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Quaternary Structure: Complexes |
Interleukin-2 receptor |
Interleukin-4 receptor type I |
Interleukin-7 receptor |
Interleukin-9 receptor |
Interleukin-15 receptor |
Interleukin-21 receptor |
Gene and Protein Information | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | 1 | 369 | Xq13.1 | IL2RG | interleukin 2 receptor subunit gamma | |
Mouse | 1 | 369 | X 43.9 cM | Il2rg | interleukin 2 receptor, gamma chain | |
Rat | - | - | Xq31 | Il2rg | interleukin 2 receptor subunit gamma |
Previous and Unofficial Names |
CD132 | cytokine receptor common subunit gamma | IL-2RG | interleukin 2 receptor, gamma | interleukin 2 receptor, gamma chain | interleukin 2 receptor |
Database Links | |
Alphafold | P31785 (Hs), P34902 (Mm) |
CATH/Gene3D | 2.60.40.10 |
ChEMBL Target | CHEMBL4665588 (Hs), CHEMBL4665592 (Hs), CHEMBL2364167 (Hs) |
DrugBank Target | P31785 (Hs) |
Ensembl Gene | ENSG00000147168 (Hs), ENSMUSG00000031304 (Mm), ENSRNOG00000003954 (Rn) |
Entrez Gene | 3561 (Hs), 16186 (Mm), 140924 (Rn) |
Human Protein Atlas | ENSG00000147168 (Hs) |
KEGG Gene | hsa:3561 (Hs), mmu:16186 (Mm), rno:140924 (Rn) |
OMIM | 308380 (Hs) |
Pharos | P31785 (Hs) |
UniProtKB | P31785 (Hs), P34902 (Mm) |
Wikipedia | IL2RG (Hs) |
Immunopharmacology Comments |
IL2RG is a common signal transducing subunit shared by the receptors for several different cytokines, namely the IL-2 receptor heterotrimer, the IL-4 receptor type I, the IL-7 receptor, the IL-9 receptor, the IL-15 receptor and the IL-21 receptor. |
Immuno Process Associations | ||
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IL-2 receptor family: Interleukin-2 receptor subunit γ. Last modified on 10/04/2017. Accessed on 02/11/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=2303.