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ChEMBL ligand: CHEMBL1201610 (Cortrophin, Corticotropin, Adrenomone, Cortigel, ACTH, Adrenocorticotropin, H.P. Acthar Gel, Acthar, Acthar Gel, Repository Corticotropin, Purified Cortrophin Gel, Corticotropin, Repository, Adrenocorticotropic Hormone) |
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CHEMBL1201610_lig_chart_1
MC1 receptor
Human
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2
CHEMBL1201610_lig_chart_2
MC3 receptor
Human
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3
CHEMBL1201610_lig_chart_3
MC4 receptor
Human
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4
CHEMBL1201610_lig_chart_4
MC5 receptor
Human
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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MC1 receptor in Human [GtoPdb: 282] [UniProtKB: Q01726] | ||||||||
GtoPdb | - | - | 8.6 | pKi | 2.5 | nM | Ki | Eur J Pharmacol (1995) 288: 311-317 [PMID:7774675] |
MC3 receptor in Human [GtoPdb: 284] [UniProtKB: P41968] | ||||||||
GtoPdb | - | - | 7.06 | pKi | 86.9 | nM | Ki | Eur J Pharmacol (1995) 288: 311-317 [PMID:7774675] |
MC4 receptor in Human [GtoPdb: 285] [UniProtKB: P32245] | ||||||||
GtoPdb | - | - | 6.16 | pKi | 693 | nM | Ki | Pharmacol. Toxicol. (1996) 79: 161-5 [PMID:8884876] |
MC5 receptor in Human [GtoPdb: 286] [UniProtKB: P33032] | ||||||||
GtoPdb | - | - | 5 | pKi | >10000 | nM | Ki | Eur J Pharmacol (1995) 288: 311-317 [PMID:7774675] |
ChEMBL data shown on this page come from version 27:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]