AL-78898A   Click here for help

GtoPdb Ligand ID: 9219

Synonyms: 4(1MeW) [2] | POT-4
Immunopharmacology Ligand
Comment: AL-78898A is an investigational analogue of compstatin [2], which acts as an irreversible inhibitor of complement component 3 (C3). C3 inhibitors are being actively investigated for clinical potential in inflammatory and degenerative diseases [1].
Peptide Sequence Click here for help
Chemical Modification
Acetylated amino terminal and amidated carboxy terminal. Cys2-Cys12 forms disulphide bond. Trp4 is methylated.