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The IUPHAR Guide to IMMUNOPHARMACOLOGY ligand list

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GtoImmuPdb ligands only: Ligands which are included in the World Health Organization (WHO) Model List of Essential Medicines (24th List, 2025).
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A   B   C   D   E   F   G   H   I   L   M   N   P   R   S   T   U   V  

Ligand name ID Synonyms
A Back to top
adalimumab Approved drug Immunopharmacology Ligand 4860 D2E7, Humira®
aspirin Approved drug PDB Ligand Immunopharmacology Ligand 4139 Acetophen®, acetylsalicylic acid, Aspirin®
atracurium Approved drug Immunopharmacology Ligand 9537 atracurium besilate, atracurium dibesylate, BW 33A, Tracrium®
azathioprine Approved drug Immunopharmacology Ligand 7120 Azasan®, BW-57-322, Imuran®, Jayempi®
azithromycin Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6510
 
B Back to top
beclometasone Approved drug PDB Ligand Immunopharmacology Ligand 7059 beclomethasone, SCH-18020W
betamethasone Approved drug Immunopharmacology Ligand 7061 SCH-4831
bortezomib Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6391 peptide boronate, PS-341, Velcade®
budesonide Approved drug Immunopharmacology Ligand 7434 Entocort®, Eohilia® (budesonide oral suspension), Jorveza®, Pulmicort®, S-1320, Uceris®
 
C Back to top
certolizumab pegol Approved drug Immunopharmacology Ligand 6774 CDP870, Cimzia®, PHA 738144
cetirizine Approved drug Immunopharmacology Ligand 1222 Reactine®, Zyrtec®
chloroquine Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 5535 Aralen®, chloraquine, Malaquin®
ciclesonide Approved drug Immunopharmacology Ligand 7469 Alvesco®, Omnaris®, RPR-251526
clofazimine Approved drug Immunopharmacology Ligand 9184 Lamprene®
cortisol Approved drug PDB Ligand Immunopharmacology Ligand 2868 Acticort®, Efmody®, Plenadren®
cyclosporin A Approved drug Immunopharmacology Ligand 1024 ciclosporin, cyclosporine, cyclosporine A, Ikervis® (opthalmic solution), Neoral®, Sandimmun®, Verkazia® (opthalmic solution)
 
D Back to top
dasatinib Approved drug PDB Ligand Immunopharmacology Ligand 5678 BMS 345825, BMS 354825, BMS 35482513, Sprycel®
dexamethasone Approved drug PDB Ligand Immunopharmacology Ligand 2768 Decadron®, desametasone, fluormethylprednisolone
dopamine Approved drug PDB Ligand Immunopharmacology Ligand 940 3-hydroxytyramine
doxycycline Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6464 BMY-28689, Monodox®, Vibramycin®
 
E Back to top
etanercept Approved drug Immunopharmacology Ligand 6789 Enbrel®, Rhu Tnfr:Fc, TNFR-Fc, TNR 001
everolimus Approved drug Immunopharmacology Ligand 5889 Afinitor®, Certican®, RAD-001, RAD001, rapamycin, 42-O-(2-hydroxyethyl)-, Zortress®
 
F Back to top
fexofenadine Approved drug Immunopharmacology Ligand 4819 Allegra®, fexofenadine HCl
filgrastim Approved drug Immunopharmacology Ligand 6968 Filcad®, Imumax ®, R-METHUG-CSF
flunisolide Approved drug Immunopharmacology Ligand 7076 AeroBid®, RS-3999
fluticasone Approved drug Immunopharmacology Ligand 6699 Advair®, Avamys®, Flovent HFA®, Veramyst®
fluticasone furoate Approved drug PDB Ligand Immunopharmacology Ligand 10892 Arnuity Ellipta, Avamys, FF, Flonase Sensimist, Veramyst
formoterol Approved drug Immunopharmacology Ligand 3465 BD-40A, CGP-25827A, Foradil®, Oxeze/Oxis®, YM-08316
 
G Back to top
glycopyrrolate Approved drug Immunopharmacology Ligand 7459 AHR-504, Qbrexza® (glycopyrronium cloth), Robinul®, Seebri Neohaler®, Tovanor Breezhaler®
golimumab Approved drug Immunopharmacology Ligand 6776 CNTO-148, CNTO148, Simponi®
 
H Back to top
hydroxychloroquine Approved drug Immunopharmacology Ligand Antimalarial Ligand 7198 Dolquine®, Plaquenil®
 
I Back to top
ibrutinib Approved drug PDB Ligand Immunopharmacology Ligand 6912 Imbruvica®, PCI-32765
ibuprofen Approved drug Immunopharmacology Ligand 2713 Advil®, Brufen®, ibuprofen lysine, ibuprofen sodium, Motrin®, Nurofen®, U-18573
imatinib Approved drug PDB Ligand Immunopharmacology Ligand 5687 CGP 57148, Gleevec®, Glivec®, STI571
indomethacin Approved drug PDB Ligand Immunopharmacology Ligand 1909 Indocid®, Indocin®
infliximab Approved drug Immunopharmacology Ligand 5004 cA2, Inflectra®, Remicade®, Remsima®, SB2, TA-650, Zymfentra® (subcutaneous formulation)
ipratropium Approved drug Immunopharmacology Ligand 325 Atrovent®, Ipraxa®
 
L Back to top
lenalidomide Approved drug Immunopharmacology Ligand 7331 CC-5013, CDC-501, Revlimid®
loratadine Approved drug Immunopharmacology Ligand 7216 Claritin®, SCH-29851
lovastatin Approved drug PDB Ligand Immunopharmacology Ligand 2739 (+)-mevinolin, 6α-methylcompactin, Mevacor®
 
M Back to top
metformin Approved drug PDB Ligand Immunopharmacology Ligand 4779 Glucophage®, LA-6023
methimazole Approved drug PDB Ligand Immunopharmacology Ligand 6649 Tapazole®, Thiamazole®
methotrexate Approved drug PDB Ligand Immunopharmacology Ligand 4815 Abitrexate®, amethopterin, Nordimet®, Rasuvo®
methylprednisolone Approved drug Immunopharmacology Ligand 7088 Medrol®, U-67590A
mifepristone Approved drug PDB Ligand Immunopharmacology Ligand 2805 Mifeprex®, RU-486, RU486
miltefosine Approved drug Immunopharmacology Ligand 11355 D-18506, D18506, Impavido®, Miltex®, n-hexadecylphosphorylcholine
mometasone Approved drug Immunopharmacology Ligand 9029 Elocon® (topical), Nasonex®
 
N Back to top
nivolumab Approved drug Immunopharmacology Ligand 7335 BMS-936558, MDX-1106, ONO-4538, Opdivo®
 
P Back to top
pembrolizumab Approved drug Immunopharmacology Ligand 7499 Keytruda Qlex® (pembrolizumab + berahyaluronidase alfa-pmph; for subcutaneous injection), Keytruda®, lambrolizumab, MK-3475
penicillamine Approved drug PDB Ligand Immunopharmacology Ligand 7264 Cuprimine®
PGE2 Approved drug PDB Ligand Immunopharmacology Ligand 1883 Cervidil®, minprositin E2, minprostin E2, Propess®, prostaglandin E2
prednisolone Approved drug PDB Ligand Immunopharmacology Ligand 2866 DELTA.1-Cortisol, Orapred®, Pediapred®
prednisone Approved drug Immunopharmacology Ligand 7096 Lodotra®, Sterapred®
 
R Back to top
rituximab Approved drug Immunopharmacology Ligand 6780 HSDB 7455, IDEC-C2B8, MabThera®, Rituxan®
 
S Back to top
salbutamol Approved drug Immunopharmacology Ligand 558 albuterol, SCH-13949W, Ventolin®
salicylic acid Approved drug PDB Ligand Immunopharmacology Ligand 4306 Bazuka Extra Strength Gel®, salicylate
salmeterol Approved drug Immunopharmacology Ligand 559 GR 33343X, Serevent®
 
T Back to top
thalidomide Approved drug Immunopharmacology Ligand 7327 K-17
tiotropium Approved drug Immunopharmacology Ligand 367 BA-679-BR, Spiriva®
triamcinolone Approved drug Immunopharmacology Ligand 2870 fluoxiprednisolone, Kenalog®, Nasacort®
 
U Back to top
umeclidinium Approved drug Immunopharmacology Ligand 7354 GSK573719A, Incruse Ellipta®
 
V Back to top
vilanterol Approved drug Immunopharmacology Ligand 7353 GW642444X