GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.
romiplostim 
GtoPdb Ligand ID: 6974
|
Synonyms: MG531 | Nplate®
romiplostim is an approved drug (FDA (2008), EMA (2009))
Compound class:
Peptide
Comment: This drug is a thrombopoietin receptor agonist, although its peptide sequence does not resemble that of the endogenous peptide thrombopoietin. Romiplostim is known as a peptibody, a fusion between the Fc portion of immunoglobulin and a therapeutic peptide. In this case the drug exists as a heterodimer. The carboxy terminal 14 amino acid residues of this peptibody constitute the thrombopoietin receptor binding domain (single letter amino acid code: IEGPTLRQWLAARA).
|
For advanced searching click here to open chemical structure editor
Other Similar Sequences  |
|
| rilonacept |
Targetsnull |
| abatacept |
TargetsCD80; CD86 |
| belatacept |
TargetsCD80; CD86 |
| trebananib |
Targetsnull |
| resokine | |
| efgartigimod alfa |
TargetsFc fragment of IgG receptor and transporter |
| luspatercept |
Targetsnull |
| MK-7110 |
Targetssialic acid binding Ig like lectin 10 |
| inbakicept | |
| sotatercept |
Targetsnull |
| efzofitimod | |
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License