CCL5   Click here for help

GtoPdb Ligand ID: 758

Synonyms: eosinophil chemotactic cytokine [EoCP] | regulated upon activation normal T cell expressed and secreted (RANTES)
Immunopharmacology Ligand
Comment: CCL5 (also known as RANTES- an acronym for regulated on activation, normal T cell expressed and secreted) is a CC family chemokine, that has HIV suppressive activity, as do the related CD8+ T cell chemokines CCL3 and CCL4.
Species: Human
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Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Chemokines
Synonyms Click here for help
eosinophil chemotactic cytokine [EoCP] | regulated upon activation normal T cell expressed and secreted (RANTES)
Medical Relevance
Many diseases have been associated to certain RANTES polymorphisms. For further information see GeneRIFs
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
CCL5 C-C motif chemokine ligand 5 Human chemokine (C-C motif) ligand 5 beta-chemokine RANTES, chemokine (C-C motif) ligand 5, D17S136E, MGC17164, RANTES, regulated upon activation, normally T-expressed, and presumably secreted, SCYA5, SISd, SIS-delta, small inducible cytokine A5 (RANTES), small inducible cytokine subfamily A (Cys-Cys), member 5, T-cell specific protein p288, T-cell specific RANTES protein, TCP228
Database Links Click here for help
Specialist databases
GPCRdb Ligand CCL5
Other databases
Ensembl Gene ENSG00000161570 (Hs)
Entrez Gene 6352 (Hs)
GtoPdb PubChem SID 135651690
Human Protein Atlas ENSG00000161570 (Hs)
OMIM 187011
RefSeq Protein NP_002976
UniProtKB P13501 (Hs)
Wikipedia CCL5 (Hs)