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ChEMBL ligand: CHEMBL1201823 (Abatacept, Abatacept (genetical recombination), Abatacept recombinant, BMS-188667, CTLA4-IGG4M, Orencia, Orencia clickject, RG-1046, RG-2077) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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CD80 in Human [GtoPdb: 2744] [UniProtKB: P33681] | ||||||||
GtoPdb | Measuring binding of 125I-labeled B7Ig fusion protein to immobilized abatacept. | - | 7.92 | pKd | ~12 | nM | Kd |
Expert Rev Clin Immunol (2013) 9: 599-621 [PMID:23899231]; J Exp Med (1991) 174: 561-9 [PMID:1714933] |
CD86 in Human [GtoPdb: 2745] [UniProtKB: P42081] | ||||||||
GtoPdb | Measuring binding of 125I-labeled B7Ig fusion protein to immobilized abatacept. | - | 7.92 | pKd | ~12 | nM | Kd |
Expert Rev Clin Immunol (2013) 9: 599-621 [PMID:23899231]; J Exp Med (1991) 174: 561-9 [PMID:1714933] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]