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inbakicept 
GtoPdb Ligand ID: 11593
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Synonyms: 15RalphaSu-Fc
Compound class:
Peptide
Comment: Inbakicept is a fusion protein that links the Sushi domain of the IL15 receptor α subunit (amino acids 1-65 of the peptide sequence provided here) with a human IgG1 Fc domain (aa 81-190 Fc CH2 domain, aa 191-297 Fc CH3 domain). It is one of the protein components of the clinical stage IL-15 superagonist complex ALT-803 [1-2]. It forms a dimeric structure that binds nogapendekin alfa.
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Other Similar Sequences  |
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| rilonacept |
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TargetsCD80; CD86 |
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TargetsCD80; CD86 |
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| resokine | |
| efgartigimod alfa |
TargetsFc fragment of IgG receptor and transporter |
| luspatercept |
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| MK-7110 |
Targetssialic acid binding Ig like lectin 10 |
| sotatercept |
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| efzofitimod | |
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