pomalidomide   Click here for help

GtoPdb Ligand ID: 7348

Synonyms: CC-4047 | IMID-3 | Imnovid® | Pomalyst®
Approved drug Immunopharmacology Ligand
pomalidomide is an approved drug (FDA and EMA (2013))
Compound class: Synthetic organic
Comment: Pomalidomide is an analogue of thalidomide with similar immunomodulatory antineoplastic activity.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 109.57
Molecular weight 273.07
XLogP -0.56
No. Lipinski's rules broken 0
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Canonical SMILES O=C1CCC(C(=O)N1)N1C(=O)c2c(C1=O)c(N)ccc2
Isomeric SMILES O=C1CCC(C(=O)N1)N1C(=O)c2c(C1=O)c(N)ccc2
InChI InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)
Classification Click here for help
Compound class Synthetic organic
Ligand families/groups PROTACs, molecular glues and other degraders
Approved drug? Yes (FDA and EMA (2013))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
8873 pomalidomide
Synonyms Click here for help
CC-4047 | IMID-3 | Imnovid® | Pomalyst®
Database Links Click here for help
Specialist databases
Reactome Drug Reactome logo R-ALL-9681202
Reactome Reaction Reactome logo R-HSA-9681169
Other databases
CAS Registry No. 19171-19-8 (source: Scifinder)
ChEMBL Ligand CHEMBL43452
DrugBank Ligand DB08910
DrugCentral Ligand 4746
GtoPdb PubChem SID 178103920
PubChem CID 134780
Search Google for chemical match using the InChIKey UVSMNLNDYGZFPF-UHFFFAOYSA-N
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UniChem Compound Search for chemical match using the InChIKey UVSMNLNDYGZFPF-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey UVSMNLNDYGZFPF-UHFFFAOYSA-N
Wikipedia Pomalidomide

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Pomalidomide (links to external site)
Cat. No. 6302