Compound class:
Synthetic organic
Comment: Inhibitor 1 inhibits the ORAI1 protein component of the CRAC channel [1]. The chemical structure represents a novel ORAI1-specific chemotype that is suitable for the development of more refined CRAC channel inhibitors.
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Immunopharmacology Comments |
Inhibitor 1 inhibits IL-2 production in Jurkat cells [1].. |