ChEMBL ligand: CHEMBL1263 (Beglan, Cryogenine, GR 33343 X, GR-33343-X, GR-33343X, Neovent, NSC-272693, Salmaterol, Salmeterol, Serevent, SN408D, Soltel, Vertine)
β1-adrenoceptor/Beta-1 adrenergic receptor in Human [ChEMBL: CHEMBL213] [GtoPdb: 28] [UniProtKB: P08588] β1-adrenoceptor/Beta-1 adrenergic receptor in Mouse [ChEMBL: CHEMBL3440] [GtoPdb: 28] [UniProtKB: P34971] Beta-1 adrenergic receptor in Guinea pig [ChEMBL: CHEMBL5471] [UniProtKB: B0FL73] There should be some charts here, you may need to enable JavaScript!
β2-adrenoceptor/Beta-2 adrenergic receptor in Human [ChEMBL: CHEMBL210] [GtoPdb: 29] [UniProtKB: P07550] Beta-2 adrenergic receptor in Guinea pig [ChEMBL: CHEMBL5414] [UniProtKB: Q8K4Z4] There should be some charts here, you may need to enable JavaScript!
β3-adrenoceptor/Beta-3 adrenergic receptor in Human [ChEMBL: CHEMBL246] [GtoPdb: 30] [UniProtKB: P13945] There should be some charts here, you may need to enable JavaScript!
D2 receptor/Dopamine D2 receptor in Human [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416] There should be some charts here, you may need to enable JavaScript!
D3 receptor/Dopamine D3 receptor in Human [ChEMBL: CHEMBL234] [GtoPdb: 216] [UniProtKB: P35462] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
β1-adrenoceptor/Beta-1 adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL213] [GtoPdb: 28] [UniProtKB: P08588]
ChEMBL	Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay	B	5.6	pKi	2511.89	nM	Ki	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Displacement of [125I]-CYP from human beta1-adrenergic receptor expressed in COS-7 cells by gamma counting	B	5.64	pKi	2300	nM	Ki	Bioorg Med Chem (2010) 18: 728-736 [PMID:20036561]
ChEMBL	Displacement of [3H]CGP12177 from human beta-1 adrenoceptor	B	6.1	pKi	801	nM	Ki	Bioorg Med Chem Lett (2010) 20: 5302-5307 [PMID:20655218]
ChEMBL	Displacement of [125I]iodo-(+/-)-cyanopindolol from human adrenergic beta1 receptor expressed in CHO cells after 3 hrs by radio-ligand binding assay	B	6.11	pKi	784	nM	Ki	Bioorg Med Chem Lett (2014) 24: 4341-4347 [PMID:25065493]
ChEMBL	Binding affinity to adrenergic beta1 receptor	B	6.3	pIC50	501.19	nM	IC50	Bioorg Med Chem Lett (2011) 21: 4612-4616 [PMID:21723724]
ChEMBL	Binding affinity to beta1 adrenoceptor	B	6.3	pIC50	501.19	nM	IC50	Bioorg Med Chem Lett (2012) 22: 689-695 [PMID:22079756]
ChEMBL	Agonist activity at beta1-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring Rluc2-117-GalphaS/GFP10-Ggamma/Gbeta1 assessed as activation of GalphaS incubated for 5 mins in presence of coelenterazine 400a by BRET assay	B	5.3	pEC50	5011.87	nM	EC50	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
ChEMBL	Agonist activity at human beta1 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay	F	5.91	pEC50	1230.27	nM	EC50	Bioorg Med Chem (2019) 27: 2306-2314 [PMID:30392952]
ChEMBL	Agonist activity at adrenergic beta1 receptor	F	6.1	pEC50	794.33	nM	EC50	Bioorg Med Chem Lett (2011) 21: 4612-4616 [PMID:21723724]
ChEMBL	Agonist activity at human adrenergic beta1 receptor expressed in CHO cells assessed as cAMP accumulation	F	6.1	pEC50	794.33	nM	EC50	Bioorg Med Chem (2011) 19: 4192-4201 [PMID:21696967]
ChEMBL	Agonist activity at human beta1 receptor expressed in CHO cells assessed as cAMP accumulation	F	6.1	pEC50	794.33	nM	EC50	Bioorg Med Chem (2011) 19: 6026-6032 [PMID:21925889]
ChEMBL	Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation by beta-galactosidase based whole cell assay	F	6.1	pEC50	794.33	nM	EC50	J Med Chem (2009) 52: 2280-2288 [PMID:19317397]
ChEMBL	Agonist activity at human beta1 adrenoceptor transfected in CHO cells assessed as cyclic AMP accumulation after 45 mins by fluorescence polarization assay	B	6.1	pEC50	794.33	nM	EC50	J Med Chem (2014) 57: 159-170 [PMID:24359185]
ChEMBL	Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation after 30 to 45 mins	F	6.1	pEC50	794.33	nM	EC50	J Med Chem (2010) 53: 4522-4530 [PMID:20462258]
ChEMBL	Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulation	F	6.43	pEC50	371.54	nM	EC50	Eur J Med Chem (2021) 224: 113697-113697 [PMID:34273662]
ChEMBL	Agonist activity at human beta1 adrenergic receptor expressed in cells by cAMP accumulation assay	F	6.6	pEC50	251.19	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2871-2876 [PMID:24835980]
ChEMBL	Agonist activity at human recombinant beta1 receptor assessed as cAMP accumulation by radioimmunoassay and cell based assay	F	6.6	pEC50	251.19	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Agonist activity at recombinant human beta1-adrenoceptor expressed in whole cells assessed as cAMP accumulation by homogeneous radioimmunoassay	F	6.6	pEC50	251.19	nM	EC50	Bioorg Med Chem Lett (2012) 22: 1213-1218 [PMID:22178551]
ChEMBL	Agonist activity at beta1-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring GFP/Rluc2-tagged beta-arrestin2 assessed as increase in beta-arrestin2 recruitment incubated for 5 mins in presence of GRK5 and coelenterazine 400a by BRET assay	B	6.7	pEC50	199.53	nM	EC50	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
ChEMBL	Agonist activity at human beta1 adrenoceptor expressed in CHO cells assessed as increase in intracellular cAMP level incubated for 1 hr by alphascreen technology	F	7.17	pEC50	67	nM	EC50	J Med Chem (2020) 63: 15218-15242 [PMID:33213146]
β1-adrenoceptor/Beta-1 adrenergic receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3440] [GtoPdb: 28] [UniProtKB: P34971]
ChEMBL	Displacement of [3H]-CGP-12177 from murine beta1-adrenergic receptor expressed in HEK293T cells after 60 mins by radioligand competition binding assay	B	6.26	pKi	550	nM	Ki	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
Beta-1 adrenergic receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5471] [UniProtKB: B0FL73]
ChEMBL	Agonist activity at beta-1 adrenergic receptor in guinea pig trachea assessed as inhibition of electrical stimulation-induced muscle contraction	F	8.3	pEC50	5.01	nM	EC50	J Med Chem (2009) 52: 2280-2288 [PMID:19317397]
β2-adrenoceptor/Beta-2 adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL210] [GtoPdb: 29] [UniProtKB: P07550]
ChEMBL	Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes assessed as intrinsic Kd by liquid scintillation counting	B	5.96	pKd	1100	nM	Kd	J Med Chem (2016) 59: 5780-5789 [PMID:27239696]
ChEMBL	Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation counting	B	9.52	pKd	0.3	nM	Kd	J Med Chem (2016) 59: 5780-5789 [PMID:27239696]
ChEMBL	Displacement of [125I]-CYP from human beta2-adrenergic receptor Y308A mutant expressed in COS-7 cells by gamma counting	B	6.74	pKi	184	nM	Ki	Bioorg Med Chem (2010) 18: 728-736 [PMID:20036561]
ChEMBL	Displacement of [125I]iodo-(+/-)-cyanopindolol from human adrenergic beta2 receptor expressed in CHO cells after 3 hrs by radio-ligand binding assay	B	8.49	pKi	3.2	nM	Ki	Bioorg Med Chem Lett (2014) 24: 4341-4347 [PMID:25065493]
ChEMBL	Displacement of [3H]CGP12177 from human beta2 adrenoceptor	B	8.49	pKi	3.2	nM	Ki	Bioorg Med Chem Lett (2010) 20: 5302-5307 [PMID:20655218]
ChEMBL	Displacement of [3H]dihydroalprenolol from human beta2 adrenergic receptor expressing cell membrane by competition binding assay	B	8.6	pKi	2.51	nM	Ki	Bioorg Med Chem Lett (2014) 24: 2871-2876 [PMID:24835980]
ChEMBL	Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay	B	8.6	pKi	2.51	nM	Ki	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Displacement of [3H]-dihydroalprenolol from human beta2-adrenoceptor expressed in HEK cells after 4 hrs	B	8.62	pKi	2.4	nM	Ki	Bioorg Med Chem Lett (2011) 21: 1354-1358 [PMID:21310610]
ChEMBL	Displacement of [125I]-CYP from human beta2-adrenergic receptor expressed in COS-7 cells by gamma counting	B	8.82	pKi	1.5	nM	Ki	Bioorg Med Chem (2010) 18: 728-736 [PMID:20036561]
ChEMBL	Binding affinity for human beta-2 adrenergic receptor	B	9	pKi	1	nM	Ki	Bioorg Med Chem Lett (2004) 14: 4705-4710 [PMID:15324892]
GtoPdb	-	-	9.3	pKi	-	-	Kd	Br J Pharmacol (2010) 160: 1048-61 [PMID:20590599]; Br J Pharmacol (2022) 179: 4692-4708 [PMID:35732075]; Mol Pharmacol (2015) 87: 103-20 [PMID:25324048]
ChEMBL	Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assay	B	9.41	pKi	0.39	nM	Ki	J Med Chem (2010) 53: 3675-3684 [PMID:20402514]
ChEMBL	Displacement of [3H]-CGP-12177 from human beta2-adrenergic receptor expressed in CHO cells after 60 mins by radioligand competition binding assay	B	9.6	pKi	0.25	nM	Ki	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
ChEMBL	Displacement of [3H]CGP12177 from human beta2 receptor expressed in CHO cells	B	9.74	pKi	0.18	nM	Ki	Bioorg Med Chem (2016) 24: 2641-2653 [PMID:27132867]
ChEMBL	Displacement of [3H]dihydroalprenolol from beta2-adrenoceptor after 90 mins by liquid scintillation counting	B	8.3	pIC50	5.01	nM	IC50	Bioorg Med Chem Lett (2012) 22: 1213-1218 [PMID:22178551]
ChEMBL	Agonist activity at human beta2 adrenoceptor expressed in H292 cells assessed as increase in cAMP accumulation after 60 mins by spectrophotometry	F	9.1	pEC50	0.79	nM	EC50	Bioorg Med Chem Lett (2012) 22: 689-695 [PMID:22079756]
ChEMBL	Agonist activity at beta2-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring Rluc2-117-GalphaS/GFP10-Ggamma/Gbeta1 assessed as activation of GalphaS incubated for 5 mins in presence of coelenterazine 400a by BRET assay	B	9.1	pEC50	0.79	nM	EC50	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
ChEMBL	Agonist activity at human adrenergic beta2 receptor expressed in H292 cells assessed as intracellular cAMP accumulation after 1 hr	F	9.1	pEC50	0.79	nM	EC50	Bioorg Med Chem Lett (2011) 21: 4027-4031 [PMID:21652207]
ChEMBL	Agonist activity at human adrenergic beta2 receptor expressed in H292 cells assessed as stimulation of cAMP accumulation after 60 mins	F	9.1	pEC50	0.79	nM	EC50	Bioorg Med Chem Lett (2011) 21: 4612-4616 [PMID:21723724]
ChEMBL	Agonist activity at human beta2 adrenoceptor expressed in CHO cells assessed as increase in intracellular cAMP level incubated for 1 hr by alphascreen technology	F	9.15	pEC50	0.71	nM	EC50	J Med Chem (2020) 63: 15218-15242 [PMID:33213146]
ChEMBL	Agonist activity at human beta2 receptor in BEAS-2B cells assessed as cAMP accumulation by radioimmunoassay	F	9.3	pEC50	0.5	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Agonist activity at beta2-adrenoceptor endogenously expressed in human BEAS-2B cells assessed as cAMP accumulation by homogeneous radioimmunoassay	F	9.3	pEC50	0.5	nM	EC50	Bioorg Med Chem Lett (2012) 22: 1213-1218 [PMID:22178551]
ChEMBL	Agonist activity at human beta2 adrenergic receptor in human BEAS-2B cells by cAMP accumulation assay	F	9.3	pEC50	0.5	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2871-2876 [PMID:24835980]
ChEMBL	Agonist activity at human beta2-adrenoceptor expressed in HEK cells assessed as increase of cAMP level after 10 mins by radioimmunoassay	F	9.48	pEC50	0.33	nM	EC50	Bioorg Med Chem Lett (2011) 21: 1354-1358 [PMID:21310610]
ChEMBL	Agonist activity at human beta2 adrenergic receptor assessed as increase in cAMP level by whole cell assay	F	9.49	pEC50	0.32	nM	EC50	J Med Chem (2010) 53: 3675-3684 [PMID:20402514]
ChEMBL	Agonist activity at human beta2 adrenergic receptor expressed in cells by cAMP accumulation assay	F	9.5	pEC50	0.32	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2871-2876 [PMID:24835980]
ChEMBL	Agonist activity at recombinant human beta2-adrenoceptor expressed in whole cells assessed as cAMP accumulation by homogeneous radioimmunoassay	F	9.5	pEC50	0.32	nM	EC50	Bioorg Med Chem Lett (2012) 22: 1213-1218 [PMID:22178551]
ChEMBL	Agonist activity at human recombinant beta2 receptor assessed as cAMP accumulation by radioimmunoassay and cell based assay	F	9.5	pEC50	0.32	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Agonist activity at human adrenergic beta2 receptor expressed in CHO cells assessed as cAMP accumulation	F	9.6	pEC50	0.25	nM	EC50	Bioorg Med Chem (2011) 19: 4192-4201 [PMID:21696967]
ChEMBL	Agonist activity at human beta2 adrenoceptor transfected in CHO cells assessed as cyclic AMP accumulation after 45 mins by fluorescence polarization assay	F	9.6	pEC50	0.25	nM	EC50	J Med Chem (2014) 57: 159-170 [PMID:24359185]
ChEMBL	Agonist activity at human cloned beta2 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation by beta-galactosidase based whole cell assay	F	9.6	pEC50	0.25	nM	EC50	J Med Chem (2009) 52: 2280-2288 [PMID:19317397]
ChEMBL	Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation after 30 to 45 mins	F	9.6	pEC50	0.25	nM	EC50	J Med Chem (2010) 53: 4522-4530 [PMID:20462258]
ChEMBL	Agonist activity at human beta2 receptor expressed in CHO cells assessed as cAMP accumulation	F	9.6	pEC50	0.25	nM	EC50	Bioorg Med Chem (2011) 19: 6026-6032 [PMID:21925889]
ChEMBL	Agonist activity at human beta2 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulation	F	9.87	pEC50	0.13	nM	EC50	Eur J Med Chem (2021) 224: 113697-113697 [PMID:34273662]
ChEMBL	Agonist activity at beta2-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring GFP/Rluc2-tagged beta-arrestin2 assessed as increase in beta-arrestin2 recruitment incubated for 5 mins in presence of GSK2 and coelenterazine 400a by BRET assay	B	9.9	pEC50	0.13	nM	EC50	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
GtoPdb	-	-	9.9	pEC50	-	-	-	Br J Pharmacol (2010) 160: 1048-61 [PMID:20590599]; J Pharmacol Exp Ther (2006) 317: 762-70 [PMID:16434564]
ChEMBL	Agonist activity at beta2-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring GFP/Rluc2-tagged beta-arrestin2 assessed as increase in beta-arrestin2 recruitment incubated for 5 mins in presence of GSK5 and coelenterazine 400a by BRET assay	B	10.1	pEC50	0.08	nM	EC50	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
ChEMBL	Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay	F	10.11	pEC50	0.08	nM	EC50	Bioorg Med Chem (2019) 27: 2306-2314 [PMID:30392952]
ChEMBL	Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as elevation in cAMP level after 1 hr by flashplate method	F	10.15	pEC50	0.07	nM	EC50	J Med Chem (2010) 53: 6640-6652 [PMID:20804199]
ChEMBL	Agonist activity at human recombinant beta-2 adrenoceptor expressed in CHO cells assessed as elevation of cAMP	F	10.15	pEC50	0.07	nM	EC50	Bioorg Med Chem Lett (2007) 17: 4012-4015 [PMID:17498952]
ChEMBL	Agonist activity at human recombinant adrenergic beta-2 receptor expressed in CHO cells assessed as elevation in cAMP levels	F	10.15	pEC50	0.07	nM	EC50	Bioorg Med Chem Lett (2007) 17: 6188-6191 [PMID:17897826]
ChEMBL	Agonist activity at human beta2 adrenoreceptor overexpressed in human HEK293 cells assessed as cAMP accumulation incubated for 60 mins by HTRF assay	F	10.35	pEC50	0.04	nM	EC50	Bioorg Med Chem (2020) 28: 115178-115178 [PMID:31753798]
Beta-2 adrenergic receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5414] [UniProtKB: Q8K4Z4]
ChEMBL	Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response after 30 mins	F	8.46	pIC50	3.5	nM	IC50	J Med Chem (2010) 53: 3675-3684 [PMID:20402514]
ChEMBL	Agonist activity at adrenergic beta2 receptor in electrically-stimulated Dunkin-Hartley guinea pig tracheal strip assessed as inhibition of contraction	B	8.46	pIC50	3.5	nM	IC50	Bioorg Med Chem Lett (2014) 24: 4341-4347 [PMID:25065493]
ChEMBL	Agonist activity at beta2 receptor in guinea pig trachea assessed as slow onset of inhibition of electrically stimulated contraction	B	7.5	pEC50	31.62	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Agonist activity at adrenergic beta2 receptor in guinea pig trachea assessed as inhibition of electrically-stimulated contraction	F	8.3	pEC50	5.01	nM	EC50	Bioorg Med Chem (2011) 19: 4192-4201 [PMID:21696967]
ChEMBL	Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response	F	8.3	pEC50	5.01	nM	EC50	Bioorg Med Chem (2011) 19: 6026-6032 [PMID:21925889]
ChEMBL	Agonist activity at beta2 adrenoceptor in guinea pig trachea assessed as inhibition of histamine-induced contraction	B	8.57	pEC50	2.7	nM	EC50	Bioorg Med Chem Lett (2015) 25: 5121-5126 [PMID:26471092]
β3-adrenoceptor/Beta-3 adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL246] [GtoPdb: 30] [UniProtKB: P13945]
ChEMBL	Agonist activity at human cloned beta3 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation by beta-galactosidase based whole cell assay	F	5.9	pEC50	1258.93	nM	EC50	J Med Chem (2009) 52: 2280-2288 [PMID:19317397]
ChEMBL	Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation after 30 to 45 mins	F	5.9	pEC50	1258.93	nM	EC50	J Med Chem (2010) 53: 4522-4530 [PMID:20462258]
ChEMBL	Agonist activity at human adrenergic beta3 receptor expressed in CHO cells assessed as cAMP accumulation	F	5.9	pEC50	1258.93	nM	EC50	Bioorg Med Chem (2011) 19: 4192-4201 [PMID:21696967]
ChEMBL	Agonist activity at human beta3 receptor expressed in CHO cells assessed as cAMP accumulation	F	5.9	pEC50	1258.93	nM	EC50	Bioorg Med Chem (2011) 19: 6026-6032 [PMID:21925889]
ChEMBL	Agonist activity at human beta3 adrenoceptor transfected in CHO cells assessed as cyclic AMP accumulation after 45 mins by fluorescence polarization assay	B	5.9	pEC50	1258.93	nM	EC50	J Med Chem (2014) 57: 159-170 [PMID:24359185]
ChEMBL	Agonist activity at human recombinant beta3 receptor assessed as cAMP accumulation by radioimmunoassay and cell based assay	F	6	pEC50	1000	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Agonist activity at human beta3 adrenergic receptor expressed in cells by cAMP accumulation assay	F	6	pEC50	1000	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2871-2876 [PMID:24835980]
D2 receptor/Dopamine D2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416]
ChEMBL	Displacement of [3H]spiperone from human D2S receptor expressed in CHO cells	B	4.49	pKi	32000	nM	Ki	Bioorg Med Chem (2016) 24: 2641-2653 [PMID:27132867]
D3 receptor/Dopamine D3 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL234] [GtoPdb: 216] [UniProtKB: P35462]
ChEMBL	Displacement of [125I]7-HO-PIPAT from human D3R expressed in HEK cells	B	5.98	pKi	1049	nM	Ki	Bioorg Med Chem Lett (2014) 24: 4341-4347 [PMID:25065493]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]