toripalimab [Ligand Id: 12989] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| programmed cell death 1 (CD279) in Monkey [GtoPdb: 2760] | ||||||||
| GtoPdb | Binding affinity for PD-1 on cynomolgus monkey CD8+ T cells | - | 8.92 | pKi | 1.2 | nM | Ki | Acta Pharmacol Sin (2017) 38: 710-718 [PMID:28317872] |
| programmed cell death 1 (CD279) in Human [GtoPdb: 2760] [UniProtKB: Q15116] | ||||||||
| GtoPdb | Binding affinity for PD-1 on human CD8+ T cells | - | 8.68 | pKd | 2.1 | nM | Kd | Acta Pharmacol Sin (2017) 38: 710-718 [PMID:28317872] |
| GtoPdb | Measuring displacement of biotin-PD-L1 from 293F cells expressing hPD-1 | - | 7.68 | pEC50 | 21 | nM | EC50 | Acta Pharmacol Sin (2017) 38: 710-718 [PMID:28317872] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
