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Interleukin-2 receptor subunit γ

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Immunopharmacology Ligand  Target has curated data in GtoImmuPdb

Target id: 2303

Nomenclature: Interleukin-2 receptor subunit γ

Family: IL-2 receptor family

Quaternary Structure: Complexes
Interleukin-2 receptor
Interleukin-4 receptor type I
Interleukin-7 receptor
Interleukin-9 receptor
Interleukin-15 receptor
Interleukin-21 receptor
Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 369 Xq13.1 IL2RG interleukin 2 receptor subunit gamma
Mouse 1 369 X 43.9 cM Il2rg interleukin 2 receptor, gamma chain
Rat - - Xq31 Il2rg interleukin 2 receptor subunit gamma
Previous and Unofficial Names Click here for help
CD132 | cytokine receptor common subunit gamma | IL-2RG | interleukin 2 receptor, gamma | interleukin 2 receptor, gamma chain | interleukin 2 receptor
Database Links Click here for help
Alphafold
CATH/Gene3D
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Pharos
UniProtKB
Wikipedia
Immunopharmacology Comments
IL2RG is a common signal transducing subunit shared by the receptors for several different cytokines, namely the IL-2 receptor heterotrimer, the IL-4 receptor type I, the IL-7 receptor, the IL-9 receptor, the IL-15 receptor and the IL-21 receptor.
Immuno Process Associations
Immuno Process:  Cytokine production & signalling
Immuno Process:  Inflammation
Immuno Process:  B cell (activation)
Immuno Process:  Cellular signalling
Immuno Process:  Chemotaxis & migration
Immuno Process:  Immune regulation
Immuno Process:  Immune system development
Immuno Process:  T cell (activation)

How to cite this page

IL-2 receptor family: Interleukin-2 receptor subunit γ. Last modified on 10/04/2017. Accessed on 02/11/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=2303.