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Synonyms: Betaferon® | Betaseron® | Extavia® | IFNb1b
IFN-β1b (recombinant human) is an approved drug (FDA (1993), EMA (1995))
Compound class:
Peptide
Comment: Compared to the sequence of endogenous IFN-β, IFN-β1b has a Ser to Cys substitution at position 17, but does not retain the glycosylation site at Asn80. It also lacks the initiating Met. This recombinant peptide is produced in E.coli.
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Classification ![]() |
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| Compound class | Peptide |
| Approved drug? | Yes. EU EMA (1995) | US FDA (1993) |
International Nonproprietary Names ![]() |
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| INN number | INN |
| 5380 | interferon beta |
Synonyms ![]() |
| Betaferon® | Betaseron® | Extavia® | IFNb1b |
Database Links ![]() |
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| Specialist databases | |
| IMGT/mAb-DB | 641 |
| Other databases | |
| DrugBank Ligand | DB00068 |
| GtoPdb PubChem SID | 252166552 |
| Search PubMed clinical trials | interferon beta |
| Search PubMed titles | interferon beta |
| Search PubMed titles/abstracts | interferon beta |
| Wikipedia | Interferon_beta_1b |