ChEMBL ligand: CHEMBL424 (Duofilm, Edinburgh, Salatac, Bazuka, Necol, Dr. scholl's wart remover kit, Acnisal, Posalfilin, NSC-180, Salactol, Duoplant, Phytex, Dr. scholl's corn removers, Toepedo, Ionil, Salicylic acid soap, Compound v, Duofilm wart remover, Ionil-plus, Wartex, Jadit, Saligel, Stri-dex, Advanced pain relief callus removers, Compound w, Erytex, Freezone, K-557, Dr. scholl's callus removers, Clear away wart remover, Keralyt, Lamivudine related compound salicylic acid, Cuplex verruca, Salicylic acid, 2-Hydroxy-benzoic acid, Advanced pain relief com removers, FEMA NO. 3985, Lamivudine impurity, salicylic acid-, Phytocil, Phiso-clear, Salicylic Acid, Noxacorn, Metanium, Pyralvex, Gppe paint, Occlusal, Salicylic acid rs, Thwart, Verrugon)
Beta amyloid A4 protein in Human [ChEMBL: CHEMBL2487] [UniProtKB: P05067] There should be some charts here, you may need to enable JavaScript!
Carbonic anhydrase 15 in Mouse [ChEMBL: CHEMBL5973] [UniProtKB: Q99N23] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 1/Carbonic anhydrase I in Human [ChEMBL: CHEMBL261] [GtoPdb: 2597] [UniProtKB: P00915] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 2/Carbonic anhydrase II in Human [ChEMBL: CHEMBL205] [GtoPdb: 3092] [UniProtKB: P00918] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 4/Carbonic anhydrase IV in Human [ChEMBL: CHEMBL3729] [GtoPdb: 2599] [UniProtKB: P22748] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 9/Carbonic anhydrase IX in Human [ChEMBL: CHEMBL3594] [GtoPdb: 3055] [UniProtKB: Q16790] There should be some charts here, you may need to enable JavaScript!
Carbonic anhydrase VI in Human [ChEMBL: CHEMBL3025] [UniProtKB: P23280] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 7/Carbonic anhydrase VII in Human [ChEMBL: CHEMBL2326] [GtoPdb: 2749] [UniProtKB: P43166] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 12/Carbonic anhydrase XII in Human [ChEMBL: CHEMBL3242] [GtoPdb: 2747] [UniProtKB: O43570] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 13/Carbonic anhydrase XIII in Mouse [ChEMBL: CHEMBL2186] [GtoPdb: 2748] [UniProtKB: Q9D6N1] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 14/Carbonic anhydrase XIV in Human [ChEMBL: CHEMBL3510] [GtoPdb: 2598] [UniProtKB: Q9ULX7] There should be some charts here, you may need to enable JavaScript!
High mobility group protein B1 in Human [ChEMBL: CHEMBL2311236] [UniProtKB: P09429] There should be some charts here, you may need to enable JavaScript!
Nicotinate phosphoribosyltransferase in Human [ChEMBL: CHEMBL4523354] [UniProtKB: Q6XQN6] There should be some charts here, you may need to enable JavaScript!
OAT6/Solute carrier family 22 member 20 in Mouse [ChEMBL: CHEMBL5269] [GtoPdb: 1037] [UniProtKB: Q80UJ1] There should be some charts here, you may need to enable JavaScript!
Tyrosinase in Agaricus bisporus [ChEMBL: CHEMBL3318] [UniProtKB: O42713] There should be some charts here, you may need to enable JavaScript!
ASIC3 in Human [GtoPdb: 686] [UniProtKB: Q9UHC3] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Beta amyloid A4 protein in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2487] [UniProtKB: P05067]
ChEMBL	Inhibitory activity against binding of [125I]IMSB to amyloid beta in brain	B	5.74	pKi	>1800	nM	Ki	J. Med. Chem. (2001) 44: 2270-2275 [PMID:11428920]
Carbonic anhydrase 15 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5973] [UniProtKB: Q99N23]
ChEMBL	Inhibition of mouse recombinant carbonic anhydrase 15 by stopped-flow CO2 hydrase assay	B	5.14	pKi	7200	nM	Ki	Bioorg. Med. Chem. Lett. (2008) 18: 3593-3596 [PMID:18501600]
carbonic anhydrase 1/Carbonic anhydrase I in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL261] [GtoPdb: 2597] [UniProtKB: P00915]
ChEMBL	Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assay	B	5	pKi	9920	nM	Ki	Bioorg. Med. Chem. Lett. (2008) 18: 3593-3596 [PMID:18501600]
ChEMBL	Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydration assay	B	5	pKi	9900	nM	Ki	Bioorg. Med. Chem. (2008) 16: 7424-7428 [PMID:18579385]
ChEMBL	Inhibition of human carbonic anhydrase 1 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay	B	5	pKi	9900	nM	Ki	Bioorg. Med. Chem. Lett. (2015) 25: 5636-5641 [PMID:26520662]
carbonic anhydrase 2/Carbonic anhydrase II in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL205] [GtoPdb: 3092] [UniProtKB: P00918]
ChEMBL	Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay	B	5.15	pKi	7120	nM	Ki	Bioorg. Med. Chem. Lett. (2008) 18: 3593-3596 [PMID:18501600]
ChEMBL	Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydration assay	B	5.15	pKi	7100	nM	Ki	Bioorg. Med. Chem. (2008) 16: 7424-7428 [PMID:18579385]
ChEMBL	Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay	B	5.15	pKi	7100	nM	Ki	Bioorg. Med. Chem. Lett. (2015) 25: 5636-5641 [PMID:26520662]
carbonic anhydrase 4/Carbonic anhydrase IV in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3729] [GtoPdb: 2599] [UniProtKB: P22748]
ChEMBL	Inhibition of human carbonic anhydrase 4 by stopped-flow CO2 hydration assay	B	4.95	pKi	11100	nM	Ki	Bioorg. Med. Chem. (2008) 16: 7424-7428 [PMID:18579385]
carbonic anhydrase 9/Carbonic anhydrase IX in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3594] [GtoPdb: 3055] [UniProtKB: Q16790]
ChEMBL	Inhibition of human carbonic anhydrase 9 catalytic domain by stopped-flow CO2 hydration assay	B	4.1	pKi	78700	nM	Ki	Bioorg. Med. Chem. (2008) 16: 7424-7428 [PMID:18579385]
ChEMBL	Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay	B	4.1	pKi	78700	nM	Ki	Bioorg. Med. Chem. Lett. (2015) 25: 5636-5641 [PMID:26520662]
Carbonic anhydrase VI in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3025] [UniProtKB: P23280]
ChEMBL	Inhibition of human carbonic anhydrase 6 by stopped-flow CO2 hydration assay	B	4.92	pKi	11900	nM	Ki	Bioorg. Med. Chem. (2008) 16: 7424-7428 [PMID:18579385]
carbonic anhydrase 7/Carbonic anhydrase VII in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2326] [GtoPdb: 2749] [UniProtKB: P43166]
ChEMBL	Inhibition of human carbonic anhydrase 7 by stopped-flow CO2 hydration assay	B	4.09	pKi	82100	nM	Ki	Bioorg. Med. Chem. (2008) 16: 7424-7428 [PMID:18579385]
carbonic anhydrase 12/Carbonic anhydrase XII in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3242] [GtoPdb: 2747] [UniProtKB: O43570]
ChEMBL	Inhibition of human carbonic anhydrase 12 catalytic domain by stopped-flow CO2 hydration assay	B	5.06	pKi	8800	nM	Ki	Bioorg. Med. Chem. (2008) 16: 7424-7428 [PMID:18579385]
carbonic anhydrase 13/Carbonic anhydrase XIII in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2186] [GtoPdb: 2748] [UniProtKB: Q9D6N1]
ChEMBL	Inhibition of mouse carbonic anhydrase 13 by stopped-flow CO2 hydration assay	B	4.17	pKi	67000	nM	Ki	Bioorg. Med. Chem. (2008) 16: 7424-7428 [PMID:18579385]
carbonic anhydrase 14/Carbonic anhydrase XIV in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3510] [GtoPdb: 2598] [UniProtKB: Q9ULX7]
ChEMBL	Inhibition of human carbonic anhydrase 14 by stopped-flow CO2 hydration assay	B	4.3	pKi	49800	nM	Ki	Bioorg. Med. Chem. (2008) 16: 7424-7428 [PMID:18579385]
High mobility group protein B1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2311236] [UniProtKB: P09429]
ChEMBL	Binding affinity to recombinant HMGB1 box A (unknown origin)	B	6	pKd	1000	nM	Kd	J Med Chem (2018) 61: 5093-5107 [PMID:29268019]
ChEMBL	Binding affinity to recombinant HMGB1 box B (unknown origin)	B	6	pKd	1000	nM	Kd	J Med Chem (2018) 61: 5093-5107 [PMID:29268019]
Nicotinate phosphoribosyltransferase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4523354] [UniProtKB: Q6XQN6]
ChEMBL	Inhibition of NAPRT (unknown origin)	B	9.8	pKi	0.16	nM	Ki	WO-2017162840-A1. Sensitization of cancer cells to nampt inhibitors by nicotinic acid phosphoribosyltransferase neutralization (null)
OAT6/Solute carrier family 22 member 20 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5269] [GtoPdb: 1037] [UniProtKB: Q80UJ1]
ChEMBL	Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr	B	4.36	pKi	44000	nM	Ki	J. Biol. Chem. (2007) 282: 23841-23853 [PMID:17553798]
ChEMBL	Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr	B	4.36	pKi	43651.58	nM	Ki	J. Biol. Chem. (2007) 282: 23841-23853 [PMID:17553798]
Tyrosinase in Agaricus bisporus (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3318] [UniProtKB: O42713]
ChEMBL	Inhibition of mushroom tyrosinase after 10 mins	B	4	pIC50	100000	nM	IC50	J. Med. Chem. (2011) 54: 591-602 [PMID:21189019]
ASIC3 in Human [GtoPdb: 686] [UniProtKB: Q9UHC3]
GtoPdb	-	-	3.6	pIC50	260000	nM	IC50	J Neurosci (2001) 21: 8026-33 [PMID:11588175]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]