elotuzumab   Click here for help

GtoPdb Ligand ID: 8361

Synonyms: BMS-901608 | Empliciti® | HuLuc63
Approved drug Immunopharmacology Ligand
elotuzumab is an approved drug (FDA (2015), EMA (2016))
Compound class: Antibody
Comment: Elotuzumab is a humanized IgG1 antibody targeting CS1 (SLAMF7) [1-2].
Peptide sequences for elotuzumab are available from its IMGT/mAb-DB record.
Click here for help
Bioactivity Comments
The biological activity of elotuzumab has been well characterised [1-2]. We have tagged the primary molecular target, providing data from patent US7709610 [5].
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CS1 (CD319) Primary target of this compound Hs Antibody Binding 8.1 pKd - 5
pKd 8.1 (Kd 8.86x10-9 M) [5]