inbakicept   Click here for help

GtoPdb Ligand ID: 11593

Synonyms: 15RalphaSu-Fc
Compound class: Antibody
Comment: Inbakicept is a fusion protein that links the Sushi domain of the IL15 receptor α subunit (amino acids 1-65 of the peptide sequence provided here) with a human IgG1 Fc domain (aa 81-190 Fc CH2 domain, aa 191-297 Fc CH3 domain). It is one of the protein components of the clinical stage IL-15 superagonist complex ALT-803 [1-2]. It forms a dimeric structure that binds nogapendekin alfa.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
11029 inbakicept
Synonyms Click here for help
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 926
Other databases
GtoPdb PubChem SID 442878627
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