CCL4   Click here for help

GtoPdb Ligand ID: 757

Synonyms: HC21 | macrophage inflammatory protein-1β | MIP-1β
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: CCL4 is a CC family chemokine more commonly referred to as macrophage inflammatory protein-1β or MIP-1β. It acts in a dimer with CCL3 (MIP-1α) [1].
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Chemokines
Synonyms Click here for help
HC21 | macrophage inflammatory protein-1β | MIP-1β
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
CCL4 C-C motif chemokine ligand 4 Human chemokine (C-C motif) ligand 4 Act-2, AT744.1, chemokine (C-C motif) ligand 4, LAG1, MIP-1-beta, SCYA4, small inducible cytokine A4 (homologous to mouse Mip-1b)
Database Links Click here for help
Specialist databases
GPCRdb Ligand CCL4
Other databases
Ensembl Gene ENSG00000129277 (Hs)
Entrez Gene 6351 (Hs)
GtoPdb PubChem SID 135651687
Human Protein Atlas ENSG00000129277 (Hs)
OMIM 182284
RefSeq Protein NP_002975
UniProtKB P13236 (Hs)
Wikipedia CCL4 (Hs)