CCL5 [Ligand Id: 758] activity data from GtoPdb

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  • CCR1 in Human [GtoPdb: 58] [UniProtKB: P32246]
Created with Highcharts 10.3.3ValuesChart context menuCCR1pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • CCR3 in Human [GtoPdb: 60] [UniProtKB: P51677]
Created with Highcharts 10.3.3ValuesChart context menuCCR3pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • CCR5 in Human [GtoPdb: 62] [UniProtKB: P51681]
Created with Highcharts 10.3.3ValuesChart context menuCCR5pKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
  • CXCR3 in Human [GtoPdb: 70] [UniProtKB: P49682]
Created with Highcharts 10.3.3ValuesChart context menuCXCR3pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • GPR75 in Human [GtoPdb: 115] [UniProtKB: O95800]
Created with Highcharts 10.3.3ValuesChart context menuGPR75pKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CCR1 in Human [GtoPdb: 58] [UniProtKB: P32246]
GtoPdb - - 8.2 pKi - - - J Biol Chem (1998) 273: 15687-92 [PMID:9624164];
J Biol Chem (1995) 270: 29671-29675 [PMID:8530354]
CCR3 in Human [GtoPdb: 60] [UniProtKB: P51677]
GtoPdb - - 9.3 pKi - - - J Exp Med (1996) 183: 2349-54 [PMID:8642344]
CCR5 in Human [GtoPdb: 62] [UniProtKB: P51681]
GtoPdb - - 9.7 pKi - - - Proc Natl Acad Sci USA (1999) 96: 5698-703 [PMID:10318947];
Biochem Pharmacol (2005) 71: 163-72 [PMID:16298345];
Cell Immunol (1998) 189: 160-8 [PMID:9790730]
CXCR3 in Human [GtoPdb: 70] [UniProtKB: P49682]
GtoPdb - - 6.4 pKi - - - J Biol Chem (1998) 273: 18288-91 [PMID:9660793]
GPR75 in Human [GtoPdb: 115] [UniProtKB: O95800]
GtoPdb - - 9.59 pEC50 0.26 nM EC50 Br J Pharmacol (2006) 149: 490-7 [PMID:17001303]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.