Ligand id: 7674

Name: benralizumab

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Compound class Antibody
Approved drug? Yes (FDA (2017), EMA (2018))
International Nonproprietary Names
INN number INN
9233 benralizumab
BIW-8405 | Fasenra® | KHK4563 | MEDI-563
Benralizumab is a humanized, afucosylated mAb targeting the IL5Rα which is expressed by cells of the eosinophil lineage. The antibody is afucosylated (ie has fucose containing oligosaccharide side-chains removed) to improve structure, stability, and biological function.
Peptide sequence information for this antibody is available from its IMGT/mAb-DB link.
Database Links
Specialist databases
IMGT/mAb-DB 334
Other databases
ChEMBL Ligand CHEMBL1742991
GtoPdb PubChem SID 223366009
Search PubMed clinical trials benralizumab
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Wikipedia Benralizumab