CCL4   

GtoPdb Ligand ID: 757

Synonyms: HC21 | macrophage inflammatory protein-1β | MIP-1β
Comment: CCL4 is a CC family chemokine more commonly referred to as macrophage inflammatory protein-1β or MIP-1β. It acts in a dimer with CCL3 (MIP-1α) [1].
Species: Human
Natural/Endogenous Targets
Target
CCR1
CCR5
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CCR5 Hs Agonist Full agonist 9.4 – 9.6 pKi - 6,8
pKi 9.4 – 9.6 [6,8]
CCR1 Hs Antagonist Antagonist 7.1 – 7.8 pKi - 3,5
pKi 7.1 – 7.8 [3,5]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference