Synonyms: ALKS-8700 | ALKS8700 | BIIB098 | Vumerity®
diroximel fumarate is an approved drug (FDA (2019), EMA (2021))
Compound class:
Synthetic organic
Comment: Diroximel fumarate is a novel oral fumarate prodrug. It is rapidly converted to monomethyl fumarate, which is the same active metabolite of dimethyl fumarate.
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Classification | |
Compound class | Synthetic organic |
Approved drug? | Yes (FDA (2019), EMA (2021)) |
Is prodrug? | Yes |
Active form | monomethyl fumarate |
IUPAC Name |
4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate |
International Nonproprietary Names | |
INN number | INN |
10356 | diroximel fumarate |
Synonyms |
ALKS-8700 | ALKS8700 | BIIB098 | Vumerity® |
Database Links | |
CAS Registry No. | 1577222-14-0 (source: WHO INN record) |
ChEMBL Ligand | CHEMBL3989944 |
GtoPdb PubChem SID | 387065607 |
PubChem CID | 73330464 |
Search Google for chemical match using the InChIKey | YIMYDTCOUQIDMT-SNAWJCMRSA-N |
Search Google for chemicals with the same backbone | YIMYDTCOUQIDMT |
Search PubMed clinical trials | diroximel fumarate |
Search PubMed titles | diroximel fumarate |
Search PubMed titles/abstracts | diroximel fumarate |
UniChem Compound Search for chemical match using the InChIKey | YIMYDTCOUQIDMT-SNAWJCMRSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | YIMYDTCOUQIDMT-SNAWJCMRSA-N |