ChEMBL ligand: CHEMBL1263 (Beglan, Cryogenine, GR 33343 X, GR-33343X, GR-33343-X, Neovent, NSC-272693, Salmaterol, Salmeterol, Serevent, SN408D, Soltel, Vertine)
β1-adrenoceptor/Beta-1 adrenergic receptor in Human [ChEMBL: CHEMBL213] [GtoPdb: 28] [UniProtKB: P08588] β1-adrenoceptor/Beta-1 adrenergic receptor in Mouse [ChEMBL: CHEMBL3440] [GtoPdb: 28] [UniProtKB: P34971] Beta-1 adrenergic receptor in Guinea pig [ChEMBL: CHEMBL5471] [UniProtKB: B0FL73] There should be some charts here, you may need to enable JavaScript!
β2-adrenoceptor/Beta-2 adrenergic receptor in Human [ChEMBL: CHEMBL210] [GtoPdb: 29] [UniProtKB: P07550] Beta-2 adrenergic receptor in Guinea pig [ChEMBL: CHEMBL5414] [UniProtKB: Q8K4Z4] There should be some charts here, you may need to enable JavaScript!
β3-adrenoceptor/Beta-3 adrenergic receptor in Human [ChEMBL: CHEMBL246] [GtoPdb: 30] [UniProtKB: P13945] There should be some charts here, you may need to enable JavaScript!
D2 receptor/Dopamine D2 receptor in Human [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416] There should be some charts here, you may need to enable JavaScript!
D3 receptor/Dopamine D3 receptor in Human [ChEMBL: CHEMBL234] [GtoPdb: 216] [UniProtKB: P35462] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
β1-adrenoceptor/Beta-1 adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL213] [GtoPdb: 28] [UniProtKB: P08588]
ChEMBL	Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay	B	5.6	pKi	2511.89	nM	Ki	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Displacement of [125I]-CYP from human beta1-adrenergic receptor expressed in COS-7 cells by gamma counting	B	5.64	pKi	2300	nM	Ki	Bioorg Med Chem (2010) 18: 728-736 [PMID:20036561]
ChEMBL	Displacement of [3H]CGP12177 from human beta-1 adrenoceptor	B	6.1	pKi	801	nM	Ki	Bioorg Med Chem Lett (2010) 20: 5302-5307 [PMID:20655218]
ChEMBL	Displacement of [125I]iodo-(+/-)-cyanopindolol from human adrenergic beta1 receptor expressed in CHO cells after 3 hrs by radio-ligand binding assay	B	6.11	pKi	784	nM	Ki	Bioorg Med Chem Lett (2014) 24: 4341-4347 [PMID:25065493]
ChEMBL	Binding affinity to adrenergic beta1 receptor	B	6.3	pIC50	501.19	nM	IC50	Bioorg Med Chem Lett (2011) 21: 4612-4616 [PMID:21723724]
ChEMBL	Binding affinity to beta1 adrenoceptor	B	6.3	pIC50	501.19	nM	IC50	Bioorg Med Chem Lett (2012) 22: 689-695 [PMID:22079756]
ChEMBL	Agonist activity at beta1-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring Rluc2-117-GalphaS/GFP10-Ggamma/Gbeta1 assessed as activation of GalphaS incubated for 5 mins in presence of coelenterazine 400a by BRET assay	B	5.3	pEC50	5011.87	nM	EC50	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
ChEMBL	Agonist activity at human beta1 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay	F	5.91	pEC50	1230.27	nM	EC50	Bioorg Med Chem (2019) 27: 2306-2314 [PMID:30392952]
ChEMBL	Agonist activity at adrenergic beta1 receptor	F	6.1	pEC50	794.33	nM	EC50	Bioorg Med Chem Lett (2011) 21: 4612-4616 [PMID:21723724]
ChEMBL	Agonist activity at human adrenergic beta1 receptor expressed in CHO cells assessed as cAMP accumulation	F	6.1	pEC50	794.33	nM	EC50	Bioorg Med Chem (2011) 19: 4192-4201 [PMID:21696967]
ChEMBL	Agonist activity at human beta1 receptor expressed in CHO cells assessed as cAMP accumulation	F	6.1	pEC50	794.33	nM	EC50	Bioorg Med Chem (2011) 19: 6026-6032 [PMID:21925889]
ChEMBL	Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation by beta-galactosidase based whole cell assay	F	6.1	pEC50	794.33	nM	EC50	J Med Chem (2009) 52: 2280-2288 [PMID:19317397]
ChEMBL	Agonist activity at human beta1 adrenoceptor transfected in CHO cells assessed as cyclic AMP accumulation after 45 mins by fluorescence polarization assay	B	6.1	pEC50	794.33	nM	EC50	J Med Chem (2014) 57: 159-170 [PMID:24359185]
ChEMBL	Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation after 30 to 45 mins	F	6.1	pEC50	794.33	nM	EC50	J Med Chem (2010) 53: 4522-4530 [PMID:20462258]
ChEMBL	Agonist activity at human beta1 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulation	F	6.43	pEC50	371.54	nM	EC50	Eur J Med Chem (2021) 224: 113697-113697 [PMID:34273662]
ChEMBL	Agonist activity at human beta1 adrenergic receptor expressed in cells by cAMP accumulation assay	F	6.6	pEC50	251.19	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2871-2876 [PMID:24835980]
ChEMBL	Agonist activity at human recombinant beta1 receptor assessed as cAMP accumulation by radioimmunoassay and cell based assay	F	6.6	pEC50	251.19	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Agonist activity at recombinant human beta1-adrenoceptor expressed in whole cells assessed as cAMP accumulation by homogeneous radioimmunoassay	F	6.6	pEC50	251.19	nM	EC50	Bioorg Med Chem Lett (2012) 22: 1213-1218 [PMID:22178551]
ChEMBL	Agonist activity at beta1-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring GFP/Rluc2-tagged beta-arrestin2 assessed as increase in beta-arrestin2 recruitment incubated for 5 mins in presence of GRK5 and coelenterazine 400a by BRET assay	B	6.7	pEC50	199.53	nM	EC50	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
ChEMBL	Agonist activity at human beta1 adrenoceptor expressed in CHO cells assessed as increase in intracellular cAMP level incubated for 1 hr by alphascreen technology	F	7.17	pEC50	67	nM	EC50	J Med Chem (2020) 63: 15218-15242 [PMID:33213146]
β1-adrenoceptor/Beta-1 adrenergic receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3440] [GtoPdb: 28] [UniProtKB: P34971]
ChEMBL	Displacement of [3H]-CGP-12177 from murine beta1-adrenergic receptor expressed in HEK293T cells after 60 mins by radioligand competition binding assay	B	6.26	pKi	550	nM	Ki	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
Beta-1 adrenergic receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5471] [UniProtKB: B0FL73]
ChEMBL	Agonist activity at beta-1 adrenergic receptor in guinea pig trachea assessed as inhibition of electrical stimulation-induced muscle contraction	F	8.3	pEC50	5.01	nM	EC50	J Med Chem (2009) 52: 2280-2288 [PMID:19317397]
β2-adrenoceptor/Beta-2 adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL210] [GtoPdb: 29] [UniProtKB: P07550]
ChEMBL	Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes assessed as intrinsic Kd by liquid scintillation counting	B	5.96	pKd	1100	nM	Kd	J Med Chem (2016) 59: 5780-5789 [PMID:27239696]
ChEMBL	Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation counting	B	9.52	pKd	0.3	nM	Kd	J Med Chem (2016) 59: 5780-5789 [PMID:27239696]
ChEMBL	Displacement of [125I]-CYP from human beta2-adrenergic receptor Y308A mutant expressed in COS-7 cells by gamma counting	B	6.74	pKi	184	nM	Ki	Bioorg Med Chem (2010) 18: 728-736 [PMID:20036561]
ChEMBL	Displacement of [125I]iodo-(+/-)-cyanopindolol from human adrenergic beta2 receptor expressed in CHO cells after 3 hrs by radio-ligand binding assay	B	8.49	pKi	3.2	nM	Ki	Bioorg Med Chem Lett (2014) 24: 4341-4347 [PMID:25065493]
ChEMBL	Displacement of [3H]CGP12177 from human beta2 adrenoceptor	B	8.49	pKi	3.2	nM	Ki	Bioorg Med Chem Lett (2010) 20: 5302-5307 [PMID:20655218]
ChEMBL	Displacement of [3H]dihydroalprenolol from human beta2 adrenergic receptor expressing cell membrane by competition binding assay	B	8.6	pKi	2.51	nM	Ki	Bioorg Med Chem Lett (2014) 24: 2871-2876 [PMID:24835980]
ChEMBL	Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay	B	8.6	pKi	2.51	nM	Ki	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Displacement of [3H]-dihydroalprenolol from human beta2-adrenoceptor expressed in HEK cells after 4 hrs	B	8.62	pKi	2.4	nM	Ki	Bioorg Med Chem Lett (2011) 21: 1354-1358 [PMID:21310610]
ChEMBL	Displacement of [125I]-CYP from human beta2-adrenergic receptor expressed in COS-7 cells by gamma counting	B	8.82	pKi	1.5	nM	Ki	Bioorg Med Chem (2010) 18: 728-736 [PMID:20036561]
ChEMBL	Binding affinity for human beta-2 adrenergic receptor	B	9	pKi	1	nM	Ki	Bioorg Med Chem Lett (2004) 14: 4705-4710 [PMID:15324892]
ChEMBL	Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assay	B	9.41	pKi	0.39	nM	Ki	J Med Chem (2010) 53: 3675-3684 [PMID:20402514]
ChEMBL	Displacement of [3H]-CGP-12177 from human beta2-adrenergic receptor expressed in CHO cells after 60 mins by radioligand competition binding assay	B	9.6	pKi	0.25	nM	Ki	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
ChEMBL	Displacement of [3H]CGP12177 from human beta2 receptor expressed in CHO cells	B	9.74	pKi	0.18	nM	Ki	Bioorg Med Chem (2016) 24: 2641-2653 [PMID:27132867]
ChEMBL	Displacement of [3H]dihydroalprenolol from beta2-adrenoceptor after 90 mins by liquid scintillation counting	B	8.3	pIC50	5.01	nM	IC50	Bioorg Med Chem Lett (2012) 22: 1213-1218 [PMID:22178551]
ChEMBL	Agonist activity at human beta2 adrenoceptor expressed in H292 cells assessed as increase in cAMP accumulation after 60 mins by spectrophotometry	F	9.1	pEC50	0.79	nM	EC50	Bioorg Med Chem Lett (2012) 22: 689-695 [PMID:22079756]
ChEMBL	Agonist activity at beta2-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring Rluc2-117-GalphaS/GFP10-Ggamma/Gbeta1 assessed as activation of GalphaS incubated for 5 mins in presence of coelenterazine 400a by BRET assay	B	9.1	pEC50	0.79	nM	EC50	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
ChEMBL	Agonist activity at human adrenergic beta2 receptor expressed in H292 cells assessed as intracellular cAMP accumulation after 1 hr	F	9.1	pEC50	0.79	nM	EC50	Bioorg Med Chem Lett (2011) 21: 4027-4031 [PMID:21652207]
ChEMBL	Agonist activity at human adrenergic beta2 receptor expressed in H292 cells assessed as stimulation of cAMP accumulation after 60 mins	F	9.1	pEC50	0.79	nM	EC50	Bioorg Med Chem Lett (2011) 21: 4612-4616 [PMID:21723724]
ChEMBL	Agonist activity at human beta2 adrenoceptor expressed in CHO cells assessed as increase in intracellular cAMP level incubated for 1 hr by alphascreen technology	F	9.15	pEC50	0.71	nM	EC50	J Med Chem (2020) 63: 15218-15242 [PMID:33213146]
ChEMBL	Agonist activity at human beta2 receptor in BEAS-2B cells assessed as cAMP accumulation by radioimmunoassay	F	9.3	pEC50	0.5	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Agonist activity at beta2-adrenoceptor endogenously expressed in human BEAS-2B cells assessed as cAMP accumulation by homogeneous radioimmunoassay	F	9.3	pEC50	0.5	nM	EC50	Bioorg Med Chem Lett (2012) 22: 1213-1218 [PMID:22178551]
ChEMBL	Agonist activity at human beta2 adrenergic receptor in human BEAS-2B cells by cAMP accumulation assay	F	9.3	pEC50	0.5	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2871-2876 [PMID:24835980]
ChEMBL	Agonist activity at human beta2-adrenoceptor expressed in HEK cells assessed as increase of cAMP level after 10 mins by radioimmunoassay	F	9.48	pEC50	0.33	nM	EC50	Bioorg Med Chem Lett (2011) 21: 1354-1358 [PMID:21310610]
ChEMBL	Agonist activity at human beta2 adrenergic receptor assessed as increase in cAMP level by whole cell assay	F	9.49	pEC50	0.32	nM	EC50	J Med Chem (2010) 53: 3675-3684 [PMID:20402514]
ChEMBL	Agonist activity at human beta2 adrenergic receptor expressed in cells by cAMP accumulation assay	F	9.5	pEC50	0.32	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2871-2876 [PMID:24835980]
ChEMBL	Agonist activity at recombinant human beta2-adrenoceptor expressed in whole cells assessed as cAMP accumulation by homogeneous radioimmunoassay	F	9.5	pEC50	0.32	nM	EC50	Bioorg Med Chem Lett (2012) 22: 1213-1218 [PMID:22178551]
ChEMBL	Agonist activity at human recombinant beta2 receptor assessed as cAMP accumulation by radioimmunoassay and cell based assay	F	9.5	pEC50	0.32	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Agonist activity at human adrenergic beta2 receptor expressed in CHO cells assessed as cAMP accumulation	F	9.6	pEC50	0.25	nM	EC50	Bioorg Med Chem (2011) 19: 4192-4201 [PMID:21696967]
ChEMBL	Agonist activity at human beta2 adrenoceptor transfected in CHO cells assessed as cyclic AMP accumulation after 45 mins by fluorescence polarization assay	F	9.6	pEC50	0.25	nM	EC50	J Med Chem (2014) 57: 159-170 [PMID:24359185]
ChEMBL	Agonist activity at human cloned beta2 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation by beta-galactosidase based whole cell assay	F	9.6	pEC50	0.25	nM	EC50	J Med Chem (2009) 52: 2280-2288 [PMID:19317397]
ChEMBL	Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation after 30 to 45 mins	F	9.6	pEC50	0.25	nM	EC50	J Med Chem (2010) 53: 4522-4530 [PMID:20462258]
ChEMBL	Agonist activity at human beta2 receptor expressed in CHO cells assessed as cAMP accumulation	F	9.6	pEC50	0.25	nM	EC50	Bioorg Med Chem (2011) 19: 6026-6032 [PMID:21925889]
ChEMBL	Agonist activity at human beta2 adrenoreceptor overexpressed in HEK293 cells assessed as cAMP accumulation	F	9.87	pEC50	0.13	nM	EC50	Eur J Med Chem (2021) 224: 113697-113697 [PMID:34273662]
ChEMBL	Agonist activity at beta2-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring GFP/Rluc2-tagged beta-arrestin2 assessed as increase in beta-arrestin2 recruitment incubated for 5 mins in presence of GSK2 and coelenterazine 400a by BRET assay	B	9.9	pEC50	0.13	nM	EC50	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
GtoPdb	-	-	9.92	pEC50	0.12	nM	EC50	Br J Pharmacol (2010) 160: 1048-61 [PMID:20590599]
ChEMBL	Agonist activity at beta2-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring GFP/Rluc2-tagged beta-arrestin2 assessed as increase in beta-arrestin2 recruitment incubated for 5 mins in presence of GSK5 and coelenterazine 400a by BRET assay	B	10.1	pEC50	0.08	nM	EC50	J Med Chem (2019) 62: 5111-5131 [PMID:31042379]
ChEMBL	Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay	F	10.11	pEC50	0.08	nM	EC50	Bioorg Med Chem (2019) 27: 2306-2314 [PMID:30392952]
ChEMBL	Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as elevation in cAMP level after 1 hr by flashplate method	F	10.15	pEC50	0.07	nM	EC50	J Med Chem (2010) 53: 6640-6652 [PMID:20804199]
ChEMBL	Agonist activity at human recombinant beta-2 adrenoceptor expressed in CHO cells assessed as elevation of cAMP	F	10.15	pEC50	0.07	nM	EC50	Bioorg Med Chem Lett (2007) 17: 4012-4015 [PMID:17498952]
ChEMBL	Agonist activity at human recombinant adrenergic beta-2 receptor expressed in CHO cells assessed as elevation in cAMP levels	F	10.15	pEC50	0.07	nM	EC50	Bioorg Med Chem Lett (2007) 17: 6188-6191 [PMID:17897826]
ChEMBL	Agonist activity at human beta2 adrenoreceptor overexpressed in human HEK293 cells assessed as cAMP accumulation incubated for 60 mins by HTRF assay	F	10.35	pEC50	0.04	nM	EC50	Bioorg Med Chem (2020) 28: 115178-115178 [PMID:31753798]
Beta-2 adrenergic receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5414] [UniProtKB: Q8K4Z4]
ChEMBL	Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response after 30 mins	F	8.46	pIC50	3.5	nM	IC50	J Med Chem (2010) 53: 3675-3684 [PMID:20402514]
ChEMBL	Agonist activity at adrenergic beta2 receptor in electrically-stimulated Dunkin-Hartley guinea pig tracheal strip assessed as inhibition of contraction	B	8.46	pIC50	3.5	nM	IC50	Bioorg Med Chem Lett (2014) 24: 4341-4347 [PMID:25065493]
ChEMBL	Agonist activity at beta2 receptor in guinea pig trachea assessed as slow onset of inhibition of electrically stimulated contraction	B	7.5	pEC50	31.62	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Agonist activity at adrenergic beta2 receptor in guinea pig trachea assessed as inhibition of electrically-stimulated contraction	F	8.3	pEC50	5.01	nM	EC50	Bioorg Med Chem (2011) 19: 4192-4201 [PMID:21696967]
ChEMBL	Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response	F	8.3	pEC50	5.01	nM	EC50	Bioorg Med Chem (2011) 19: 6026-6032 [PMID:21925889]
ChEMBL	Agonist activity at beta2 adrenoceptor in guinea pig trachea assessed as inhibition of histamine-induced contraction	B	8.57	pEC50	2.7	nM	EC50	Bioorg Med Chem Lett (2015) 25: 5121-5126 [PMID:26471092]
β3-adrenoceptor/Beta-3 adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL246] [GtoPdb: 30] [UniProtKB: P13945]
ChEMBL	Agonist activity at human cloned beta3 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation by beta-galactosidase based whole cell assay	F	5.9	pEC50	1258.93	nM	EC50	J Med Chem (2009) 52: 2280-2288 [PMID:19317397]
ChEMBL	Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation after 30 to 45 mins	F	5.9	pEC50	1258.93	nM	EC50	J Med Chem (2010) 53: 4522-4530 [PMID:20462258]
ChEMBL	Agonist activity at human adrenergic beta3 receptor expressed in CHO cells assessed as cAMP accumulation	F	5.9	pEC50	1258.93	nM	EC50	Bioorg Med Chem (2011) 19: 4192-4201 [PMID:21696967]
ChEMBL	Agonist activity at human beta3 receptor expressed in CHO cells assessed as cAMP accumulation	F	5.9	pEC50	1258.93	nM	EC50	Bioorg Med Chem (2011) 19: 6026-6032 [PMID:21925889]
ChEMBL	Agonist activity at human beta3 adrenoceptor transfected in CHO cells assessed as cyclic AMP accumulation after 45 mins by fluorescence polarization assay	B	5.9	pEC50	1258.93	nM	EC50	J Med Chem (2014) 57: 159-170 [PMID:24359185]
ChEMBL	Agonist activity at human recombinant beta3 receptor assessed as cAMP accumulation by radioimmunoassay and cell based assay	F	6	pEC50	1000	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2625-2630 [PMID:24813741]
ChEMBL	Agonist activity at human beta3 adrenergic receptor expressed in cells by cAMP accumulation assay	F	6	pEC50	1000	nM	EC50	Bioorg Med Chem Lett (2014) 24: 2871-2876 [PMID:24835980]
D2 receptor/Dopamine D2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416]
ChEMBL	Displacement of [3H]spiperone from human D2S receptor expressed in CHO cells	B	4.49	pKi	32000	nM	Ki	Bioorg Med Chem (2016) 24: 2641-2653 [PMID:27132867]
D3 receptor/Dopamine D3 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL234] [GtoPdb: 216] [UniProtKB: P35462]
ChEMBL	Displacement of [125I]7-HO-PIPAT from human D3R expressed in HEK cells	B	5.98	pKi	1049	nM	Ki	Bioorg Med Chem Lett (2014) 24: 4341-4347 [PMID:25065493]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]