The IUPHAR Guide to IMMUNOPHARMACOLOGY ligand list

GtoImmuPdb antibodies only: Includes therapeutic monoclonal antibodies.

A  B  C  D  E  F  G  I  L  M  N  O  P  Q  R  S  T  U  V  X 

Ligand name ID Synonyms
A Back to top
abatacept 6891 BMS-188667, CTLA4-IgG4m, Orencia®, RG-1046, RG-2077
adalimumab 4860 D2E7, FKB327, Humira®
alefacept 6787 Amevive®, BG 9273, BG 9712, BG-9273, BG-9712, Lfa3Tip
alemtuzumab 6770 campath 1H, Campath®, campath-1H, Lemtrada®
AMG820 9106
andecaliximab 9510 GS-5745
anifrolumab 8258 MDX-1333, MEDI-546
atezolizumab 7990 MPDL3280A, Tecentriq®
avelumab 8735 Bavencio®, MSB-0010718C, MSB0010718C
 
B Back to top
basiliximab 6879 CHI-621, L04AC02, SDZ-CHI-621, Simulect®
belatacept 6892 BMS-224818, LEA29Y, Nulojix®
belimumab 6887 Benlysta®, hBlySmAb-1.1, lymphostat-B
benralizumab 7674 BIW-8405, KHK4563, MEDI-563
BGB-A317 9592
bimekizumab 9411 CA028_0496, CDP4940, gL7gH9, UCB-4940, UCB4940, Zu-G1
blinatumomab 7384 Blincyto®, bscCD19xCD3, MEDI-538, MT-103, MT103
BMS-986016 9536
brazikumab 9293 AMG 139, AMG-139, MEDI2070
brentuximab vedotin 6772 Adcetris®, anti-CD30 ADC SGN-35, SGN 35
briakinumab 9213 ABT-874, J-695, J695, Ozespa
brodalumab 7540 AMG-827, AMG827, Lumicef®, Siliq®
 
C Back to top
cabiralizumab 9107 BMS-986227, FPA-008, FPA008
canakinumab 6773 ACZ 885, ACZ885, Ilaris®
certolizumab pegol 6774 CDP870, Cimzia®, PHA 738144
clazakizumab 9195 ALD-518, ALD518, BMS-945429
 
D Back to top
daclizumab 6880 L04AC01, RO-24-7375, Ro-247375, Zenapax®
daratumumab 7395 3003-005, Darzalex®, HuMax-CD38, JNJ-54767414
dectrekumab 8714 QAX-576, QAX576
dupilumab 7574 Dupixent®, REGN668, SAR231893
durvalumab 7985 anti-B7H1 monoclonal antibody, Imfinzi®, MEDI-4736, MEDI4736
 
E Back to top
eculizumab 6884 h5G1.1, h5G1.1VHC, Soliris®
efalizumab 6593 anti alphaL integrin, antiCD11 alpha, hu1124, Raptiva®
eldelumab 9047 BMS-936557, MDX-1100
elezanumab 9290 ABT-555, AE12-1Y-QL
elotuzumab 8361 BMS-901608, Empliciti®, HuLuc63
emactuzumab 8944 RG7155, RO5509554
emapalumab 9295 Ni-0501, NI-0501
enoblituzumab 9589 MGA-271, MGA271
enokizumab 8934 7F3com-2H2, MEDI-528, MEDI528
epratuzumab 8088 90Y-DOTA-hLL2, 90Y-epratuzumab tetraxetan, 90Y-hLL2, AMG-412, IMMU-hLL2, LymphoCide® (proposed proprietary name)
etanercept 6789 Enbrel®, Rhu Tnfr:Fc, TNFR-Fc, TNR 001
etrolizumab 8407 PRO145223, RG-7413, RG7413, rhuMAb Beta7
 
F Back to top
fezakinumab 9281 ILV-094
 
G Back to top
galcanezumab 8967 clone III, LY-2951742, LY2951742
gemtuzumab ozogamicin 6775 CDP 771, CMA 676, hP67.6-calicheamicin, Mylotarg®, WAY-CMA 676
gevokizumab 7394 Xoma 052, XOMA-052
golimumab 6776 CNTO-148, CNTO148, Simponi®
GSK3050002 9623 E6071, KANAb071
guselkumab 7998 CNTO-1959, Tremfya®
 
I Back to top
ibritumomab tiuxetan 6777 IDEC-2B8, IDEC-Y2B8-yttrium ibritumomab tiuxetan, NSC-715848, Zevalin®
IMCgp100 7378
infliximab 5004 cA2, Inflectra®, Remicade®, Remsima®, SB2, TA-650
inotuzumab ozogamicin 8266 Besponsa®, CMC-544
ipilimumab 6888 MDX-010, MDX-101, MDX-CTLA-4, Yervoy®
itolizumab 9421 Alzumab®, T1h
ixekizumab 7541 LY-2439821, Taltz®
 
L Back to top
lebrikizumab 7684 MILR1444A, RG3637, TNX-650
lenzilumab 8935 KB-003, KB003
ligelizumab 8997 CL-2C, NVP-QGE031, QGE031
lintuzumab 7983 ACTIMAB®, HuM195, SGN-33, SMART M195
lirilumab 9310 1-7F9, BMS-986015, IPH2102
lulizumab pegol 8460 BMS-931699, BMS931699
lutikizumab 9297 ABT-981, E26.13-SS-X3
LY3022855 9109 IMC-CS4
 
M Back to top
mavrilimumab 7785 CAM-3001
MCS110 9110
mepolizumab 7685 Nucala®, SB-240563
milatuzumab 8267 hLL1, IMMU-115
mogamulizumab 6477 KW-0761, Poteligeo®
monalizumab 8323 humZ270, IPH-2201, NN8765-3658
MORAb-022 9624 gimsilumab (proposed INN)
moxetumomab pasudotox 7675 CAT-8015, GCR-8015, HA22
muromonab-CD3 6889 L04AA02, OKT-3, Orthoclone Okt3®
 
N Back to top
natalizumab 6591 AN100226, anti-alpha4 integrin, anti-VLA4, Tysabri®
nemolizumab 8720 CIM 331, CIM331
nivolumab 7335 BMS-936558, MDX-1106, ONO-4538, Opdivo®
 
O Back to top
obinutuzumab 6941 GA-101, GA101, Gazyva®
ocrelizumab 7580 2H7, Ocrevus®, PRO70769, RG1594
ofatumumab 6778 Arzerra®, GSK 1841157, GSK1841157, humax-CD20
oleclumab 9596 MEDI 9447, MEDI-9447
omalizumab 6890 IGE25, olizumab, R03DX05, RG-3648, rhumab-E25, Xolair®
OPN305 9408 OPN-305, VK5A/H4
OSE-127 9604 Effi-7
ozoralizumab 9638 ATN-103, PF-5230896
 
P Back to top
pascolizumab 7786 SB-240683
pembrolizumab 7499 Keytruda®, lambrolizumab, MK-3475
PF-00547659 9340 PF-547659, SHP647
plozalizumab 8921 hu1D9, MLN-1202, MLN1202
 
Q Back to top
quilizumab 8998 47H4 v5 hulgG1, MEMP1972A, RG-7449
 
R Back to top
remtolumab 9597 A-1230717, ABT-122
reslizumab 8091 CDP-835, CDP835, Cinqair®, JES1-39D10, SCH55700
rilonacept 6790 Arcalyst®, IL-1 Trap, interleukin-1 Trap
risankizumab 8922 BI 655066, BI-655066
rituximab 6780 HSDB 7455, MabThera®, Rituxan®
rontalizumab 9640 9F3v13, RhuMAB IFNalpha, rhuMAb interferon-α
rovelizumab 9598 Hu23F2G, LeukArrest
 
S Back to top
sapelizumab 9093 SA-237, SA237
sarilumab 7999 Kevzara®, REGN88, SAR153191
secukinumab 8078 AIN 457, AIN457, Cosentyx®, NVP-AIN457
sifalimumab 8257 MDX-1103, MEDI-545, MEDI545
siltuximab 7396 cLLB8, CNTO 328, Sylvant®
sirukumab 7989 CNTO 136, CNTO-136, Plivensia (proposed trade name)
 
T Back to top
tabalumab 8000 LY 2127399, LY2127399
tezepelumab 8933 AMG 157, AMG-157, MEDI-9929, MEDI9929
tildrakizumab 8093 MK-3222, MK3222, SCH-900222, SCH900222
timolumab 9097 8c10, BTT-1023, BTT1023, r8c10, SI-3106, SI-636
tocilizumab 6881 Actemra®, R-1569, RG-1569, RHPM-1, RoActemra®
tositumomab 6781 Bexxar®, V10XA53
tralokinumab 8001 BAK1.1, CAT-354
tremelimumab 8462 CP-675, CP-675,206, CP-675206, ticilimumab
 
U Back to top
ublituximab 8920 LFB-R603, TG-1101, TGTX-1101
ulocuplumab 9161 BMS-936564, MDX-1338
urelumab 9311 BMS 663513, BMS-663513
ustekinumab 6885 CNTO-1275, L04AC05, Stelara®, TT-20
utomilumab 9244 PF-05082566
 
V Back to top
vadastuximab talirine 9434 SGN-CD33A
vedolizumab 7437 Entyvio®, LDP-02, LDP02, MLN-0002, MLN-002, MLN002
veltuzumab 8268 hA20, IMMU-106
vobarilizumab 8363 ALX-0061
vunakizumab 9296 SHR-1314
 
X Back to top
Xilonix TN 8528