nogapendekin alfa 
GtoPdb Ligand ID: 11594
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Synonyms: IL15 D72
Compound class:
Peptide or derivative
Comment: Inogapendekin alfa is recombinant human IL-15 with an amino acid substitution (Asn72Asp/N72D) that enhances its agonist activity at the IL-15Rβγc complex. IL-15N72D increases biological activity by 4-5-fold compared to the wild type cytokine. Inogapendekin alfa is synthesised in tandem with inbakicept to generate the clinical stage IL-15 superagonist complex ALT-803.
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Classification  |
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| Compound class | Peptide or derivative |
| International Nonproprietary Names |
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| INN number | INN |
| 11157 | nogapendekin alfa |
| Synonyms |
| IL15 D72 |
| Database Links |
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| Specialist databases | |
| IMGT/mAb-DB | 983 |
| Other databases | |
| GtoPdb PubChem SID | 442878628 |
| Search PubMed clinical trials | nogapendekin alfa |
| Search PubMed titles | nogapendekin alfa |
| Search PubMed titles/abstracts | nogapendekin alfa |
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