Synonyms: campath 1H | Campath® | campath-1H | Lemtrada®
alemtuzumab is an approved drug (FDA (2001), EMA (2013))
Compound class:
Antibody
Comment: CAMPATH-1 (CD52) antigen inhibitor. Functionally, alemtuzumab causes depletion and then recovery of the immune system.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record. View more information in the IUPHAR Pharmacology Education Project: alemtuzumab |
Immunopharmacology Disease | |||
Disease | X-Refs | Comment | References |
Relapsing-remitting multiple sclerosis |
Disease Ontology:
DOID:2378 |
Approved drug for RR-MS, and controlled access for B-cell chronic lymphocytic leukemia (CLL) and transplant indications. |