Structure and Physico-chemical Properties
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Molecular properties generated using the CDK |
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Classification  |
|
| Compound class | Synthetic organic |
| Approved drug? | Yes (FDA (1996)) |
| Withdrawn drug? | Yes |
| IUPAC Name |
| 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid |
| International Nonproprietary Names |
|
| INN number | INN |
| 5950 | amlexanox |
| Synonyms |
| AA-673 | Amlexanox® | Aphthasol® | CHX-3673 |
| Comments |
| Amlexanox has anti-inflammatory [1], antiallergic and immunomodulatory actions [2]. Proposed to inhibit IKKδ and TBK1, albeit with low potency [5]. |
| Database Links |
|
| CAS Registry No. | 68302-57-8 |
| ChEMBL Ligand | CHEMBL1096 |
| DrugBank Ligand | DB01025 |
| GtoPdb PubChem SID | 178103690 |
| PubChem CID | 2161 |
| RCSB PDB Ligand | ANW |
| Search Google for chemical match using the InChIKey | SGRYPYWGNKJSDL-UHFFFAOYSA-N |
| Search Google for chemicals with the same backbone | SGRYPYWGNKJSDL |
| Search PubMed clinical trials | amlexanox |
| Search PubMed titles | amlexanox |
| Search PubMed titles/abstracts | amlexanox |
| Search UniChem for chemical match using the InChIKey | SGRYPYWGNKJSDL-UHFFFAOYSA-N |
| Search UniChem for chemicals with the same backbone | SGRYPYWGNKJSDL |
| Wikipedia | Amlexanox |
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Sponsored products disclaimer
Product supplier links are provided as a service to assist in identifying commercial suppliers of reagents that are mentioned on the IUPHAR/BPS Guide to PHARMACOLOGY database website, and do not imply their endorsement by NC-IUPHAR.
Links are provided in return for sponsorship, used to fund improvements to this database. The sponsorship account is managed and audited by the University of Edinburgh, a charitable body registered in Scotland, SC005336. If you are interested in sponsoring the database, please contact us.
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Amlexanox
Cat. No. 4857 |
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