urotensin-II   Click here for help

GtoPdb Ligand ID: 2153

Abbreviated name: U-II
Species: Human
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References
1. Ames RS, Sarau HM, Chambers JK, Willette RN, Aiyar NV, Romanic AM, Louden CS, Foley JJ, Sauermelch CF, Coatney RW et al.. (1999)
Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14.
Nature, 401 (6750): 282-6. [PMID:10499587]
2. Douglas SA, Behm DJ, Aiyar NV, Naselsky D, Disa J, Brooks DP, Ohlstein EH, Gleason JG, Sarau HM, Foley JJ et al.. (2005)
Nonpeptidic urotensin-II receptor antagonists I: in vitro pharmacological characterization of SB-706375.
Br J Pharmacol, 145 (5): 620-35. [PMID:15852036]
3. Elshourbagy NA, Douglas SA, Shabon U, Harrison S, Duddy G, Sechler JL, Ao Z, Maleeff BE, Naselsky D, Disa J et al.. (2002)
Molecular and pharmacological characterization of genes encoding urotensin-II peptides and their cognate G-protein-coupled receptors from the mouse and monkey.
Br J Pharmacol, 136 (1): 9-22. [PMID:11976263]
4. Liu Q, Pong SS, Zeng Z, Zhang Q, Howard AD, Williams Jr DL, Davidoff M, Wang R, Austin CP, McDonald TP et al.. (1999)
Identification of urotensin II as the endogenous ligand for the orphan G-protein-coupled receptor GPR14.
Biochem Biophys Res Commun, 266 (1): 174-8. [PMID:10581185]
5. Mori M, Sugo T, Abe M, Shimomura Y, Kurihara M, Kitada C, Kikuchi K, Shintani Y, Kurokawa T, Onda H et al.. (1999)
Urotensin II is the endogenous ligand of a G-protein-coupled orphan receptor, SENR (GPR14).
Biochem Biophys Res Commun, 265 (1): 123-9. [PMID:10548501]
6. Nothacker HP, Wang Z, McNeill AM, Saito Y, Merten S, O'Dowd B, Duckles SP, Civelli O. (1999)
Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction.
Nat Cell Biol, 1 (6): 383-5. [PMID:10559967]