dectrekumab   Click here for help

GtoPdb Ligand ID: 8714

Synonyms: QAX-576 | QAX576
Immunopharmacology Ligand
Compound class: Antibody
Comment: Dectrekumab is a fully human investigational anti-interleukin 13 (IL-13) monoclonal antibody, with anti-inflammatory potential.
Peptide sequence and secondary structural information are available from dectrekumab's IMGT/mAb-DB record.
Peptide sequences for the heavy and light chains of dectrekumab match those provided in patent US8992916 B2 for clone 01951/G12 [1].
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
IL-13 Primary target of this compound Hs Antibody Binding 9.3 pKd - 1
pKd 9.3 (Kd 4.8x10-10 M) [1]