[33P]relaxin (human)   Click here for help

GtoPdb Ligand ID: 1991

Synonyms: [33P]H2 relaxin (human) | [33P]Human gene 2 relaxin
 Ligand is labelled  Ligand is radioactive
Compound class: Peptide or derivative
Comment: Radiolabelled form of recombinant human H2 relaxin. H2 relaxin consists of 2 subunits, an A chain and a B chain. The relaxin entry provides subunit peptide sequence information. The literature does not specify which of the subunits is labelled with 33P
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Halls ML, Bond CP, Sudo S, Kumagai J, Ferraro T, Layfield S, Bathgate RA, Summers RJ. (2005)
Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8).
J Pharmacol Exp Ther, 313 (2): 677-87. [PMID:15649866]
2. Sudo S, Kumagai J, Nishi S, Layfield S, Ferraro T, Bathgate RA, Hsueh AJ. (2003)
H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2.
J Biol Chem, 278 (10): 7855-62. [PMID:12506116]