dectrekumab   Click here for help

GtoPdb Ligand ID: 8714

Synonyms: QAX-576 | QAX576
Immunopharmacology Ligand
Compound class: Antibody
Comment: Dectrekumab is a fully human investigational anti-interleukin 13 (IL-13) monoclonal antibody, with anti-inflammatory potential.
Peptide sequence and secondary structural information are available from dectrekumab's IMGT/mAb-DB record.
Peptide sequences for the heavy and light chains of dectrekumab match those provided in patent US8992916 B2 for clone 01951/G12 [1].
Immunopharmacology Disease
Disease X-Refs Comment References
Crohn's disease Disease Ontology: DOID:8778
OMIM: 266600
Orphanet: ORPHA206
 Phase 2 trial NCT01316601 in CD has been completed.
Asthma Disease Ontology: DOID:2841
OMIM: 600807
 Phase 2 trial NCT01479595 in asthma has been completed.
Allergic rhinitis Disease Ontology: DOID:4481
 Phase 2 trial NCT00584584 in allergic rhinitis has been completed.
Eosinophilic esophagitis Disease Ontology: DOID:13922
Orphanet: ORPHA73247
 Phase 2 trial NCT01022970 in eosinophilic esophagitis has been completed.