Compound class:
Synthetic organic
Comment: Fluorescent MIF ligand B is reported in Cisneros et al. (2016) [1]. It is a macrophage migration inhibitory factor (MIF) inhibitor tethered to fluorescein to generate a probe suitable for fluorescence polarization assay determination of dissociation constant (Kd) of MIF inhibitors as an alternative to the Ki or IC50 values that are obtained from tautomerization assays.
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Selectivity at ligand targets | ||||||||||||||||||||||||||||||||||
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