Synonyms: 1,3-Dimethyl-2[(oxopropyl)thio]imidazolium [1]
Compound class:
Synthetic organic
Comment: R283 is an active site-directed inhibitor of intracellular transglutaminase activity.
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Immunopharmacology Comments |
R283 blocks the pro-inflammatory effect of transglutaminase up-regulation by amyloid β1-42 in human monocytes (THP-1 cells) [1]. |