ChEMBL ligand: CHEMBL2436978
protein kinase AMP-activated non-catalytic subunit beta 2/protein kinase AMP-activated non-catalytic subunit gamma 1/protein kinase AMP-activated catalytic subunit alpha 2/protein kinase AMP-activated catalytic subunit alpha 1/protein kinase AMP-activated non-catalytic subunit gamma 3/protein kinase AMP-activated non-catalytic subunit gamma 2/protein kinase AMP-activated non-catalytic subunit beta 1/AMP-activated protein kinase, AMPK in Human [ChEMBL: CHEMBL2096907] [GtoPdb: 1544, 1545, 1542, 1541, 1547, 1546, 1543] [UniProtKB: O43741, P54619, P54646, Q13131, Q9UGI9, Q9UGJ0, Q9Y478] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase 8/c-Jun N-terminal kinase 1 in Human [ChEMBL: CHEMBL2276] [GtoPdb: 1496] [UniProtKB: P45983] There should be some charts here, you may need to enable JavaScript!
cyclin dependent kinase 1/Cyclin-dependent kinase 1 in Human [ChEMBL: CHEMBL308] [GtoPdb: 1961] [UniProtKB: P06493] There should be some charts here, you may need to enable JavaScript!
cyclin dependent kinase 2/Cyclin-dependent kinase 2 in Human [ChEMBL: CHEMBL301] [GtoPdb: 1973] [UniProtKB: P24941] There should be some charts here, you may need to enable JavaScript!
glycogen synthase kinase 3 beta/Glycogen synthase kinase-3 beta in Human [ChEMBL: CHEMBL262] [GtoPdb: 2030] [UniProtKB: P49841] There should be some charts here, you may need to enable JavaScript!
MET proto-oncogene, receptor tyrosine kinase/Hepatocyte growth factor receptor in Human [ChEMBL: CHEMBL3717] [GtoPdb: 1815] [UniProtKB: P08581] There should be some charts here, you may need to enable JavaScript!
Kv11.1/HERG in Human [ChEMBL: CHEMBL240] [GtoPdb: 572] [UniProtKB: Q12809] There should be some charts here, you may need to enable JavaScript!
component of inhibitor of nuclear factor kappa B kinase complex/Inhibitor of nuclear factor kappa B kinase alpha subunit in Human [ChEMBL: CHEMBL3476] [GtoPdb: 1989] [UniProtKB: O15111] There should be some charts here, you may need to enable JavaScript!
inhibitor of nuclear factor kappa B kinase subunit beta/Inhibitor of nuclear factor kappa B kinase beta subunit in Human [ChEMBL: CHEMBL1991] [GtoPdb: 2039] [UniProtKB: O14920] There should be some charts here, you may need to enable JavaScript!
Insulin-like growth factor I receptor in Human [ChEMBL: CHEMBL1957] [GtoPdb: 1801] [UniProtKB: P08069] There should be some charts here, you may need to enable JavaScript!
Insulin receptor in Human [ChEMBL: CHEMBL1981] [GtoPdb: 1800] [UniProtKB: P06213] There should be some charts here, you may need to enable JavaScript!
leucine rich repeat kinase 2/Leucine-rich repeat serine/threonine-protein kinase 2 in Human [ChEMBL: CHEMBL1075104] [GtoPdb: 2059] [UniProtKB: Q5S007] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase 1/MAP kinase ERK2 in Human [ChEMBL: CHEMBL4040] [GtoPdb: 1495] [UniProtKB: P28482] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase 14/MAP kinase p38 alpha in Human [ChEMBL: CHEMBL260] [GtoPdb: 1499] [UniProtKB: Q16539] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase kinase kinase 10/Mitogen-activated protein kinase kinase kinase 10 in Human [ChEMBL: CHEMBL2873] [GtoPdb: 2070] [UniProtKB: Q02779] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase kinase kinase 11/Mitogen-activated protein kinase kinase kinase 11 in Human [ChEMBL: CHEMBL2708] [GtoPdb: 2071] [UniProtKB: Q16584] mitogen-activated protein kinase kinase kinase 11/Mitogen-activated protein kinase kinase kinase 11 in Mouse [ChEMBL: CHEMBL2434817] [GtoPdb: 2071] [UniProtKB: Q80XI6] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase kinase kinase 2/Mitogen-activated protein kinase kinase kinase 2 in Human [ChEMBL: CHEMBL5914] [GtoPdb: 2077] [UniProtKB: Q9Y2U5] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase kinase kinase 9/Mitogen-activated protein kinase kinase kinase 9 in Human [ChEMBL: CHEMBL2872] [GtoPdb: 2084] [UniProtKB: P80192] There should be some charts here, you may need to enable JavaScript!
neurotrophic receptor tyrosine kinase 1/Nerve growth factor receptor Trk-A in Human [ChEMBL: CHEMBL2815] [GtoPdb: 1817] [UniProtKB: P04629] There should be some charts here, you may need to enable JavaScript!
neurotrophic receptor tyrosine kinase 2/Neurotrophic tyrosine kinase receptor type 2 in Human [ChEMBL: CHEMBL4898] [GtoPdb: 1818] [UniProtKB: Q16620] There should be some charts here, you may need to enable JavaScript!
Protein delta homolog 1 in Human [ChEMBL: CHEMBL5671] [UniProtKB: P80370] There should be some charts here, you may need to enable JavaScript!
Rho associated coiled-coil containing protein kinase 1/Rho-associated protein kinase 1 in Human [ChEMBL: CHEMBL3231] [GtoPdb: 1503] [UniProtKB: Q13464] There should be some charts here, you may need to enable JavaScript!
Rho associated coiled-coil containing protein kinase 2/Rho-associated protein kinase 2 in Human [ChEMBL: CHEMBL2973] [GtoPdb: 1504] [UniProtKB: O75116] There should be some charts here, you may need to enable JavaScript!
aurora kinase A/Serine/threonine-protein kinase Aurora-A in Human [ChEMBL: CHEMBL4722] [GtoPdb: 1936] [UniProtKB: O14965] There should be some charts here, you may need to enable JavaScript!
aurora kinase B/Serine/threonine-protein kinase Aurora-B in Human [ChEMBL: CHEMBL2185] [GtoPdb: 1937] [UniProtKB: Q96GD4] There should be some charts here, you may need to enable JavaScript!
aurora kinase C/Serine/threonine-protein kinase Aurora-C in Human [ChEMBL: CHEMBL3935] [GtoPdb: 1938] [UniProtKB: Q9UQB9] There should be some charts here, you may need to enable JavaScript!
serum/glucocorticoid regulated kinase 1/Serine/threonine-protein kinase Sgk1 in Human [ChEMBL: CHEMBL2343] [GtoPdb: 1534] [UniProtKB: O00141] There should be some charts here, you may need to enable JavaScript!
TRAF2 and NCK interacting kinase/TRAF2- and NCK-interacting kinase in Human [ChEMBL: CHEMBL4527] [GtoPdb: 2244] [UniProtKB: Q9UKE5] There should be some charts here, you may need to enable JavaScript!
ABL proto-oncogene 1, non-receptor tyrosine kinase/Tyrosine-protein kinase ABL in Human [ChEMBL: CHEMBL1862] [GtoPdb: 1923] [UniProtKB: P00519] There should be some charts here, you may need to enable JavaScript!
LCK proto-oncogene, Src family tyrosine kinase/Tyrosine-protein kinase LCK in Human [ChEMBL: CHEMBL258] [GtoPdb: 2053] [UniProtKB: P06239] There should be some charts here, you may need to enable JavaScript!
fms related receptor tyrosine kinase 3/Tyrosine-protein kinase receptor FLT3 in Human [ChEMBL: CHEMBL1974] [GtoPdb: 1807] [UniProtKB: P36888] There should be some charts here, you may need to enable JavaScript!
SRC proto-oncogene, non-receptor tyrosine kinase/Tyrosine-protein kinase SRC in Human [ChEMBL: CHEMBL267] [GtoPdb: 2206] [UniProtKB: P12931] There should be some charts here, you may need to enable JavaScript!
spleen associated tyrosine kinase/Tyrosine-protein kinase SYK in Human [ChEMBL: CHEMBL2599] [GtoPdb: 2230] [UniProtKB: P43405] There should be some charts here, you may need to enable JavaScript!
zeta chain of T cell receptor associated protein kinase 70/Tyrosine-protein kinase ZAP-70 in Human [ChEMBL: CHEMBL2803] [GtoPdb: 2285] [UniProtKB: P43403] There should be some charts here, you may need to enable JavaScript!
fms related receptor tyrosine kinase 1/Vascular endothelial growth factor receptor 1 in Human [ChEMBL: CHEMBL1868] [GtoPdb: 1812] [UniProtKB: P17948] There should be some charts here, you may need to enable JavaScript!
death associated protein kinase 3 in Human [GtoPdb: 2004] [UniProtKB: O43293] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
protein kinase AMP-activated non-catalytic subunit beta 2/protein kinase AMP-activated non-catalytic subunit gamma 1/protein kinase AMP-activated catalytic subunit alpha 2/protein kinase AMP-activated catalytic subunit alpha 1/protein kinase AMP-activated non-catalytic subunit gamma 3/protein kinase AMP-activated non-catalytic subunit gamma 2/protein kinase AMP-activated non-catalytic subunit beta 1/AMP-activated protein kinase, AMPK in Human (target type: PROTEIN COMPLEX GROUP) [ChEMBL: CHEMBL2096907] [GtoPdb: 1544, 1545, 1542, 1541, 1547, 1546, 1543] [UniProtKB: O43741, P54619, P54646, Q13131, Q9UGI9, Q9UGJ0, Q9Y478]
ChEMBL	Inhibition of wild type human AMPK by high throughput ATP-[33P] radiolabeled assay	B	5.82	pIC50	1512	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
mitogen-activated protein kinase 8/c-Jun N-terminal kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2276] [GtoPdb: 1496] [UniProtKB: P45983]
ChEMBL	Inhibition of wild type human wild type JNK1 by qPCR analysis	B	5.48	pIC50	3280	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
ChEMBL	Inhibition of wild type human JNK1 by high throughput [33P]-ATP radiolabeled assay	B	5.49	pIC50	3200	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
cyclin dependent kinase 1/Cyclin-dependent kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL308] [GtoPdb: 1961] [UniProtKB: P06493]
ChEMBL	Inhibition of wild type human CDK1 by high throughput ATP-[33P] radiolabeled assay	B	5.95	pIC50	1125	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
cyclin dependent kinase 2/Cyclin-dependent kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL301] [GtoPdb: 1973] [UniProtKB: P24941]
ChEMBL	Inhibition of wild type human CDK2 by high throughput ATP-[33P] radiolabeled assay	B	5.93	pIC50	1180	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
glycogen synthase kinase 3 beta/Glycogen synthase kinase-3 beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL262] [GtoPdb: 2030] [UniProtKB: P49841]
ChEMBL	Inhibition of wild type human GSK3B by high throughput ATP-[33P] radiolabeled assay	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
MET proto-oncogene, receptor tyrosine kinase/Hepatocyte growth factor receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3717] [GtoPdb: 1815] [UniProtKB: P08581]
ChEMBL	Inhibition of wild type human c-MET by high throughput ATP-[33P] radiolabeled assay	B	6.75	pIC50	177	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
Kv11.1/HERG in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL240] [GtoPdb: 572] [UniProtKB: Q12809]
ChEMBL	Inhibition of human ERG tail current transfected in HEK293 cells by patch clamp assay	B	4.68	pIC50	21000	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
component of inhibitor of nuclear factor kappa B kinase complex/Inhibitor of nuclear factor kappa B kinase alpha subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3476] [GtoPdb: 1989] [UniProtKB: O15111]
ChEMBL	Inhibition of wild type human IKKa by high throughput ATP-[33P] radiolabeled assay	B	6.23	pIC50	591	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
inhibitor of nuclear factor kappa B kinase subunit beta/Inhibitor of nuclear factor kappa B kinase beta subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1991] [GtoPdb: 2039] [UniProtKB: O14920]
ChEMBL	Inhibition of wild type human IKKb by high throughput ATP-[33P] radiolabeled assay	B	6.59	pIC50	257	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
Insulin-like growth factor I receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1957] [GtoPdb: 1801] [UniProtKB: P08069]
ChEMBL	Inhibition of wild type human IGF1R by high throughput ATP-[33P] radiolabeled assay	B	6.51	pIC50	307	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
Insulin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1981] [GtoPdb: 1800] [UniProtKB: P06213]
ChEMBL	Inhibition of wild type human IR by high throughput ATP-[33P] radiolabeled assay	B	6.7	pIC50	200	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
leucine rich repeat kinase 2/Leucine-rich repeat serine/threonine-protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075104] [GtoPdb: 2059] [UniProtKB: Q5S007]
ChEMBL	Inhibition of human wild type LRRK2 by qPCR analysis	B	7.96	pIC50	11	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
GtoPdb	-	-	7.96	pIC50	11	nM	IC50	J Med Chem (2013) 56: 8032-48 [PMID:24044867]
mitogen-activated protein kinase 1/MAP kinase ERK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4040] [GtoPdb: 1495] [UniProtKB: P28482]
ChEMBL	Inhibition of wild type human ERK2 by high throughput ATP-[33P] radiolabeled assay	B	5.2	pIC50	6290	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
mitogen-activated protein kinase 14/MAP kinase p38 alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL260] [GtoPdb: 1499] [UniProtKB: Q16539]
ChEMBL	Inhibition of wild type human P38a by high throughput ATP-[33P] radiolabeled assay	B	4.92	pIC50	12050	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
mitogen-activated protein kinase kinase kinase 10/Mitogen-activated protein kinase kinase kinase 10 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2873] [GtoPdb: 2070] [UniProtKB: Q02779]
ChEMBL	Inhibition of MLK2 (unknown origin)	B	7.38	pIC50	42	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
GtoPdb	-	-	7.38	pIC50	42	nM	IC50	J Med Chem (2013) 56: 8032-48 [PMID:24044867]
mitogen-activated protein kinase kinase kinase 11/Mitogen-activated protein kinase kinase kinase 11 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2708] [GtoPdb: 2071] [UniProtKB: Q16584]
GtoPdb	-	-	7.85	pIC50	14	nM	IC50	J Med Chem (2013) 56: 8032-48 [PMID:24044867]
ChEMBL	Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATP	B	7.85	pIC50	14	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
mitogen-activated protein kinase kinase kinase 11/Mitogen-activated protein kinase kinase kinase 11 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2434817] [GtoPdb: 2071] [UniProtKB: Q80XI6]
ChEMBL	Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISA	B	6.34	pIC50	460	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
mitogen-activated protein kinase kinase kinase 2/Mitogen-activated protein kinase kinase kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5914] [GtoPdb: 2077] [UniProtKB: Q9Y2U5]
ChEMBL	Inhibition of wild type human MEKK2 by high throughput ATP-[33P] radiolabeled assay	B	6.18	pIC50	661	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
GtoPdb	-	-	6.18	pIC50	661	nM	IC50	J Med Chem (2013) 56: 8032-48 [PMID:24044867]
mitogen-activated protein kinase kinase kinase 9/Mitogen-activated protein kinase kinase kinase 9 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2872] [GtoPdb: 2084] [UniProtKB: P80192]
GtoPdb	-	-	7.72	pIC50	19	nM	IC50	J Med Chem (2013) 56: 8032-48 [PMID:24044867]
ChEMBL	Inhibition of MLK1 (unknown origin)	B	7.72	pIC50	19	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
neurotrophic receptor tyrosine kinase 1/Nerve growth factor receptor Trk-A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2815] [GtoPdb: 1817] [UniProtKB: P04629]
ChEMBL	Inhibition of wild type human TRKA by high throughput ATP-[33P] radiolabeled assay	B	7.07	pIC50	85	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
neurotrophic receptor tyrosine kinase 2/Neurotrophic tyrosine kinase receptor type 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4898] [GtoPdb: 1818] [UniProtKB: Q16620]
ChEMBL	Inhibition of wild type human TRKB by high throughput ATP-[33P] radiolabeled assay	B	6.66	pIC50	217	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
Protein delta homolog 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5671] [UniProtKB: P80370]
ChEMBL	Binding affinity to human wild type DLK by qPCR analysis	B	7.15	pKd	70	nM	Kd	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
ChEMBL	Inhibition of human wild type DLK by qPCR analysis	B	6.82	pIC50	150	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
Rho associated coiled-coil containing protein kinase 1/Rho-associated protein kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3231] [GtoPdb: 1503] [UniProtKB: Q13464]
ChEMBL	Inhibition of wild type human ROCK1 by high throughput ATP-[33P] radiolabeled assay	B	5.99	pIC50	1030	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
Rho associated coiled-coil containing protein kinase 2/Rho-associated protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2973] [GtoPdb: 1504] [UniProtKB: O75116]
ChEMBL	Inhibition of wild type human ROCK2 by high throughput ATP-[33P] radiolabeled assay	B	6.95	pIC50	111	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
aurora kinase A/Serine/threonine-protein kinase Aurora-A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4722] [GtoPdb: 1936] [UniProtKB: O14965]
ChEMBL	Inhibition of wild type human Aurora kinase A by high throughput ATP-[33P] radiolabeled assay	B	6.97	pIC50	108	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
aurora kinase B/Serine/threonine-protein kinase Aurora-B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2185] [GtoPdb: 1937] [UniProtKB: Q96GD4]
ChEMBL	Inhibition of wild type human Aurora kinase B by high throughput ATP-[33P] radiolabeled assay	B	6.91	pIC50	123	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
aurora kinase C/Serine/threonine-protein kinase Aurora-C in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3935] [GtoPdb: 1938] [UniProtKB: Q9UQB9]
ChEMBL	Inhibition of wild type human Aurora kinase C kinase by high throughput ATP-[33P] radiolabeled assay	B	6.54	pIC50	290	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
serum/glucocorticoid regulated kinase 1/Serine/threonine-protein kinase Sgk1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2343] [GtoPdb: 1534] [UniProtKB: O00141]
ChEMBL	Inhibition of wild type human SGK1 by high throughput ATP-[33P] radiolabeled assay	B	6.7	pIC50	201	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
TRAF2 and NCK interacting kinase/TRAF2- and NCK-interacting kinase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4527] [GtoPdb: 2244] [UniProtKB: Q9UKE5]
ChEMBL	Inhibition of TNIK (unknown origin)	B	8.28	pIC50	5.2	nM	IC50	Bioorg Med Chem Lett (2021) 33: 127749-127749 [PMID:33340663]
ABL proto-oncogene 1, non-receptor tyrosine kinase/Tyrosine-protein kinase ABL in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1862] [GtoPdb: 1923] [UniProtKB: P00519]
ChEMBL	Inhibition of wild type human ABL1 by high throughput ATP-[33P] radiolabeled assay	B	8.17	pIC50	6.8	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
ChEMBL	Inhibition of wild type human ABL1 T315I mutant by high throughput ATP-[33P] radiolabeled assay	B	8.52	pIC50	3	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
LCK proto-oncogene, Src family tyrosine kinase/Tyrosine-protein kinase LCK in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL258] [GtoPdb: 2053] [UniProtKB: P06239]
ChEMBL	Inhibition of wild type human LCK by high throughput ATP-[33P] radiolabeled assay	B	6.48	pIC50	333	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
fms related receptor tyrosine kinase 3/Tyrosine-protein kinase receptor FLT3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1974] [GtoPdb: 1807] [UniProtKB: P36888]
ChEMBL	Inhibition of FLT3-L-stimulated wild type full length human FLT3 autophosphorylation expressed in MEF preincubated for 90 mins followed by FLT3-L stimulation measured after 5 mins by ELISA	B	6.25	pIC50	560	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
ChEMBL	Inhibition of wild type human FLT3 by high throughput ATP-[33P] radiolabeled assay	B	8.4	pIC50	4	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
GtoPdb	-	-	8.4	pIC50	4	nM	IC50	J Med Chem (2013) 56: 8032-48 [PMID:24044867]
SRC proto-oncogene, non-receptor tyrosine kinase/Tyrosine-protein kinase SRC in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL267] [GtoPdb: 2206] [UniProtKB: P12931]
ChEMBL	Inhibition of wild type human SRC by high throughput ATP-[33P] radiolabeled assay	B	5.36	pIC50	4330	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
spleen associated tyrosine kinase/Tyrosine-protein kinase SYK in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2599] [GtoPdb: 2230] [UniProtKB: P43405]
ChEMBL	Inhibition of wild type human SYK by high throughput ATP-[33P] radiolabeled assay	B	6.14	pIC50	731	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
zeta chain of T cell receptor associated protein kinase 70/Tyrosine-protein kinase ZAP-70 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2803] [GtoPdb: 2285] [UniProtKB: P43403]
ChEMBL	Inhibition of wild type human ZAP70 by high throughput ATP-[33P] radiolabeled assay	B	5.3	pIC50	5050	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
fms related receptor tyrosine kinase 1/Vascular endothelial growth factor receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1868] [GtoPdb: 1812] [UniProtKB: P17948]
ChEMBL	Inhibition of wild type human FLT1 by high throughput ATP-[33P] radiolabeled assay	B	7.41	pIC50	39	nM	IC50	J Med Chem (2013) 56: 8032-8048 [PMID:24044867]
death associated protein kinase 3 in Human [GtoPdb: 2004] [UniProtKB: O43293]
GtoPdb	-	-	6.82	pIC50	150	nM	IC50	J Med Chem (2013) 56: 8032-48 [PMID:24044867]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]