brentuximab vedotin

Ligand id: 6772

Name: brentuximab vedotin

Compound class Antibody
Approved drug? Yes (FDA (2011), EMA (2012))
International Nonproprietary Names
INN number INN
9144 brentuximab vedotin
Adcetris® | anti-CD30 ADC SGN-35 | SGN 35
Antibody-drug conjugate (ADC) that combines an anti-CD30 antibody and the drug monomethyl auristatin E (MMAE). The PubChem ID for the MMAE component compound is CID 11542188. The invention of this ADC is claimed in patent US7090843 [4] and the original article describing the parent antibody (C10 or AC10) is [1].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Database Links
Specialist databases
IMGT/mAb-DB 324
Other databases
GtoPdb PubChem SID 178103378
PubChem SID 178103378
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Wikipedia Brentuximab_vedotin