] Immunopharmacology Ligand 10488 example 8 (cis racemate) [WO2017060855A1]
compound 11 [PMID: 29442501] Immunopharmacology Ligand 9819
compound 12 [PMID: 27448772] PDB Ligand Immunopharmacology Ligand 9453
compound 15 [PMID: 25411721] Immunopharmacology Ligand 9078 example 252 [WO2007110237]
compound 15 [PMID: 32045236] Immunopharmacology Ligand 10706
compound 16 [PMID: 26794040] Immunopharmacology Ligand 9223
compound 16 [PMID: 31525966] Immunopharmacology Ligand 10501
compound 17 [PMID: 29741897] Immunopharmacology Ligand 10005
compound 182 [PMID: 37500611] PDB Ligand Immunopharmacology Ligand 13005 compound XI [PMID: 37500611]
compound 1 [PMID: 24930776] Immunopharmacology Ligand 9092 DB36
compound 1 [PMID: 28611375] Immunopharmacology Ligand 9673
compound 1 [PMID: 31477924] Immunopharmacology Ligand 10481
compound 21 [PMID: 22802221] Immunopharmacology Ligand 6918 3-[4-(1H-imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)thiophene-2-[(N-butyloxylcarbamate)-sulphonamide] sodium salt, C21
compound 21 [PMID: 24900635] Immunopharmacology Ligand 8187
compound 24 [PMID: 26987013 ] Immunopharmacology Ligand 9252
compound 25 [PMID: 28038940] Immunopharmacology Ligand 9700
compound 25 [PMID: 31260299] Immunopharmacology Ligand 10428
compound 25 [PMID: 32105470] Immunopharmacology Ligand 10718
compound 25 [PMID: 32687365] Immunopharmacology Ligand 11130
compound 26 [PMID: 31710475] Immunopharmacology Ligand 10602
compound 27 [PMID: 24900635] Immunopharmacology Ligand 10133
compound 28 [PMID: 28671460] Immunopharmacology Ligand 9670
compound 29 [PMID: 31934767] Immunopharmacology Ligand 10596
compound 2 [PMID: 28621538] PDB Ligand Immunopharmacology Ligand 11282 example 727 [WO2012093101A1]
compound 31 [PMID: 31259550] Immunopharmacology Ligand 10417
compound 32 [PMID: 31638797] Immunopharmacology Ligand 10528 example 69 [WO2016179460A1]
compound 32 [PMID: 38047891] Immunopharmacology Ligand 13050
compound 36 [PMID: 21958547] Immunopharmacology Ligand 9391
compound 37 [PMID: 29193967] Immunopharmacology Ligand 9797
compound 39 [PMID: 31742400] Immunopharmacology Ligand 10585
compound 3 [PMID: 28603634] Immunopharmacology Ligand 9628
compound 3 [PMID: 29633584] Immunopharmacology Ligand 9960
compound 41 [PMID: 25000588] Immunopharmacology Ligand 9349
compound 41 [PMID: 31855425] PDB Ligand Immunopharmacology Ligand 10598
compound 43 [PMID: 26751273] Immunopharmacology Ligand 9492
compound 47 [PMID: 28737909] Immunopharmacology Ligand 9646
compound 49 [PMID: 36529947] Immunopharmacology Ligand 12355
compound 52 [PMID: 28541707] Immunopharmacology Ligand 10001
compound 76 [PMID: 28657314] Immunopharmacology Ligand 9609
compound 7 [PMID: 31381331] Immunopharmacology Ligand 10450
compound 8 [PMID: 25898023] Immunopharmacology Ligand 10498
compound 9 [PMID: 26006010] Immunopharmacology Ligand 9761
compound (S)-29 [PMID: 37606563] Immunopharmacology Ligand 12904
compound 2q [PMID: 30986068] PDB Ligand Immunopharmacology Ligand 10365 example 2-8 [US20150353552]
compound 14 [Schnute et al., 2023] Immunopharmacology Ligand 12351
compound T.14 Immunopharmacology Ligand 10385
compound 8u [PMID: 31999451] Immunopharmacology Ligand 10682
compound 3v [PMID: 27390066] Immunopharmacology Ligand 9683
compound 1 [WO2012007375] Immunopharmacology Ligand 8084
compound 7 [WO2012007375] Immunopharmacology Ligand 8085
compound 71 [WO2018191577A1] Immunopharmacology Ligand 11203
compound XVI [PMID: 38863440] Immunopharmacology Ligand 13423
compound 25 [Zhang et al., 2020] PDB Ligand Immunopharmacology Ligand 10643 example 6B [WO2014028600A2]
compound 15z [PMID: 38029358] Immunopharmacology Ligand 13044 NLRP3 inhibitor 15z
CORM-2 Immunopharmacology Ligand 9535
CP105696 Immunopharmacology Ligand 3368 CP 105696, CP-105,696, CP-105696
CP-195543 Immunopharmacology Ligand 6155 CP 195543, CP-195,543, CP195543
CP-412,245 Immunopharmacology Ligand 11809
CP-424,174 Immunopharmacology Ligand 11810 CP-424174
CpdA (parent molecule) Immunopharmacology Ligand 11317
CPUY192018 Immunopharmacology Ligand 9710 compound 18e [PMID: 26258437], compound 2 [PMID: 24512214]
CR6086 Immunopharmacology Ligand 9845
CRAC channel inhibitor 5b [PMID: 26256403] Immunopharmacology Ligand 10042
CRAC channel inhibitor 1 [PMID: 26256403] Immunopharmacology Ligand 10041
crenolanib PDB Ligand Immunopharmacology Ligand 7882 ARO-002, CP 868596, CP-868,596, CP-868596
crisaborole Approved drug Immunopharmacology Ligand 9151 AN 2728, AN2728, compound 5b [PMID: 19303290], Eucrisa®, Staquis®
crizotinib Approved drug PDB Ligand Immunopharmacology Ligand 4903 (R)-crizotinib, PF 2341066, PF-02341066, PF-2341066, PF2341066, Xalkori®
cromoglicic acid Approved drug Immunopharmacology Ligand 7608 cromoglycate, cromolyn, cromolyn sodium, FPL-670, Intal®, Opticrom®, sodium cromoglicate
CRX-555 Immunopharmacology Ligand 10091 CRX555, N-[(3R)-3-(Octanoyloxy)myristoyl]-O-[2-[[(3R)-3-(octanoyloxy)myristoyl]amino]-3-O-[(3R)-3-(octanoyloxy)myristoyl]-4-O-phosphono-2-deoxy-beta-D-glucopyranosyl]-L-serine
CU-CPT8m PDB Ligand Immunopharmacology Ligand 9795 7-(m-Tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide, compound 5 [PMID: 29155428]
CVN293 Immunopharmacology Ligand 13373 CVN-293
CX549 Immunopharmacology Ligand 9701 compound 63 [WO2016048861], CX-549
CXCR4 antagonist 22 Immunopharmacology Ligand 10146
CY-09 Immunopharmacology Ligand 10057
cyclic di-GMP PDB Ligand Immunopharmacology Ligand 13137 Bis-(3'-5')-cyclic dimeric guanosine monophosphate, c-di-GMP, cGpGp, dyclic diguanylate monophosphate
CZ415 Immunopharmacology Ligand 9837 compound 3 [PMID: 27563401], CZ-415
 
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D4476 Immunopharmacology Ligand 5940 casein kinase I inhibitor, CK1 inhibitor, D 4476
dagrocorat Immunopharmacology Ligand 9650 PF-00251802
danirixin Immunopharmacology Ligand 8500 GSK-1325756B, GSK1325756, GSK1325756B
dapansutrile Immunopharmacology Ligand 10056 OLT-1177, OLT1177
darapladib PDB Ligand Immunopharmacology Ligand 6696 SB 480848, SB-480848
dasatinib Approved drug PDB Ligand Immunopharmacology Ligand 5678 BMS 345825, BMS 354825, BMS 35482513, Sprycel®
DDR1/2 inhibitor 5n PDB Ligand Immunopharmacology Ligand 10105
decernotinib PDB Ligand Immunopharmacology Ligand 8309 adelatinib, VRT-831509, VX-509
deflazacort Approved drug Immunopharmacology Ligand 9477 Emflaza®, MDL 458
defoslimod Immunopharmacology Ligand 9024 OM 174, OM-174
delgocitinib Approved drug PDB Ligand Immunopharmacology Ligand 9619 Anzupgo®, Corectim®, ent-60, JTE-052, JTE052
desloratadine Approved drug PDB Ligand Immunopharmacology Ligand 7157 Clarinex®, SCH-34117
desonide Approved drug Immunopharmacology Ligand 7066 D-2083, Desowen®
deucravacitinib Approved drug Immunopharmacology Ligand 10432 BMS-986165, BMS986165, compound 11 [PMID: 31318208}, Sotyktu®, Tyk2-IN-4
deuruxolitinib Approved drug Immunopharmacology Ligand 11410 CTP-543, CTP543, D8-ruxolitinib, Leqselvi®
dexamethasone Approved drug PDB Ligand Immunopharmacology Ligand 2768 Decadron®, desametasone, fluormethylprednisolone
dezapelisib Immunopharmacology Ligand 9728 compound 67 [PMID: 22924688], example 15 [WO2011008487], INCB 40093, INCB40093
(R)-DFV890 PDB Ligand Immunopharmacology Ligand 13782 compound (R)-1 [PMID: 40036600], DFV-890, IFM-2427, IFM2427
diamorphine Immunopharmacology Ligand 9082 acetomorphine, diacetylmorphine, heroin
diclofenac Approved drug PDB Ligand Immunopharmacology Ligand 2714 Cataflam®, CGP-45840B, GP-45840, Voltaren®, Voltarol®
difamilast Approved drug Immunopharmacology Ligand 9776 example 352 [WO2007058338], MM36, Moizerto®, OPA-15406
diflapolin Immunopharmacology Ligand 10080
diflorasone diacetate Approved drug Immunopharmacology Ligand 7068 Psorcon®, U-34865
diflunisal Approved drug PDB Ligand Immunopharmacology Ligand 7162 Dolobid®
difluprednate Approved drug Immunopharmacology Ligand 7474 DFBA, Durezol®, W-6309
dilmapimod Immunopharmacology Ligand 7815 SB-681323
dimethyl fumarate Approved drug PDB Ligand Immunopharmacology Ligand 7045 BG-12, BG00012, fumaric acid, Tecfidera®
dimethyl itaconate Immunopharmacology Ligand 9939 dimethylitaconate, itaconic acid dimethyl ester
dimetindene Approved drug Immunopharmacology Ligand 10101 (+/-)-dimethindene, dimethindene, dimethpyrindene, Fenistil®, Vibrocil®
(S)-dimetindene Immunopharmacology Ligand 10104 (+)-dimethindene, (+)-dimetindene, (S)-dimethindene
diminazene PDB Ligand Immunopharmacology Ligand 10307 Azidin®, Berenil®, Pirocide®
dinaciclib Immunopharmacology Ligand 7379 SCH727965
diphenylpyraline Approved drug Immunopharmacology Ligand 7165 Hispril®
diprovocim-1 PDB Ligand Immunopharmacology Ligand 10341 compound 3 [PMID: 30272974]
diroleuton PDB Ligand Immunopharmacology Ligand 9775 8,11,14-Eicosatrienoic acid, DGLA, dihomo-gamma-linolenic acid, DS107, Homo-gamma-linolenic acid
diroximel fumarate Approved drug Immunopharmacology Ligand 10525 ALKS-8700, ALKS8700, BIIB098, Vumerity®
DMAT PDB Ligand Immunopharmacology Ligand 9323 2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole, CK2 Inhibitor II
DO264 Immunopharmacology Ligand 10250 compound 46, DO-264
doramapimod PDB Ligand Immunopharmacology Ligand 5668 BIRB 796BS, BIRB-796, BIRB796
doxycycline Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6464 BMY-28689, Monodox®, Vibramycin®
dual sEH/FAAH inhibitor 11 Immunopharmacology Ligand 10124 compound B-11 [WO2017160861], example 28 [WO2017160861]
dubermatinib Immunopharmacology Ligand 8863 compound 13, TP 0903, TP-0903, TP0903
duvelisib Approved drug Immunopharmacology Ligand 7795 compound 4904 [Patent US8193182], Copiktra®, INK-1197, IPI-145
 
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6E11 Immunopharmacology Ligand 9749
E-52862 PDB Ligand Immunopharmacology Ligand 10431 compound 28 [PMID: 22784008], E52862, MR309, sigma 1 receptor antagonist (S1RA)
E6201 PDB Ligand Immunopharmacology Ligand 7836 E 6201, E-6201
edicotinib Immunopharmacology Ligand 8942 JNJ-40346527, JNJ40346527, US8497376, 15
EG01377 PDB Ligand Immunopharmacology Ligand 9904 (3-((5-(4-(aminomethyl)phenyl)-2,3-dihydrobenzofuran)-7-sulfonamido)thiophene- 2-carbonyl)-L-arginine, compound 1 [PMID: 29648813]
eganelisib PDB Ligand Immunopharmacology Ligand 9563 compound 26 [PMID: 27660692], IPI-549, IPI549
elenestinib Immunopharmacology Ligand 12357 BLU-263, BLU263, exampl4 4 [WO2020210293A1]
elsubrutinib Immunopharmacology Ligand 10464 example #30 (S) [WO2014210255A1]
elubirixin Immunopharmacology Ligand 8499 SB 656933, SB-656933, SB656933
emavusertib PDB Ligand Immunopharmacology Ligand 10152 AU-4948, AU4948, CA4948, compound 24 [PMID: 33335659]
emlenoflast Immunopharmacology Ligand 12172 Inzomelid, MCC-7840, MCC7840
enpatoran PDB Ligand Immunopharmacology Ligand 11307 compound 73 [WO2017106607A1], M-5049, M5049
ensifentrine Approved drug Immunopharmacology Ligand 11865 Ohtuvayre®, RPL554, VMX 554, VMX-554, VMX554
epacadostat PDB Ligand Immunopharmacology Ligand 8221 IDO inhibitor 1, INCB 24360, INCB-24360, INCB024360
epinastine Approved drug Immunopharmacology Ligand 7176 Elestat®, epinastine hydrochloride
ER-27319 Immunopharmacology Ligand 9611
esflurbiprofen Approved drug PDB Ligand Immunopharmacology Ligand 9420 (S)-flurbiprofen, BTS-24332, SFPP, TT-063
etodolac Approved drug Immunopharmacology Ligand 7185 AY-24236, Lodine®
etoricoxib Approved drug PDB Ligand Immunopharmacology Ligand 2896 Arcoxia®, MK 0663, MK-0663, MK0663
etrasimod Approved drug Immunopharmacology Ligand 9331 APD-334, APD334, APD334-003, compound 4 [PMID: 25516790], Velsipity®
everolimus Approved drug Immunopharmacology Ligand 5889 Afinitor®, Certican®, RAD-001, RAD001, rapamycin, 42-O-(2-hydroxyethyl)-, Zortress®
evobrutinib PDB Ligand Immunopharmacology Ligand 9752 A250 [WO2012170976], M-2951, M2951, MSC 2364447, MSC-2364447C, MSC2364447C
example 131 [WO2009133348] Immunopharmacology Ligand 8489
example 25 [WO2018228934] Immunopharmacology Ligand 10201
example 36 [WO2016177845] Immunopharmacology Ligand 9555
Example 4 [WO2017202275A1] Immunopharmacology Ligand 10449
 
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F16357 Immunopharmacology Ligand 9255 Compound 39 [PMID: 19791800], Example 1 in WO2007147824
F215 Immunopharmacology Ligand 10121
fenebrutinib PDB Ligand Immunopharmacology Ligand 9299 Example 130 [US20140194408], GDC-0853, GDC0853, RG-7845, RG7845
fenoprofen Approved drug Immunopharmacology Ligand 4820 fenoprofen calcium, Nalfon®
fevipiprant PDB Ligand Immunopharmacology Ligand 8995 NVP-QAW039, QAW039
fexofenadine Approved drug Immunopharmacology Ligand 4819 Allegra®, fexofenadine HCl
filgotinib Approved drug PDB Ligand Immunopharmacology Ligand 7913 GLPG-0634, GLPG0634, Jyseleca®
fimepinostat Immunopharmacology Ligand 8952 CUDC 907, CUDC-907, PI3K/HDAC Inhibitor centn
fingolimod Approved drug Immunopharmacology Ligand 2407 FTY-720, FTY720, Gilenya®
FIPI Immunopharmacology Ligand 8781 compound 14 [PMID: 19136975]
firategrast Immunopharmacology Ligand 11486 SB-683699, SB683699
fludroxycortide Approved drug Immunopharmacology Ligand 7606 Cordran®, flurandrenolide, flurandrenolone, Haelan®
flufenamic acid Approved drug PDB Ligand Immunopharmacology Ligand 2447
flumethasone pivalate Approved drug Immunopharmacology Ligand 7075 Locorten®
flunisolide Approved drug Immunopharmacology Ligand 7076 AeroBid®, RS-3999
fluocinolone acetonide Approved drug Immunopharmacology Ligand 7077 Capex®, Iluvien®, Synalar®
fluocinonide Approved drug Immunopharmacology Ligand 7078 Fluonex®, Lidex®
fluorescent MIF ligand B Ligand is labelled Immunopharmacology Ligand 9987
fluorometholone Approved drug Immunopharmacology Ligand 7079 Flarex®, FML®
flurbiprofen Approved drug Immunopharmacology Ligand 4194 Ansaid®, Froben®
fluticasone Approved drug Immunopharmacology Ligand 6699 Advair®, Avamys®, Flovent HFA®, Veramyst®
fluticasone furoate Approved drug PDB Ligand Immunopharmacology Ligand 10892 Arnuity Ellipta, Avamys, FF, Flonase Sensimist, Veramyst
fluticasone propionate Approved drug Immunopharmacology Ligand 7080 Advair Diskus®, ArmonAir RespiClickTM, CCI-18781, Flovent®
fluvoxamine Approved drug PDB Ligand Immunopharmacology Ligand 7189 Luvox®, U-23000
FLX475 Immunopharmacology Ligand 12153 example 43 [WO2018022992A1], FLX-475
formoterol Approved drug Immunopharmacology Ligand 3465 BD-40A, CGP-25827A, Foradil®, Oxeze/Oxis®, YM-08316
fosdagrocorat Immunopharmacology Ligand 9649 PF-04171327
fosifidancitinib Immunopharmacology Ligand 10637
fosizensertib Immunopharmacology Ligand 13806 compound 19 [WO2023018643A1]
fostamatinib Approved drug PDB Ligand Immunopharmacology Ligand 7796 R 788, R-788, R7935788, Tavalisse®, Tavlesse®
FR122047 Immunopharmacology Ligand 5191 FR 122047, FR 122047 hydrochloride, FR-122047
friluglanstat Immunopharmacology Ligand 12888 example 11 [US9216968B2]
 
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gabapentin Approved drug PDB Ligand Immunopharmacology Ligand 5483 CI 945, Go 3450, GOE 2450, GOE 3450, Neurontin®
Galapagos MAPKAPK5 inhibitor D Immunopharmacology Ligand 9848 compound 183 [WO2007138072A2]
gamcemetinib Immunopharmacology Ligand 12167 CC-99677, CC99677
gandotinib PDB Ligand Immunopharmacology Ligand 7909 LY-2784544, LY2784544
GB88 Immunopharmacology Ligand 6658 GB 88, GB-88
GDC-0214 Immunopharmacology Ligand 12318 GDC0214, iJak-381, RG-6151, RG6151
GDC-0834 PDB Ligand Immunopharmacology Ligand 9263 GDC 0834
GDC-2394 PDB Ligand Immunopharmacology Ligand 12280 compound 20 [PMID: 36279149], GDC2394
gefapixant Approved drug PDB Ligand Immunopharmacology Ligand 9540 AF-219, AF219, Lyfnua®, MK7264, MK‐7264
GlcC14C18 Immunopharmacology Ligand 9483 6-O-(2'(R,S)-tetradecyloctadecanoyl)-D-glucose
glibenclamide Approved drug PDB Ligand Immunopharmacology Ligand 2414 Amglidia®, Diabeta®, glyburide, Glynase®
GLPG0974 Immunopharmacology Ligand 8417 compound 99 [PMID 25380412]
GLPG1205 Immunopharmacology Ligand 10171 compound 122 [WO2013092791A1], GLPG-1205
GLPG3970 Immunopharmacology Ligand 12157 compound 32 [PMID: 38552030], compound 88 [WO2019238424A1], GLPG-3970
glycopyrrolate Approved drug Immunopharmacology Ligand 7459 AHR-504, Qbrexza® (glycopyrronium cloth), Robinul®, Seebri Neohaler®, Tovanor Breezhaler®
GNE-3500 Immunopharmacology Ligand 9660
GNE-4997 PDB Ligand Immunopharmacology Ligand 9995 compound 28 [PMID: 25844760], GNE 4997, GNE4997
GNE684 PDB Ligand Immunopharmacology Ligand 13107 GNE-684
GNF362 Immunopharmacology Ligand 9548 example 71 [US20090306039]
GR-389988 Immunopharmacology Ligand 10257 Ex. 3-15 [US9174986B2], GR389988, GZ389988, GZ389988A
Grp94 inhibitor 54 Immunopharmacology Ligand 10118
GSK065 PDB Ligand Immunopharmacology Ligand 10358 GSK3335065, inhibitor C1 [PMID: 28604669]
GSK143 Immunopharmacology Ligand 9388 compound 20 [PMID: 21903390]
GSK1482160 PDB Ligand Immunopharmacology Ligand 10504 compound 1b [PMID: 31525963], compound 31 [PMID: 20673717], GSK-1482160
GSK2245035 Immunopharmacology Ligand 9254 compound 32 [PMID: 26861551]
GSK2256294 Immunopharmacology Ligand 9718 GSK-2256294, GSK-2256294A, GSK2256294A
GSK2292767 PDB Ligand Immunopharmacology Ligand 10633 compound 2 [PMID: 30532965], compound 3 [PMID: 26301626], GSK-2292767
GSK2646264 PDB Ligand Immunopharmacology Ligand 10108 compound 44 [PMID: 30249354]
GSK2879552 Immunopharmacology Ligand 9116 Example 26 [WO2012135113], GSK-2879552
GSK2981278 Immunopharmacology Ligand 9661
GSK2982772 PDB Ligand Immunopharmacology Ligand 9554 compound 5 [PMID: 28151659]
GSK343 PDB Ligand Immunopharmacology Ligand 8240 compound 6 [PMID 24900432], GSK 343
GSK'547 Immunopharmacology Ligand 11274 example 6 [WO2020044206A1], GSK-547, GSK547
GSK583 PDB Ligand Immunopharmacology Ligand 9134 GSK'583
GSK8612 Immunopharmacology Ligand 10343
GSK866 PDB Ligand Immunopharmacology Ligand 9653
GSK963 Immunopharmacology Ligand 10132 GSK'963, GSK′963A
GSK2239633A Immunopharmacology Ligand 10416 compound 6 [PMID: 23409871], GSK-2239633A
GSK-7975A Immunopharmacology Ligand 10088 example 36 [US20120053150A1], GSK7975A
GSK-J1 PDB Ligand Immunopharmacology Ligand 7027
GSK-J4 Immunopharmacology Ligand 8979 GSK J4, GSKJ4
gusacitinib Immunopharmacology Ligand 10000 ASN-002, ASN002, example 189 [WO2013028818A1]
GW274150 Immunopharmacology Ligand 9849 [2-[(1-iminoethyl) amino]ethyl]-L-homocysteine, GW-274150
GW3965 PDB Ligand Immunopharmacology Ligand 2754 C473027, GW 3965, GW-3965
GW406381 Immunopharmacology Ligand 9850 compound 8 [PMID: 15454242], GW-406381
GW 627368 Immunopharmacology Ligand 1953 GW-627368, GW627368, saccharic acid
GW766994 Immunopharmacology Ligand 9680 GSK766994, GW-766994
GYY4137 parent molecule Immunopharmacology Ligand 9808 GYY4137
 
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H-151 Immunopharmacology Ligand 10122 H 151, H151
H4 antagonist 48 Immunopharmacology Ligand 9879
HG-9-91-01 PDB Ligand Immunopharmacology Ligand 8049 HY-15776
HTMT Immunopharmacology Ligand 1273 histamine-trifluoromethyl-toluidine, histamine-trifluoromethyltoluide, HTFMT
hydroxychloroquine Approved drug Immunopharmacology Ligand Antimalarial Ligand 7198 Dolquine®, Plaquenil®
5-hydroxyindoleacetic acid PDB Ligand Immunopharmacology Ligand 11900
hydroxyzine Approved drug Immunopharmacology Ligand 7199 Atarax®, hydroxyzine hydrochloride, hydroxyzine pamoate, Vistaril®
 
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iberdomide PDB Ligand Immunopharmacology Ligand 9618 CC-220, compound 6 [PMID: 28425720]
ibrutinib Approved drug PDB Ligand Immunopharmacology Ligand 6912 Imbruvica®, PCI-32765
ibudilast Approved drug PDB Ligand Immunopharmacology Ligand 7399 AV-411, KC-404, Ketas®, MN-166
ibuprofen Approved drug Immunopharmacology Ligand 2713 Advil®, Brufen®, ibuprofen lysine, ibuprofen sodium, Motrin®, Nurofen®, U-18573
I-C11 Immunopharmacology Ligand 10374
IC-87114 PDB Ligand Immunopharmacology Ligand 9376 IC87114
icanbelimod PDB Ligand Immunopharmacology Ligand 12098 compound 2 [WO2015039587A1], S1p-receptor-agonist-1, YUN88562
IcatCXPZ-01 Immunopharmacology Ligand 11179 compound 8a [PMID: 30978322], XPZ-01
idelalisib Approved drug PDB Ligand Immunopharmacology Ligand 6741 CAL-101/CAL101, GS-1101, Zydelig®
ifidancitinib Immunopharmacology Ligand 10638 A-301, ATI-50002, ATI-502
iguratimod Approved drug PDB Ligand Immunopharmacology Ligand 9736 Careram®, Iremod, Kolbet®, T-614
IKK-beta inhibitor R-28 Immunopharmacology Ligand 10134 (R)-28, example 225 [US8372875B2]
IKK-2 inhibitor IV PDB Ligand Immunopharmacology Ligand 5986 TPCA-1, TPCA1
iloprost Approved drug Immunopharmacology Ligand 1895 Aurlumyn®, Ventavis®
imaradenant PDB Ligand Immunopharmacology Ligand 11153 AZD-4635, AZD4635
imatinib Approved drug PDB Ligand Immunopharmacology Ligand 5687 CGP 57148, Gleevec®, Glivec®, STI571
imetit PDB Ligand Immunopharmacology Ligand 1250
imiquimod Approved drug PDB Ligand Immunopharmacology Ligand 5003 Aldara®, R837, S-26308, Zyclara®
immepip PDB Ligand Immunopharmacology Ligand 1251
impromidine Immunopharmacology Ligand 1226 SK&F-92676-A3
INCB3284 Immunopharmacology Ligand 9045 compound 13 [PMID: 24900329], INCB 3284
INCB8761 Immunopharmacology Ligand 9032 compound 17 [PMID: 24900280], INCB-8761, PF-4136309, PF4136309
indacaterol Approved drug Immunopharmacology Ligand 7455 Arcapta Neohaler®, Onbrez®, QAB-149, QAB149
indole-3-carbinol PDB Ligand Immunopharmacology Ligand 10047 3-hydroxymethylindole, 3-indolemethanol, 3-indolylcarbinol, I3C
indomethacin Approved drug PDB Ligand Immunopharmacology Ligand 1909 Indocid®, Indocin®
inhibitor M9 [PMID: 38236416] Immunopharmacology Ligand 13113
inhibitor 32 [PMID: 29620892] Immunopharmacology Ligand 9898
ipratropium Approved drug Immunopharmacology Ligand 325 Atrovent®, Ipraxa®
iptacopan Approved drug PDB Ligand Immunopharmacology Ligand 10710 compound 41 [PMID: 32073845], Fabhalta®, LNP-023, LNP023
IRAK-1/4 inhibitor Immunopharmacology Ligand 5990
IRAK4 inhibitor 4b [PMID: 18474425] PDB Ligand Immunopharmacology Ligand 8080
IRAK4 inhibitor rac-45 [PMID: 18501603] Immunopharmacology Ligand 8081
ISO-1 Immunopharmacology Ligand 9984 IN1228
isoetarine Approved drug Immunopharmacology Ligand 7205 Bronkometer®, Bronkosol®, WIN-3406
isothiourea-1t PDB Ligand Immunopharmacology Ligand 2899 IT1t
itacitinib PDB Ligand Immunopharmacology Ligand 8364 Examlpe 294 [WO2011112662], INCB-039110
ivarmacitinib Immunopharmacology Ligand 11878 example 34 [WO2013091539A1], SHR-0302, SHR0302
izencitinib Immunopharmacology Ligand 10458 example 1 [WO2016191524A1], JNJ-8398, JNJ8398, TD-1473, TD1473
 
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JAK3 inhibitor 32 Immunopharmacology Ligand 10156 compound 32 [PMID: 30423248]
JAK3 inhibitor 34 PDB Ligand Immunopharmacology Ligand 10157 compound 34 [PMID: 30423248]
JAK inhibitor 20a Immunopharmacology Ligand 10147
JAK inhibitor 17b Immunopharmacology Ligand 10148
JNJ-10191584 Immunopharmacology Ligand 1277 compound 12, JNJ 10191584, VUF 6002, VUF6002
JNJ-10311795 Immunopharmacology Ligand 6563
JNJ-27141491 Immunopharmacology Ligand 10586 JNJ27141491
JNJ-39758979 Immunopharmacology Ligand 8984 JNJ 39758979, JNJ39758979
JNK inhibitor IX Immunopharmacology Ligand 5996 AC1LG8KT, BAS 01816608, TCS JNK 5a
JR14a Immunopharmacology Ligand 10595
 
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KA1010 Immunopharmacology Ligand 9663
KBP-7018 Immunopharmacology Ligand 9691 compound 3 [Huang et al., 2017]
ketoprofen Approved drug Immunopharmacology Ligand 4795 Actron®, Orudis®
ketorolac Approved drug Immunopharmacology Ligand 6661 Acular®, Toradol®
KML29 Immunopharmacology Ligand 9482
KT-109 Immunopharmacology Ligand 10245 KT109
KT-474 Immunopharmacology Ligand 12892 Compound A [WO2022174269A1], KT474
 
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L-798,106 Immunopharmacology Ligand 1941 L-798106, L798106
labuxtinib Immunopharmacology Ligand 12870 Compound 1 [WO2022109595], example F91 [WO2013033070], THB-335, THB335
lanraplenib PDB Ligand Immunopharmacology Ligand 9764 compound 39 [PMID: 32292557], Ex.-2, US9290505, example 2 [US9290505], GS-9876, GS9876
LASSBio-1524 Immunopharmacology Ligand 11066
LASW1393 PDB Ligand Immunopharmacology Ligand 10527 compound 34 [PMID: 31609613], LASW-1393
lazucirnon Immunopharmacology Ligand 10653 AKST-4290, AKST4290, ALK-4290, ALK4290, Example 11 [WO2012045803A1]
leflunomide Approved drug Immunopharmacology Ligand 6825 Arabloc®, Arava®, HWA 486, HWA-486, lefunamide, SU-101
lenabasum PDB Ligand Immunopharmacology Ligand 9772 ajulemic acid, CPL-7075, CPL7075, CT-3, IP-751, IP751
lenalidomide Approved drug Immunopharmacology Ligand 7331 CC-5013, CDC-501, Revlimid®
leniolisib Approved drug PDB Ligand Immunopharmacology Ligand 9424 CDZ-173, CDZ173, Example 67 [WO2012004299], Joenja®
LEO 134310 Immunopharmacology Ligand 11901 LEO-134310, LEO134310
LEO 239652 PDB Ligand Immunopharmacology Ligand 12725 compound 40 [PMID: 33054196], LEO-239652, LEO239652
LEO 29102 Immunopharmacology Ligand 12724 compound 20 [PMID: 24984230], LEO-29102, LEO29102
L-161,982 (EP4A) Immunopharmacology Ligand 1952 EP4A, L-161982, L161982
lepzacitinib Immunopharmacology Ligand 12871 example 117 [WO2019090158A1]
lestaurtinib PDB Ligand Immunopharmacology Ligand 5672 CEP-701, KT-5555, SP924
levosalbutamol Approved drug PDB Ligand Immunopharmacology Ligand 9816 (-)-albuterol, (-)-salbutamol, (R)-salbutamol, levalbuterol, Xopenex®
LFM-A13 Immunopharmacology Ligand 9262 α-cyano-beta-hydroxy-β-methyl-N-(2, 5-dibromophenyl)propenamide, alpha-cyano-beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl)propenamide
L6H21 Immunopharmacology Ligand 9027
LHVS Immunopharmacology Ligand 9298 morpholinurea-leucine-homophenylalanine-vinylsulfone-phenyl, morpholinurea-leucine-homophenylalaninevinyl phenyl sulfone
lifitegrast Approved drug Immunopharmacology Ligand 7533 compound 1g [PMID: 24900456], SAR 1118, SAR-1118, SAR-1118-023, Xiidra®
linrodostat Immunopharmacology Ligand 9707 BMS-986205, BMS986205, Compound 2 [PMID: 29531094], Example 19 [US20160137652A1]
lisofylline Immunopharmacology Ligand 9225 (R)-lisophylline, CT-1501R
LIT-927 Immunopharmacology Ligand 10075 compound 57 [PMID: 30106292]
LM10 Immunopharmacology Ligand 9016 LM-10
lodoxamide Approved drug PDB Ligand Immunopharmacology Ligand 9743 Alomide®
lomedeucitinib Immunopharmacology Ligand 13210 BMS-986322, BMS986322, example 252 [US20210253554]
londamocitinib Immunopharmacology Ligand 11716 AZD-4604, AZD4604, example 35 [WO2018134213A1], Jak1-IN-7
lonodelestat Immunopharmacology Ligand 11275 cyclo[Ala-Ser-Ile-Pro-Pro-Gln-Lys-Tyr-D-Pro-Pro-Nle(Bu)-Glu-Thr], POL-6014, POL6014
loratadine Approved drug Immunopharmacology Ligand 7216 Claritin®, SCH-29851
lorecivivint Immunopharmacology Ligand 9620 adavivint (deprecated INN), SM0-4690, SM04690
losmapimod Immunopharmacology Ligand 7835 GS856553, GW856553
5-LOX inhibitor 2m [PMID: 30199704] Immunopharmacology Ligand 10079
lumiracoxib Approved drug PDB Ligand Immunopharmacology Ligand 2897 Prexige®
LW106 Immunopharmacology Ligand 9940
LX2931 Immunopharmacology Ligand 9851 LX3305
LY255283 Immunopharmacology Ligand 3351 CGS 23356, LY 255283, LY-255283
LY3023703 PDB Ligand Immunopharmacology Ligand 12211 compound 9 [PMID: 25260492]
LY3509754 Immunopharmacology Ligand 13164
LYS006 PDB Ligand Immunopharmacology Ligand 11205 LYS-006
 
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3M-002 PDB Ligand Immunopharmacology Ligand 9270 CL-075, CL075
MAPK13-IN-1 PDB Ligand Immunopharmacology Ligand 11096 compound 61 [WO2014015056A2]
mapracorat Immunopharmacology Ligand 9654 BOL-303242-X, ZK-245186, ZK245186
maraviroc Approved drug Immunopharmacology Ligand 806 Celsentri®, Selzentry®, UK 427857, UK-427,857
marbostat-100 Immunopharmacology Ligand 9891 compound 5a [PMID: 29589441]
maresin 1 Immunopharmacology Ligand 12056 7R,14S-dihydroxydocosa-4Z,8E,10E,12Z,16Z,19Z-hexaenoic acid, 7R-Maresin 1, MaR1, Maresin-1
maresin 2 Immunopharmacology Ligand 12055 13R,14S-diHDHA, 13R,14S-dihydroxy-docosahexaenoic acid, MaR2, maresin-2
masitinib PDB Ligand Immunopharmacology Ligand 5656 AB-1010, AB1010, Masican® (proposed trade name)
mavorixafor Approved drug PDB Ligand Immunopharmacology Ligand 8580 AMD 070, AMD-070, AMD-11070, AMD11070, compound 2 [PMID: 20297846], X4P-001, X4P-001-IO, X4P-001-LD, Xolremdi®
MCC950 PDB Ligand Immunopharmacology Ligand 8228 CP-456,773, CP-456773, CRID3, MCC-950
MDG 548 Immunopharmacology Ligand 9888 compound 1 [PMID: 22582973], MDG-548, MDG548
meclofenamic acid Approved drug PDB Ligand Immunopharmacology Ligand 7219 CL-583, INF-4668, Meclomen®
mefenamic acid Approved drug PDB Ligand Immunopharmacology Ligand 2593 CI-473, CN-35355, INF-3355, Ponstan®, Ponstel®
meloxicam Approved drug PDB Ligand Immunopharmacology Ligand 7220 Mobic®, UHAC-62XX
mepacrine PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 10172 Atabrine®, quinacrine
mepyramine Approved drug PDB Ligand Immunopharmacology Ligand 1227 Anthisan®, mepiramine, mepyramine maleate, pyrilamine, pyrilamine tannate, Pyrlex®
merestinib PDB Ligand Immunopharmacology Ligand 9841 LY-2801653, LY2801653
mesalazine Approved drug Immunopharmacology Ligand 2700 5-aminosalicylic acid, 5-ASA, mesalamine (USAN), Pentasa®
metformin Approved drug PDB Ligand Immunopharmacology Ligand 4779 Glucophage®, LA-6023
methacholine Approved drug Immunopharmacology Ligand 7438 methacholine bromide, Provocholine®
methimazole Approved drug PDB Ligand Immunopharmacology Ligand 6649 Tapazole®, Thiamazole®
methotrexate Approved drug PDB Ligand Immunopharmacology Ligand 4815 Abitrexate®, amethopterin, Nordimet®, Rasuvo®
(R)-α-methylhistamine Immunopharmacology Ligand 1236 (R)-α-MeHA, alpha-methylhistamine
MIDD0301 Immunopharmacology Ligand 9890
midostaurin Approved drug PDB Ligand Immunopharmacology Ligand 5702 CGP 41231, CGP 41251, N-benzoylstaurosporine, PKC412, Rydapt®
mifepristone Approved drug PDB Ligand Immunopharmacology Ligand 2805 Mifeprex®, RU-486, RU486
MIF inhibitor 3bb PDB Ligand Immunopharmacology Ligand 9986
milategrast Immunopharmacology Ligand 10463 example 9 [US20050261291A1]
miltefosine Approved drug Immunopharmacology Ligand 11355 D-18506, D18506, Impavido®, Miltex®, n-hexadecylphosphorylcholine
mivavotinib PDB Ligand Immunopharmacology Ligand 9600 compound 3b [PMID: 27839918], TAK-659, TAK659
mizolastine Approved drug Immunopharmacology Ligand 10102 Mizollen®, MKC-431, MKC431, SL 85.0324, SL-850324, SL850324
MK-0359 Immunopharmacology Ligand 9852 L-454,560, L-454560, MK0359
MK-0812 Immunopharmacology Ligand 9048 MK0812
MK-0873 Immunopharmacology Ligand 9853 compound 20 [PMID: 18835163], MK0873
MK-886 PDB Ligand Immunopharmacology Ligand 2655 L 663536, MK886
ML130 Immunopharmacology Ligand 8887 compound 1c [PMID: 22003428], ML-130, Noditinib-1
ML324 Immunopharmacology Ligand Antimalarial Ligand 9584 ML-324, MMV1580488
MLN-120B Immunopharmacology Ligand 5694 ML120B, MLN120B
ML2-SA1 Immunopharmacology Ligand 10301 EVP-22, EVP22, ML2 SA1, ML2SA1
MM-433593 Immunopharmacology Ligand 9944 MM433593
mocravimod Immunopharmacology Ligand 9727 compound 2 [PMID: 23124563], KRP-203, KRP203
mocravimod-phosphate Immunopharmacology Ligand 2923 KRP 203-phosphate, KRP203-phosphate
mofegiline Immunopharmacology Ligand 9754 MDL 72974, MDL-72,974, MDL-72974A
molibresib PDB Ligand Immunopharmacology Ligand 7033 CS-0717, GSK 525762A, GSK-525762, GSK525762, I-BET-762, I-BET762
mometasone Approved drug Immunopharmacology Ligand 9029 Elocon® (topical), Nasonex®
monomethyl fumarate PDB Ligand Immunopharmacology Ligand 5786 methyl hydrogen fumarate
montelukast Approved drug PDB Ligand Immunopharmacology Ligand 3340 Singulair®
mosedipimod Immunopharmacology Ligand 9771 EC-18, Plag, (+/-)
motolimod Immunopharmacology Ligand 9026 VTX-2337
MPI-0485520 Immunopharmacology Ligand 9580 MPC-9528, MPI-485520
MPPA Immunopharmacology Ligand 9897 inhibitor 23 [PMID: 29614224]
MRI-1867 Immunopharmacology Ligand 10521 (-)-MRI-1867, MRI1867
MRL-248 Immunopharmacology Ligand 9080
MRL-367 Immunopharmacology Ligand 9079
MRL-871 PDB Ligand Immunopharmacology Ligand 10642 MRL871
MRS2578 Immunopharmacology Ligand 1753 MRS 2578, MRS-2578
MRS4458 Immunopharmacology Ligand 9998 compound 20 [Yu et al., 2018]
MRS4478 Immunopharmacology Ligand 9999 compound 30 [Yu et al., 2018]
MRT67307 PDB Ligand Immunopharmacology Ligand 8062 MRT-67307
MW150 PDB Ligand Immunopharmacology Ligand 10524 compound 11 [PMID: 30978288], compound 27 [WO2014145485A2], compound 8 [PMID: 25676389], MW-150, MW01-18-150SRM
mycophenolate mofetil Approved drug Immunopharmacology Ligand 6831 Cellcept®, RS-61443, RS-61443-190
 
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nabumetone Approved drug PDB Ligand Immunopharmacology Ligand 7245 BRL-14777, Relafen®
nacresertib Immunopharmacology Ligand 13502 compound 001 [WO2021057785]
naproxcinod Immunopharmacology Ligand 9551 AZD-3582, AZD3582, HCT-3012, NO-naproxen
naproxen Approved drug PDB Ligand Immunopharmacology Ligand 5230 (S)-naproxen, Aleve®, Naprosy®
navamepent Immunopharmacology Ligand 9463 RX-10045
navarixin Immunopharmacology Ligand 8497 MK-7123, MK7123, SCH-527123, SCH527123
navoximod PDB Ligand Immunopharmacology Ligand 9019 GDC-0919, NLG-919, NLG919, RG6078
NBI-74330 Immunopharmacology Ligand 839 (±)-NBI 74330, NBI74330
NC1 Immunopharmacology Ligand 10373
NCX-4016 Immunopharmacology Ligand 9018 NCX 4016, NCX4016, nitric oxide-releasing aspirin, nitroaspirin
ND-2110 PDB Ligand Immunopharmacology Ligand 8082
ND-2158 Immunopharmacology Ligand 8083
NDT-19795 Immunopharmacology Ligand 13009 NDT19795
NDT9513727 PDB Ligand Immunopharmacology Ligand 9746 NDT 9513727, NDT-9513727
necrostatin-1 Immunopharmacology Ligand 9750 methyl-thiohydantoin-tryptophan, MTH-DL-tryptophan, MTH-trp, nec-1, Necrostatin 1
necrostatin-1s Immunopharmacology Ligand 9751 7-Cl-O-Nec-1, nec-1s, necrostatin 2 racemate
nedocromil Approved drug Immunopharmacology Ligand 7607 FPL-59002, nedocromil sodium, Rapitil®, Tilade®
neflamapimod PDB Ligand Immunopharmacology Ligand 5719 VD-31745, VRT-031745, VX 745, VX-745
nemiralisib PDB Ligand Immunopharmacology Ligand 9425 compound 2 [PMID: 26301626], GSK-2269557, GSK2269557
neoceptin-3 PDB Ligand Immunopharmacology Ligand 9137
neoceptin-4 Immunopharmacology Ligand 9138
NE 52-QQ57 Immunopharmacology Ligand 10206 example 35 [WO2012131633A1], GPR4 antagonist 13, NE52-QQ57
nerandomilast Immunopharmacology Ligand 12518 BI 1015550, BI-1015550, BI1015550
α-NETA Immunopharmacology Ligand 9781
Nexinhib20 Immunopharmacology Ligand 9419
nezulcitinib Immunopharmacology Ligand 11304 example 1 [WO2020051105A1]
NF-56-EJ40 PDB Ligand Immunopharmacology Ligand 10519
nibrozetone Immunopharmacology Ligand 13184 ABDNAZ, RRx-001, RRx001
niflumic acid Approved drug PDB Ligand Immunopharmacology Ligand 2439
NIK inhibitor 12f Immunopharmacology Ligand 10947
NIK SMI1 Immunopharmacology Ligand 9964
nimesulide Approved drug PDB Ligand Immunopharmacology Ligand 7401 R-805
N-methyl-2-pyrrolidone PDB Ligand Immunopharmacology Ligand 9520 NMP, N-methyl-pyrrolidone
6-n-octylaminouracil Immunopharmacology Ligand 5846 6-n-octyl aminouracil
NP3-253 PDB Ligand Immunopharmacology Ligand 13645 compound 16 [PMID: 39574318], NP3253
NPT520-34 Immunopharmacology Ligand 13271 compound 1 [WO2019246454]
NS-398 PDB Ligand Immunopharmacology Ligand 8976 NS 398
NS6180 Immunopharmacology Ligand 9318
NS6740 Immunopharmacology Ligand 11383 A-793394, A793394, NS-6740
NSC61610 Immunopharmacology Ligand 10364
NSC80734 Immunopharmacology Ligand 10497
NT-0249 Immunopharmacology Ligand 13338 NT0249
NT-0796 Immunopharmacology Ligand 13008 NT0796
NX-2127 Immunopharmacology Ligand 12519
NX-5948 Immunopharmacology Ligand 12898 compound 195 [WO2021113557A1], NX5948
 
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obatoclax Immunopharmacology Ligand 11086 GX-15-070, GX15-070, obatoclax mesylate, SB16622
ocadusertib Immunopharmacology Ligand 13504 compound I-30 [WO2021046407], LY-3871801, LY3871801, R-552, R552
oclacitinib Immunopharmacology Ligand 9696 Apoquel® (veterinary use), PF-03394197
17-octadecynoic acid Immunopharmacology Ligand 8851 17-ODYA
OD36 PDB Ligand Immunopharmacology Ligand 10406
ofirnoflast Immunopharmacology Ligand 13227 example 10 [WO2021242505]
olaptesed pegol Immunopharmacology Ligand 9674 NOX-A12
olinciguat Immunopharmacology Ligand 10213 IW-1701, IW1701
olodaterol Approved drug PDB Ligand Immunopharmacology Ligand 7543 BI-1744, BI-1744-CL, Striverdi®
olopatadine Approved drug Immunopharmacology Ligand 7249 ALO-4943A, KW-4679, Opatanol®, Patanol®, Pazeo®
olverembatinib Approved drug PDB Ligand Immunopharmacology Ligand 10630 compound 10a [PMID: 23301703], GZD-824, GZD824, HQP-1351, HQP1351
omaveloxolone Approved drug Immunopharmacology Ligand 7573 RTA 408, RTA-408, Skyclarys®
4-OMe-ARM1 PDB Ligand Immunopharmacology Ligand 10562 compound 7 [PMID: 31751136]
omilancor Immunopharmacology Ligand 10363 analogue 7 [PMID: 27933891], BT-11, BT11, Example 1 [US9556146B2]
omipalisib PDB Ligand Immunopharmacology Ligand 8974 GSK 2126458, GSK-2126458, GSK2126458
ONC201 Immunopharmacology Ligand 9978 ONC-201, TIC-10, TIC10
ONO-AE3-208 Immunopharmacology Ligand 1942 ONO AE3 208
ONX-0914 Immunopharmacology Ligand 9031 PR-957
orelabrutinib Approved drug Immunopharmacology Ligand 10629 example 3 [WO2015048662A2], ICP-022, ICP022
ORG 214007-0 Immunopharmacology Ligand 11310 [(-)-N-(2S,10S,14bS)]-N-(8-cyano-1,2,3,4,10,14b-hexahydro-10-methyl dibenzo[c,f]pyrido[1,2-a]azepin-2-yl)-4-methyl-1,2,3-thiadiazole-5-carboxamide]], ORG214007-0
Orita-13 PDB Ligand Immunopharmacology Ligand 9985 compound 13 [PMID: 11170644]
otenaproxesul Immunopharmacology Ligand 9534 ATB 346, ATB-346, ATB-346, (S)-, ATB346
oxaprozin Approved drug PDB Ligand Immunopharmacology Ligand 7252 Daypro®, WY-21743
ozagrel Approved drug Immunopharmacology Ligand 9866 Cataclot®, KCT-0809, OKY-046, Pulmoza®
ozanimod Approved drug PDB Ligand Immunopharmacology Ligand 8709 RPC-1063, RPC1063, Zeposia®
 
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P505-15 PDB Ligand Immunopharmacology Ligand 8070 BIIB057, PRT-062607, PRT062607
pamapimod PDB Ligand Immunopharmacology Ligand 9915 compound 2b [PMID: 21375264], Ro 4402257, Ro-4402257, Ro4402257
parecoxib Approved drug PDB Ligand Immunopharmacology Ligand 2895 Dynastat®, SC-69124
parsaclisib Immunopharmacology Ligand 10098 compound 20 [PMID: 31749910], IBI376, INCB-050465
PBF-509 Immunopharmacology Ligand 10193 PBF509
PBT-3 Immunopharmacology Ligand 9755
PCA 4248 Immunopharmacology Ligand 6080 PCA-4248, PTEMC
PDE4 inhibitor 16 PDB Ligand Immunopharmacology Ligand 10400
pecazine Approved drug Immunopharmacology Ligand 9782 mepazine, nothiazine, Pacatal®
peficitinib Approved drug Immunopharmacology Ligand 8315 ASP015K, JNJ-54781532
pelubiprofen Immunopharmacology Ligand 9876 compound 13b [PMID: 6607354], CS-670, DW-330SR, DW330SR, RS-2131
penicillamine Approved drug PDB Ligand Immunopharmacology Ligand 7264 Cuprimine®
peptide 1 [PMID: 31774287] Immunopharmacology Ligand 10594
petesicatib Immunopharmacology Ligand 9855 RG-7625, RG7625, RO-5459072
PF-03715455 PDB Ligand Immunopharmacology Ligand 8179
PF-04191834 Immunopharmacology Ligand 9054 PF 4191834, PF-4191834
PF-04418948 Immunopharmacology Ligand 5817 PF 04418948, PF04418948
PF-04634817 Immunopharmacology Ligand 9979 example 13 [US8293903], PF-4634817, PF04634817, PF4634817
PF-04859989 Immunopharmacology Ligand 9038 compound 1 [PMID: 23466229]
PF-04905428 Immunopharmacology Ligand 9062 CE-224,535, CE-224535, compound 3 [PMID: 21782426], compound 33 [PMID: 21565499]
PF-04957325 Immunopharmacology Ligand 9659
PF-06263276 PDB Ligand Immunopharmacology Ligand 9432 compound 2 [PMID: 27983835], PF 0626327, PF0626327
PF-06282999 Immunopharmacology Ligand 10053 compound 8 [PMID: 26509551], PF06282999
PF-06426779 Immunopharmacology Ligand 9666 example 189 [WO2015150995], example 38 [PMID:28498658]
PF-06840003 Immunopharmacology Ligand 9565 EOS200271, PF06840003
PF‐06928215 Immunopharmacology Ligand 11324
PF-07038124 Immunopharmacology Ligand 11950 Example 4 [US2020108083A1], PF07038124
PF-07054894 Immunopharmacology Ligand 12765 PF07054894
PF-152 Immunopharmacology Ligand 9014 compound 43a, example 64 [WO2009016498], PF152
PFK15 Immunopharmacology Ligand 9562 PFK-015
PH-797804 PDB Ligand Immunopharmacology Ligand 7818
PHA-408 Immunopharmacology Ligand 9398 PHA408
phenylbutazone Approved drug PDB Ligand Immunopharmacology Ligand 7270 Butazolidine®
piclamilast PDB Ligand Immunopharmacology Ligand 11627 RP 73401, RP-73-401, RP73401
piclidenoson PDB Ligand Immunopharmacology Ligand 422 IB-MECA, CF 101, CF101, N(6)-ibamu
pirfenidone Approved drug Immunopharmacology Ligand 7532 AMR-69, Esbriet®
piroxicam Approved drug Immunopharmacology Ligand 7273 CP-16171, Feldene®
pirtobrutinib Approved drug PDB Ligand Immunopharmacology Ligand 11628 BTK inhibitor 16, Jaypirca®, LOXO-305, LOXO305, MCL-133, MCL133, RXC005
pixatimod Immunopharmacology Ligand 9870 compound 18 [PMID: 22458531], PG-545, PG545
PJ34 PDB Ligand Immunopharmacology Ligand 11348 PJ-34
PKCθ inhibitor 14 Immunopharmacology Ligand 9452 compound 14 [PMID: 27117263]
PKUMDL_MH_1001 Immunopharmacology Ligand 9141
plerixafor Approved drug PDB Ligand Immunopharmacology Ligand 844 AMD 3100, AMD3100, bicyclam JM-2987, JM 3100, Mozobil®
PLX5622 PDB Ligand Immunopharmacology Ligand 9105 PLX 5622, PLX-5622
PLX7486 Immunopharmacology Ligand 9104 OPN 7486, OPN-7486, PLX-7486
(S)-23 [PMID: 27933945] PDB Ligand Immunopharmacology Ligand 9796
PN10 Immunopharmacology Ligand 10089
PO-322 Immunopharmacology Ligand 10739 1H-indole-2,3-dione 3-(1,3-benzoxazol-2-ylhydrazone), PO322
polmacoxib Approved drug PDB Ligand Immunopharmacology Ligand 8316 Acelex® (S. Korea), CG-100649, CG100649
pomalidomide Approved drug Immunopharmacology Ligand 7348 CC-4047, IMID-3, Imnovid®, Pomalyst®
POM2-C-HMBP Immunopharmacology Ligand 9616
ponatinib Approved drug PDB Ligand Immunopharmacology Ligand 5890 AP24534, Iclusig®
ponesimod Approved drug Immunopharmacology Ligand 9320 ACT-128800, ACT128800, Compound 8bo [PMID:20446681], Ponvory®
poseltinib Immunopharmacology Ligand 9862 Example 228 [WO2011162515A2], HM71224, HM‐71224, LY333764
povorcitinib Immunopharmacology Ligand 11881 compound 7 [US20210238168A1]
PP2 Immunopharmacology Ligand 9404
PQA-18 Immunopharmacology Ligand 9454
praliciguat Immunopharmacology Ligand 9900 IW-1973, IW1973
pralnacasan Immunopharmacology Ligand 6467 VX-740, VX740
pranlukast Approved drug PDB Ligand Immunopharmacology Ligand 3634 ONO RS-411
prednicarbate Approved drug Immunopharmacology Ligand 7605 Dermatop®, Hoe 777, Hoe-777, S-770777
prednisolone Approved drug PDB Ligand Immunopharmacology Ligand 2866 DELTA.1-Cortisol, Orapred®, Pediapred®
prednisone Approved drug Immunopharmacology Ligand 7096 Lodotra®, Sterapred®
preladenant Immunopharmacology Ligand 5614 SCH-420814, SCH420814
PRN694 Immunopharmacology Ligand 9285
procaterol Approved drug Immunopharmacology Ligand 3464
proximod Immunopharmacology Ligand 13783 compound 53b [Tian et al., 2013], IMMH001, LJR001, SYL930
PSB1115 Immunopharmacology Ligand 3286 compound 17 [PMID: 11906291], PSB 1115, PSB-1115
PSB-17365 Immunopharmacology Ligand 9871 compound 48 [Pillaiyar et al., 2018], PSB17365
PSB-KD107 Immunopharmacology Ligand 11081 compound 2Ak [PMID: 17827019], compound 5 [Schoeder et al., 2020]
psora-4 Immunopharmacology Ligand 9583 5-(4-phenylbutoxy)psoralen, psora 4
PXS-4681A Immunopharmacology Ligand 9753
PXS-4728A Immunopharmacology Ligand 9346 PXS4728A
P2Y14R antagonist I-17 Immunopharmacology Ligand 13422 compound I-17 [PMID: 38874515]
2-pyridylethylamine Immunopharmacology Ligand 1197 PEA
 
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QAV680 Immunopharmacology Ligand 8996 NVP-QAV680
quemliclustat PDB Ligand Immunopharmacology Ligand 10707 AB-680, AB680
 
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1R-11 Immunopharmacology Ligand 10138
R283 Immunopharmacology Ligand 10049 1,3-Dimethyl-2[(oxopropyl)thio]imidazolium
RA839 PDB Ligand Immunopharmacology Ligand 10487 compound 7 [PMID: 31411465], RA-839
rabeximod Immunopharmacology Ligand 9856 Rob-803, Rob803
rebastinib PDB Ligand Immunopharmacology Ligand 9173 DCC 2036, DCC-2036, DP-1919
relacorilant Immunopharmacology Ligand 13830 compound 7 [PMID: 28368581], CORT-125134, CORT125134
remibrutinib Immunopharmacology Ligand 10457 compound 25 [PMID: 32083858], example 6 [WO2015079417A1], LOU-064, LOU064, LOU064-NXA, NVP-LOU064-NXA
reparixin Immunopharmacology Ligand 8498 DF 1681Y, repertaxin
reproxalap Immunopharmacology Ligand 10613 ADX-102, ADX102, example 5 [WO2018039197A1], NS-2, NS2
resatorvid Immunopharmacology Ligand 9036 TAK-242, TAK242
resiquimod PDB Ligand Immunopharmacology Ligand 5051 R-848, R848
[3H]resolvin D1 Ligand is labelled Ligand is radioactive Immunopharmacology Ligand 4356 [3H]-RvD1
[3H]resolvin E1 Ligand is labelled Ligand is radioactive Immunopharmacology Ligand 2901 [(3)H]-labeled RvE1, [3H]RvE1
revamilast Immunopharmacology Ligand 9865 Example 26 [WO2006064355A2], GRC 4039, GRC-4039, GRC4039
RG7112 PDB Ligand Immunopharmacology Ligand 9599
rilapladib Immunopharmacology Ligand 7376 SB 659032
rilzabrutinib PDB Ligand Immunopharmacology Ligand 9993 Example 31 [WO2014039899], PRN-1008, PRN1008
rimacalib Immunopharmacology Ligand 9364 SMP-114
RIPA-56 Immunopharmacology Ligand 9643 compound 56 [PMID: 27992216], compound 92 [WO2016101885]
RIPK2 inhibitor 3 PDB Ligand Immunopharmacology Ligand 10413 compound 3 [PMID: 31265286], Example 1 [WO2014043446A1], GSK2983559
RIPK2 inhibitor 5 PDB Ligand Immunopharmacology Ligand 10419 compound 5 [PMID: 31265286]
RIPK2 inhibitor 8 Immunopharmacology Ligand 9688
RIPK3 inhibitor 18 Immunopharmacology Ligand 10389
RIPK3 inhibitor 42 Immunopharmacology Ligand 10401
ritlecitinib Approved drug Immunopharmacology Ligand 9559 compound 11 [PMID: 28139931], example 5 [WO2015083028], Litfulo®, PF-06651600, PF06651600
Ro26-4550 Immunopharmacology Ligand 5052 Ro 26-4550, Ro-26-4550
rocbrutinib Immunopharmacology Ligand 12875
rofecoxib Approved drug PDB Ligand Immunopharmacology Ligand 2893 Ceoxx®, MK 966, Vioxx®
roflumilast Approved drug PDB Ligand Immunopharmacology Ligand 6962 ARQ-151/Zoryve® (roflumilast cream), BY-217, BYK-20869, Daliresp®, Daxas®
roflupram Immunopharmacology Ligand 10691 FFPM, Zl-n-91
rolipram Immunopharmacology Ligand 5260 (±)-rolipram, (R,S)-rolipram
ROMe Immunopharmacology Ligand 6625 (R)-FTY720 methyl ether, (R)-FTY720-OMe
RORC2 inverse agonist 66 [PMID: 30130103] Immunopharmacology Ligand 10078 example 5 [WO2016046755A1]
rosiptor Immunopharmacology Ligand 9249 AQX-1125, AQX1125
rovazolac Immunopharmacology Ligand 9625 A-110, ALX-101, example 36 [WO2013130892]
RP-101075 Immunopharmacology Ligand 9889
RS-102895 PDB Ligand Immunopharmacology Ligand 779 abaucin, RS102895
RS-504393 Immunopharmacology Ligand 781 RS 504393, RS504393
rupatadine Approved drug Immunopharmacology Ligand 10103 Rinialer®, Rupafin®, UR-12592, UR12592
ruxolitinib Approved drug PDB Ligand Immunopharmacology Ligand 5688 (R)-ruxolitinib, INC424, INCB 18424, INCB018424, Jakafi®, Jakavi®
RV1729 Immunopharmacology Ligand 10162 RV-1729
RV6153 Immunopharmacology Ligand 10163 RV-6153
RWJ-56423 PDB Ligand Immunopharmacology Ligand 9333 (2S)-6
 
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S4-1 Immunopharmacology Ligand 12321
salbutamol Approved drug Immunopharmacology Ligand 558 albuterol, SCH-13949W, Ventolin®
salmeterol Approved drug Immunopharmacology Ligand 559 GR 33343X, Serevent®
Sanofi-14h Immunopharmacology Ligand 13067 compound 14h [PMID: 25589934]
SAR-20347 Immunopharmacology Ligand 9803
SB202190 PDB Ligand Immunopharmacology Ligand 4307 SB 202190, SB-202190
SB203580 Immunopharmacology Ligand 5269 PB 203580, RWJ 64809, SB-203580
SB 225002 Immunopharmacology Ligand 833 SB-225002, SB225002
SB290157 Immunopharmacology Ligand 3529 SB-290157
SB328437 Immunopharmacology Ligand 3530 SB 328437, SB-328437
SC-51089 Immunopharmacology Ligand 1923 SC 51089
Sch.336 Immunopharmacology Ligand 9799 analog 4j [PMID: 15664857], SCH-336, SCH336
SD-208 Immunopharmacology Ligand 8246 SCI-208, SD 208
S-26d [PMID: 37883692] Immunopharmacology Ligand 12979
seletalisib Immunopharmacology Ligand 9800 UCB 5857, UCB-5857, UCB5857
selinexor Approved drug Immunopharmacology Ligand 10036 compound 70 [WO2013019561A1], KPT-330, KPT330, Nexpovio®, Xpovio®
selnoflast Immunopharmacology Ligand 12173 Example 6 [WO2019008025A1], RG-6418, RG6418
selonsertib PDB Ligand Immunopharmacology Ligand 9040 GS-4997
S-EMCA PDB Ligand Immunopharmacology Ligand 7048 6α-ethyl-23(S)-methyl-cholic acid, INT-777, INT777
serlopitant Immunopharmacology Ligand 9280 compound 17 (Jiang et al. 2009), VPD-737
setanaxib Immunopharmacology Ligand 9932 GKT-137831, GKT-831, GKT137831, GKT831
setipiprant Immunopharmacology Ligand 10180 ACT-129968, ACT129968, compound 28 [PMID: 23721423]
setogepram Immunopharmacology Ligand 10043 3-pentylbenzeneacetic acid, fezagepras, PBI-4050, PBI4050
SGC-CBP30 PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 7529
SIAIS178 Immunopharmacology Ligand 10526 compound 19 [PMID: 31539241], SIAIS-178
siponimod Approved drug PDB Ligand Immunopharmacology Ligand 9289 BAF-312, BAF312, compound 32 [PMID: 24900670], Mayzent®
sirolimus Approved drug PDB Ligand Immunopharmacology Ligand 6031 AY-22989, Fyarro® (sirolimus albumin-bound particles), Rapamune®, rapamycin, WY-090217
SIRT1 activator 3 Immunopharmacology Ligand 9514 SA-3, SA3
SLM6071469 Immunopharmacology Ligand 10641 compound 10 [PMID: 31895563]
SNX0723 PDB Ligand Immunopharmacology Ligand 9260
sofnobrutinib Immunopharmacology Ligand 10094 compound 4b [PMID: 30216722]
solcitinib Immunopharmacology Ligand 9697 compound 1 [WO2010149771], GLPG-0778, GLPG0778, GSK2586184
sotrastaurin PDB Ligand Immunopharmacology Ligand 7946 AEB-071, AEB071
sotuletinib Immunopharmacology Ligand 8250 BLZ 945, BLZ-945, BLZ945
SP-4206 PDB Ligand Immunopharmacology Ligand 9037 compound 13 [PMID:12656598], SP4206
SP600125 PDB Ligand Immunopharmacology Ligand 5273 1,9-pyrazoloanthrone, JNK Inhibitor II, SP-600125
sparsentan Approved drug Immunopharmacology Ligand 8448 DARA-a (Dual Acting Receptor Antagonist of angiotension and endothelin receptors), BMS-346567, compound 7 [PMID 15634011], Filspari®, RE-021, retrophin
spebrutinib Immunopharmacology Ligand 7837 AVL 292, AVL-292, cc-292
sphingomyelin synthase 2 inhibitor 15w Immunopharmacology Ligand 10054 compound 15w [PMID: 30074791]
SPRi3 PDB Ligand Immunopharmacology Ligand 10130 example 23 [WO2011047156], SPR inhibitor 3
SR1001 Immunopharmacology Ligand 10143 SR-1001
SR144528 Immunopharmacology Ligand 751 SR 144528, SR-144528
SR1555 Immunopharmacology Ligand 10145 SR-1555
SR2211 PDB Ligand Immunopharmacology Ligand 10144 SR-2211
SR2640 Immunopharmacology Ligand 3329 SR 2640, SR-2640
SR8185 Immunopharmacology Ligand 9578 SR-8185
SRT1720 PDB Ligand Immunopharmacology Ligand 7703
SRT2104 Immunopharmacology Ligand 9515 compound 4 [Ng et al., 2013], GSK2245840, SRT-2104
SS-208 PDB Ligand Immunopharmacology Ligand 10490 compound 7b [PMID: 31414801], SS208
STING agonist 2 PDB Ligand Immunopharmacology Ligand 10127
STING agonist 3 Immunopharmacology Ligand 10128 compound 3 [PMID: 30405246], diABZI, diABZI STING agonist-1
(R)-STU104 Immunopharmacology Ligand 12006 (R)-4e [PMID: 35442672]
sulindac Approved drug Immunopharmacology Ligand 5425 Clinoril®
suprofen Approved drug Immunopharmacology Ligand 7298 Profenal®, R-25061
SX682 Immunopharmacology Ligand 10165
Syk inhibitor Immunopharmacology Ligand 6046 K00564a, spleen tyrosine kinase inhibitor
Syk inhibitor II Immunopharmacology Ligand 6047 K00592a
SZM679 Immunopharmacology Ligand 12311 SZM-679
 
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T0901317 PDB Ligand Immunopharmacology Ligand 2755 T 0901317, T-0901317
TAK-632 PDB Ligand Immunopharmacology Ligand 10387 compound 8B [PMID: 23906342], TAK632
TAK-715 PDB Ligand Immunopharmacology Ligand 9328 compound 8h [PMID: 16162000], TAK 715, TAK0715
TAK-779 Immunopharmacology Ligand 783 TAK779
TAK-981 Immunopharmacology Ligand 11305 Example 133 [WO2016004136A1], I-263a [WO2016004136A1], subasumstat (proposed INN), TAK981
TAK-828F PDB Ligand Immunopharmacology Ligand 9867 compound 10 [PMID: 29510038], TAK-828, TAK828F
Takinib PDB Ligand Immunopharmacology Ligand 9655
talabostat Immunopharmacology Ligand 9892 compound 1 [PMID: 18783201], PT-100, PT100, Val-boro-pro, Val-boroPro
talmapimod PDB Ligand Immunopharmacology Ligand 7817 SCIO 469 hydrochloride, SCIO-469
tamatinib PDB Ligand Immunopharmacology Ligand 5706 R 406, R-406, R406 free base
tanespimycin Immunopharmacology Ligand 7751 17-AAG, 17-allylamino-17-demethoxygeldanamycin, 17-N-allylamino-17-demethoxygeldanamycin, 17AAG, compound 4 [PMID:15978816]
tanzisertib Immunopharmacology Ligand 9836 CC-930, CC930, compound 1 [PMID: 22244937]
tapinarof Approved drug PDB Ligand Immunopharmacology Ligand 9686 benvitimod, GSK-2894512, GSK2894512, Vtama®, WB-1001, WBI 1001, WBI-1001
TAS05567 Immunopharmacology Ligand 9941
telotristat ethyl Approved drug Immunopharmacology Ligand 9490 LX-1606, LX1606, Xermelo®
tenalisib Immunopharmacology Ligand 9907 RP-6530, RP6530
teneligliptin Approved drug PDB Ligand Immunopharmacology Ligand 9906 compound 8g [PMID: 22959556], MP-513, MP513, Teneli
tepilamide fumarate Immunopharmacology Ligand 9770 XP 23829, XP-23829, XP23829
TEPP-46 Immunopharmacology Ligand 10555 compound 46 [PMID: 20451379], ML-265, ML265, TEPP46
terfenadine Approved drug Immunopharmacology Ligand 2608 RMI-9918, Seldane®, Triludan®
teriflunomide Approved drug PDB Ligand Immunopharmacology Ligand 6844 A77 1726, Aubagio®, flucyamide, HMR-1726
tetomilast Immunopharmacology Ligand 9877 compound 19f [PMID: 7830278], OPC-6535, OPC6535
TG11-77 Immunopharmacology Ligand 10603 compound 20o [PMID: 31904232]
TG6-129 Immunopharmacology Ligand 9283
TG8-260 Immunopharmacology Ligand 12520 compound 2f [PMID: 35187419], TG8260
TH5487 PDB Ligand Immunopharmacology Ligand 10184 TH-5487
thalidomide Approved drug Immunopharmacology Ligand 7327 K-17
tigemocoxib PDB Ligand Immunopharmacology Ligand 13505 29b-(S) [PMID: 20709553], SC-75416, SC75416
timapiprant Immunopharmacology Ligand 9277 OC000459, OC459
tiotropium Approved drug Immunopharmacology Ligand 367 BA-679-BR, Spiriva®
tirabrutinib Approved drug Immunopharmacology Ligand 9265 GS-4059, ONO-4059, ONO4059, Velexbru®
TK05 Immunopharmacology Ligand 9556
TM30089 Immunopharmacology Ligand 1905 CAY 10471, CAY-10471, CAY10471
tofacitinib Approved drug PDB Ligand Immunopharmacology Ligand 5677 CP-690,550, CP-690550, tasocitinib, Xeljanz®
tolebrutinib Immunopharmacology Ligand 10625 BTK'168, example 3 [WO2016196840A1], PRN-2246, PRN2246, SAR442168
tolmetin Approved drug PDB Ligand Immunopharmacology Ligand 7311 MCN-2559, McN-2559-21-98, Tolectin®
tomivosertib PDB Ligand Immunopharmacology Ligand 10167 compound 23 [PMID: 29526098], eFT-508, eFT508
toreforant Immunopharmacology Ligand 9276 JNJ-38518168
tradipitant Immunopharmacology Ligand 9278 LY-686017, LY686017, VLY-686
TRAM-34 Immunopharmacology Ligand 2336
tranilast Approved drug PDB Ligand Immunopharmacology Ligand 6326 MK-341, SB-252218
triamcinolone Approved drug Immunopharmacology Ligand 2870 fluoxiprednisolone, Kenalog®, Nasacort®
triamcinolone acetonide Approved drug PDB Ligand Immunopharmacology Ligand 2867 Zilretta®
trifarotene Approved drug PDB Ligand Immunopharmacology Ligand 9962 Aklief®, CD5789, compound 15b [PMID: 29706423]
trilaciclib Approved drug Immunopharmacology Ligand 9626 Cosela®, G1T28
tripelennamine Approved drug Immunopharmacology Ligand 7318 Pyribenzamine®
triple modulator 10 [PMID: 29878767] Immunopharmacology Ligand 10002
tryptanthrin 5i Immunopharmacology Ligand 10126 compound 5i [PMID: 24099220]
tubastatin A PDB Ligand Immunopharmacology Ligand 9702
TUG-1375 Immunopharmacology Ligand 10107 compound 31 [PMID: 30247908], TUG1375
TY-51469 Immunopharmacology Ligand 9779
TYD-68 Immunopharmacology Ligand 13823 TYK2 PROTAC 15t [PMID: 40116635]
TYK2 inhibitor 14l Immunopharmacology Ligand 11425
 
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U46619 PDB Ligand Immunopharmacology Ligand 1888 11α,9α-epoxymethano-PGH2, U 46619, U-46619
umbralisib Approved drug Immunopharmacology Ligand 8916 example A1 [US2014011819], RP-5264, RP5264, TGR-1202, TGR1202, Ukoniq®
umeclidinium Approved drug Immunopharmacology Ligand 7354 GSK573719A, Incruse Ellipta®
UNC4203 Immunopharmacology Ligand 10131 MERTK inhibitor 19 [PMID: 30347155], UNC4203A [US20150291606A1]
upadacitinib Approved drug Immunopharmacology Ligand 9246 ABT-494, Rinvoq®
uracil 20 Immunopharmacology Ligand 9901
usnoflast Immunopharmacology Ligand 12883 Example-6 [WO2020148619A1], ZY-IL1, ZYIL-1, ZYIL1
 
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vactosertib PDB Ligand Immunopharmacology Ligand 8107 EW-7197, EW7197, NOV-1301, TEW-7197
valategrast Immunopharmacology Ligand 11487 R-411, RO-0272441
valdecoxib Approved drug PDB Ligand Immunopharmacology Ligand 2894 Bextra®, SC-65872
vamorolone Approved drug Immunopharmacology Ligand 9247 Agamree®, VBP-15, VBP15
vanin-1 inhibitor [PMID: 33196323] Immunopharmacology Ligand 11718 example 1 [WO2016193844A1]
varespladib PDB Ligand Immunopharmacology Ligand 9657 compound 6m [PMID: 8978844], LY315920, S-5920, varespladib methyl (A-002), varespladib sodium (A-001)
VCE-004.3 Immunopharmacology Ligand 10030
vecabrutinib Immunopharmacology Ligand 10231 BIIB-062, BIIB062, SNS-062, SNS062
velsecorat PDB Ligand Immunopharmacology Ligand 9325 AZ13189620, AZD7594, compound 15m [PMID: 28937774]
vemurafenib Approved drug PDB Ligand Immunopharmacology Ligand 5893 PLX4032, RG7204, Zelboraf®
venetoclax Approved drug PDB Ligand Immunopharmacology Ligand 8318 ABT-199, GDC-0199, Venclexta®, Venclyxto®
vercirnon PDB Ligand Immunopharmacology Ligand 9046 CCX282-B, GSK'786, GSK1605786, GSK1605786A, Traficet-EN
verdiperstat PDB Ligand Immunopharmacology Ligand 10052 AZD-3241, AZD3241
verlukast Immunopharmacology Ligand 6193 MK-679, MK679
vidofludimus PDB Ligand Immunopharmacology Ligand 9860 4SC-101, IMU-838 (vidofludimus calcium), SC12267
vidupiprant Immunopharmacology Ligand 10169 AMG 853, AMG-853, AMG853, compound 2 [PMID: 24900313]
vilanterol Approved drug Immunopharmacology Ligand 7353 GW642444X
vimnerixin Immunopharmacology Ligand 12100 AZD-4721, AZD4721, compound 4 [WO2019055509A1], RIST4721
vipadenant PDB Ligand Immunopharmacology Ligand 5612 BIIB 014, BIIB014, V2006
vipoglanstat Immunopharmacology Ligand 12209 BI 1029539, BI-1029539, BI1029539, GS-248, GS248
vortioxetine Approved drug PDB Ligand Immunopharmacology Ligand 7351 Brintellix®, compound 5m [PMID: 21486038], Lu AA21004, Trintellix®
VRT-043198 PDB Ligand Immunopharmacology Ligand 9034
VX-702 Immunopharmacology Ligand 6059 I14-1965, VX 702, VX702
 
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1400W PDB Ligand Immunopharmacology Ligand 5102 W 1400
WH-4-023 Immunopharmacology Ligand 8068
WJYK50 Immunopharmacology Ligand 10639 compound 1c [PMID: 29649738]
WN1703 Immunopharmacology Ligand 13463 compound 16c [PMID: 28918097], WN-1703, XOR inhibitor 16c
WXFL10203614 Immunopharmacology Ligand 12621 WX614, WXFL-10203614
 
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YM90709 Immunopharmacology Ligand 5090 YM 90709, YM-90709
 
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zabedosertib Immunopharmacology Ligand 11415 BAY-1834845, BAY1834845
zafirlukast Approved drug PDB Ligand Immunopharmacology Ligand 3322 Accolate®, ICI-204219
zaloglanstat Immunopharmacology Ligand 11406
zanubrutinib Approved drug Immunopharmacology Ligand 9861 BGB-3111, BGB3111, Brukinsa®, compound 27b [US9447106]
zasocitinib PDB Ligand Immunopharmacology Ligand 12155 compound I-908 [US20190256519A1], NDI-034858, NDI034858, TAK-279, TAK279
zaurategrast Immunopharmacology Ligand 11488 CDP-323, CDP323
zelebrudomide Immunopharmacology Ligand 13490 compound 28 [PMID: 38300987], NX-2127, NX2127
zelnecirnon Immunopharmacology Ligand 12893 example 37 [WO2019147862A1], RPT-193, RPT193
zemprocitinib Immunopharmacology Ligand 13221 compound 1 [US20220009927]
zenuzolac Immunopharmacology Ligand 11682 (S,R)-3-Phenyl-4,5-dihydro-5-isoxazole acetic acid, GIT-027, GIT-27, GIT27, GLS-1027, GLS1027, rac-[(5R)-3-phenyl-4,5-dihydro-1,2-oxazol-5-yl]acetic acid, VGX-1027, VGX1027
zetomipzomib Immunopharmacology Ligand 10409 compound 12 [PMID: 30380863], KZR-616, KZR616
zileuton Approved drug Immunopharmacology Ligand 5297 A-64077, ZYFLO®
zimlovisertib PDB Ligand Immunopharmacology Ligand 9667 compound 40 [PMID: 28498658], PF-06650833, PF06650833
(R)-ZINC-3573 PDB Ligand Immunopharmacology Ligand 9566 ZINC-72453573
ziritaxestat PDB Ligand Immunopharmacology Ligand 9561 compound 11 [PMID: 28414242], GLPG-1690, GLPG1690
ZK 756326 PDB Ligand Immunopharmacology Ligand 813 ZK-756326, ZK756326
ZLN005 Immunopharmacology Ligand 13255 ZLN 005, ZLN-005
zomiradomide Immunopharmacology Ligand 11904 compound A [WO2022027058A1]