Abbreviated name: TNF membrane form
Synonyms: cachectin | necrosin | TNFα
Compound class:
Endogenous peptide in human, mouse or rat
Comment: TNFα is a pro-inflammatory, acute phase cytokine involved in systemic inflammation.
The TNFSF2 precursor is also cleaved into a membrane-bound form of the ligand.
Species: Human
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Selected 3D Structures | ||
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Post-translational Modification | |
Predicted phosphorylation of serine residue at position 2; residues 19 and 20 are N6-myristoyl lysine |