dectrekumab   Click here for help

GtoPdb Ligand ID: 8714

Synonyms: QAX-576 | QAX576
Immunopharmacology Ligand
Compound class: Antibody
Comment: Dectrekumab is a fully human investigational anti-interleukin 13 (IL-13) monoclonal antibody, with anti-inflammatory potential.
Peptide sequence and secondary structural information are available from dectrekumab's IMGT/mAb-DB record.
Peptide sequences for the heavy and light chains of dectrekumab match those provided in patent US8992916 B2 for clone 01951/G12 [1].
1. Campbell EM, Parveen S, Buechler J, Valkirs G. (2015)
Methods of using anti-IL13 human antibodies.
Patent number: US8992916 B2. Assignee: Novartis Ag.. Priority date: 21/10/2005. Publication date: 31/03/2015.
2. Rothenberg ME, Wen T, Greenberg A, Alpan O, Enav B, Hirano I, Nadeau K, Kaiser S, Peters T, Perez A et al.. (2015)
Intravenous anti-IL-13 mAb QAX576 for the treatment of eosinophilic esophagitis.
J Allergy Clin Immunol, 135 (2): 500-7. [PMID:25226850]