ChEMBL ligand: CHEMBL2426364
α2C-adrenoceptor/Alpha-2C adrenergic receptor in Human [ChEMBL: CHEMBL1916] [GtoPdb: 27] [UniProtKB: P18825] There should be some charts here, you may need to enable JavaScript!
Chromobox protein homolog 7 in Human [ChEMBL: CHEMBL1764946] [UniProtKB: O95931] There should be some charts here, you may need to enable JavaScript!
E3 ubiquitin-protein ligase UHRF1 in Human [ChEMBL: CHEMBL2424510] [UniProtKB: Q96T88] There should be some charts here, you may need to enable JavaScript!
κ receptor/Kappa-type opioid receptor in Human [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145] There should be some charts here, you may need to enable JavaScript!
Lethal(3)malignant brain tumor-like protein 1 in Human [ChEMBL: CHEMBL1287622] [UniProtKB: Q9Y468] There should be some charts here, you may need to enable JavaScript!
L3MBTL histone methyl-lysine binding protein 3/Lethal(3)malignant brain tumor-like protein 3 in Human [ChEMBL: CHEMBL1287623] [GtoPdb: 2830] [UniProtKB: Q96JM7] There should be some charts here, you may need to enable JavaScript!
Lethal(3)malignant brain tumor-like protein 4 in Human [ChEMBL: CHEMBL1287624] [UniProtKB: Q8NA19] There should be some charts here, you may need to enable JavaScript!
lysine demethylase 5A/Lysine-specific demethylase 5A in Human [ChEMBL: CHEMBL2424504] [GtoPdb: 2680] [UniProtKB: P29375] There should be some charts here, you may need to enable JavaScript!
MBT domain-containing protein 1 in Human [ChEMBL: CHEMBL1287625] [UniProtKB: Q05BQ5] There should be some charts here, you may need to enable JavaScript!
Mortality factor 4-like protein 1 in Human [ChEMBL: CHEMBL4630863] [UniProtKB: Q9UBU8] There should be some charts here, you may need to enable JavaScript!
M1 receptor/Muscarinic acetylcholine receptor M1 in Human [ChEMBL: CHEMBL216] [GtoPdb: 13] [UniProtKB: P11229] There should be some charts here, you may need to enable JavaScript!
M2 receptor/Muscarinic acetylcholine receptor M2 in Human [ChEMBL: CHEMBL211] [GtoPdb: 14] [UniProtKB: P08172] There should be some charts here, you may need to enable JavaScript!
M3 receptor/Muscarinic acetylcholine receptor M3 in Human [ChEMBL: CHEMBL245] [GtoPdb: 15] [UniProtKB: P20309] There should be some charts here, you may need to enable JavaScript!
M4 receptor/Muscarinic acetylcholine receptor M4 in Human [ChEMBL: CHEMBL1821] [GtoPdb: 16] [UniProtKB: P08173] There should be some charts here, you may need to enable JavaScript!
M5 receptor/Muscarinic acetylcholine receptor M5 in Human [ChEMBL: CHEMBL2035] [GtoPdb: 17] [UniProtKB: P08912] There should be some charts here, you may need to enable JavaScript!
PHD finger protein 20 in Human [ChEMBL: CHEMBL6067596] [UniProtKB: Q9BVI0] There should be some charts here, you may need to enable JavaScript!
PHD finger protein 20-like protein 1 in Human [ChEMBL: CHEMBL6066242] [UniProtKB: A8MW92] There should be some charts here, you may need to enable JavaScript!
PHD finger protein 23 in Human [ChEMBL: CHEMBL2424508] [UniProtKB: Q9BUL5] There should be some charts here, you may need to enable JavaScript!
Scm-like with four MBT domains protein 1 in Human [ChEMBL: CHEMBL1764944] [UniProtKB: Q9UHJ3] There should be some charts here, you may need to enable JavaScript!
DAT/Sodium-dependent dopamine transporter in Human [ChEMBL: CHEMBL238] [GtoPdb: 927] [UniProtKB: Q01959] There should be some charts here, you may need to enable JavaScript!
TP53-binding protein 1 in Human [ChEMBL: CHEMBL2424509] [UniProtKB: Q12888] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
α2C-adrenoceptor/Alpha-2C adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1916] [GtoPdb: 27] [UniProtKB: P18825]
ChEMBL	Selectivity interaction (NIMH Psychoactive Drug Screening Program Selectivity Panel (radioligand binding assay)) EUB0000214b ADRA2C	B	6.07	pKi	860	nM	Ki	Selectivity Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Inhibition of alpha2C receptor (unknown origin) by radioligand binding assay	B	6.07	pKi	860	nM	Ki	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
Chromobox protein homolog 7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1764946] [UniProtKB: O95931]
ChEMBL	Inhibition of CBX7 (8 to 62) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H3K9Me3 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay	B	4.52	pIC50	>30000	nM	IC50	Medchemcomm (2013) 4: 1501-1507 [PMID:24466405]
ChEMBL	Inhibition of chromo domain containing CBX7 (unknown origin) using H4K20me2 peptide by Alpha-Screen methylated histone peptide competition assay	B	4.52	pIC50	>30000	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Inhibition of CBX7 (unknown origin) after 30 mins by AlphaScreen assay	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
E3 ubiquitin-protein ligase UHRF1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2424510] [UniProtKB: Q96T88]
ChEMBL	Inhibition of UHRF1 tandem tudor domain (121 to 286) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H3K9Me3 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay	B	4.52	pIC50	>30000	nM	IC50	Medchemcomm (2013) 4: 1501-1507 [PMID:24466405]
ChEMBL	Inhibition of tudor domain containing UHRF1 (unknown origin) using H4K20me2 peptide by Alpha-Screen methylated histone peptide competition assay	B	4.52	pIC50	>30000	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Inhibition of UHRF1 (unknown origin) after 30 mins by AlphaScreen assay	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
κ receptor/Kappa-type opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145]
ChEMBL	Inhibition of KOR (unknown origin) by radioligand binding assay	B	5.4	pKi	4000	nM	Ki	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
Lethal(3)malignant brain tumor-like protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1287622] [UniProtKB: Q9Y468]
ChEMBL	Binding affinity to L3MBTL1 (unknown origin) by isothermal titration calorimetric assay	B	5.03	pKd	9400	nM	Kd	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
ChEMBL	Binding affinity to L3MBTL1 (unknown origin) by ITC assay	B	5.03	pKd	9400	nM	Kd	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Inhibition of His-tagged L3MBTL1 (unknown origin) using H4K20Me1 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay	B	5.05	pIC50	8900	nM	IC50	Medchemcomm (2013) 4: 1501-1507 [PMID:24466405]
ChEMBL	Inhibition of L3MBTL1 (unknown origin) after 30 mins by AlphaScreen assay	B	5.64	pIC50	2300	nM	IC50	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
ChEMBL	Selectivity interaction (AlphaScreen assay) EUB0000214b L3MBTL	B	5.7	pIC50	2000	nM	IC50	Selectivity Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Inhibition of MBT domain containing L3MBTL1 (unknown origin) using H4K20me2 peptide by Alpha-Screen methylated histone peptide competition assay	B	5.7	pIC50	2000	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
L3MBTL histone methyl-lysine binding protein 3/Lethal(3)malignant brain tumor-like protein 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1287623] [GtoPdb: 2830] [UniProtKB: Q96JM7]
GtoPdb	-	-	6.92	pKd	120	nM	Kd	Nat Chem Biol (2013) 9: 184-91 [PMID:23292653]
ChEMBL	Binding affinity to L3MBTL3 (unknown origin) by isothermal titration calorimetric assay	B	6.92	pKd	120	nM	Kd	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
ChEMBL	Inhibition of L3MBTL3 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry	B	6.92	pKd	120	nM	Kd	J Med Chem (2019) 62: 8996-9007 [PMID:31260300]
ChEMBL	Selectivity interaction (ITC) EUB0000214b L3MBTL3	B	6.92	pKd	120	nM	Kd	Selectivity Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Binding affinity to His-tagged wild type L3MBTL3 (unknown origin) assessed as dissociation constant by ITC analysis	B	6.92	pKd	120	nM	Kd	Eur J Med Chem (2023) 256: 115444-115444 [PMID:37178483]
ChEMBL	Binding affinity to L3MBTL3 (unknown origin) by ITC assay	B	6.92	pKd	120	nM	Kd	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Affinity Phenotypic Cellular interaction (Foci formation of GFP-3MBT in HEK293 cells) EUB0000214b L3MBTL3	F	6.3	pIC50	500	nM	IC50	Affinity Phenotypic Cellular Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Inhibition of GFP-3MBT tagged L3MBTL3 (unknown origin) expressed in HEK293 cells assessed as disruption of foci formation by immunofluorescence assay	B	6.3	pIC50	500	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay	B	7.19	pIC50	64	nM	IC50	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
ChEMBL	Inhibition of GFP-3MBT tagged L3MBTL3 (unknown origin) expressed in HEK293 cells assessed as reduction in recovery of fluorescence intensity measured up to 60 secs by FRAP assay	B	7.3	pIC50	50	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay	B	7.31	pIC50	49	nM	IC50	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
ChEMBL	Affinity Biochemical interaction (AlphaScreen assay) EUB0000214b L3MBTL3	B	7.4	pIC50	40	nM	IC50	Affinity Biochemical Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Inhibition of L3MBTL3 (unknown origin) using H4K20me2 peptide by Alpha-Screen methylated histone peptide competition assay	B	7.4	pIC50	40	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay	B	7.62	pIC50	24	nM	IC50	Medchemcomm (2013) 4: 1501-1507 [PMID:24466405]
Lethal(3)malignant brain tumor-like protein 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1287624] [UniProtKB: Q8NA19]
ChEMBL	Selectivity interaction (AlphaScreen assay) EUB0000214b L3MBTL4	B	4.96	pIC50	11000	nM	IC50	Selectivity Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Inhibition of MBT domain containing L3MBTL4 (unknown origin) using H4K20me2 peptide by Alpha-Screen methylated histone peptide competition assay	B	4.96	pIC50	11000	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Inhibition of L3MBTL4 (unknown origin) after 30 mins by AlphaScreen assay	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
lysine demethylase 5A/Lysine-specific demethylase 5A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2424504] [GtoPdb: 2680] [UniProtKB: P29375]
ChEMBL	Inhibition of GST-tagged Jarid1A (unknown origin) using H3K4Me3 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay	B	4.52	pIC50	>30000	nM	IC50	Medchemcomm (2013) 4: 1501-1507 [PMID:24466405]
ChEMBL	Inhibition of PHD finger domain containing JARID1A (unknown origin) using H4K20me2 peptide by Alpha-Screen methylated histone peptide competition assay	B	4.52	pIC50	>30000	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Inhibition of JARID1A (unknown origin) after 30 mins by AlphaScreen assay	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
MBT domain-containing protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1287625] [UniProtKB: Q05BQ5]
ChEMBL	Inhibition of MBTD1 (130 to 566) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H4K20Me1 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay	B	4.11	pIC50	78000	nM	IC50	Medchemcomm (2013) 4: 1501-1507 [PMID:24466405]
ChEMBL	Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assay	B	5.05	pIC50	9000	nM	IC50	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
ChEMBL	Selectivity interaction (AlphaScreen assay) EUB0000214b MBTD1	B	5.22	pIC50	6000	nM	IC50	Selectivity Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Inhibition of MBT domain containing MBTD1 (unknown origin) using H4K20me2 peptide by Alpha-Screen methylated histone peptide competition assay	B	5.22	pIC50	6000	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
Mortality factor 4-like protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4630863] [UniProtKB: Q9UBU8]
ChEMBL	Binding affinity to MRG15 (unknown origin) by ITC assay	B	4.54	pKd	28900	nM	Kd	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
M1 receptor/Muscarinic acetylcholine receptor M1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL216] [GtoPdb: 13] [UniProtKB: P11229]
ChEMBL	Antagonist activity at human M1 receptor assessed as reduction in acetylcholine-induced response by Schild analysis	F	5.65	pKd	2238.72	nM	Kd	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Selectivity interaction (NIMH Psychoactive Drug Screening Program Selectivity Panel (radioligand binding assay)) EUB0000214b CHRM1	B	7.01	pKi	97	nM	Ki	Selectivity Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Inhibition of M1 receptor (unknown origin) by radioligand binding assay	B	7.01	pKi	97	nM	Ki	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Inhibition of M1 receptor (unknown origin) by Ca2+ mobilization assay	F	5.44	pIC50	3600	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Antagonist activity at muscarinic M1 receptor (unknown origin) expressed in HEK293T cells assessed as inhibition of UNC1679 calcium mobilization	F	5.46	pIC50	3500	nM	IC50	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
M2 receptor/Muscarinic acetylcholine receptor M2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL211] [GtoPdb: 14] [UniProtKB: P08172]
ChEMBL	Antagonist activity at human M2 receptor assessed as reduction in acetylcholine-induced response by Schild analysis	F	7.61	pKd	24.55	nM	Kd	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Selectivity interaction (NIMH Psychoactive Drug Screening Program Selectivity Panel (radioligand binding assay)) EUB0000214b CHRM2	B	7.14	pKi	72	nM	Ki	Selectivity Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Inhibition of M2 receptor (unknown origin) by radioligand binding assay	B	7.14	pKi	72	nM	Ki	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
M3 receptor/Muscarinic acetylcholine receptor M3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL245] [GtoPdb: 15] [UniProtKB: P20309]
ChEMBL	Selectivity interaction (NIMH Psychoactive Drug Screening Program Selectivity Panel (radioligand binding assay)) EUB0000214b CHRM3	B	6.05	pKi	890	nM	Ki	Selectivity Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Inhibition of M3 receptor (unknown origin) by radioligand binding assay	B	6.05	pKi	890	nM	Ki	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
M4 receptor/Muscarinic acetylcholine receptor M4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1821] [GtoPdb: 16] [UniProtKB: P08173]
ChEMBL	Selectivity interaction (NIMH Psychoactive Drug Screening Program Selectivity Panel (radioligand binding assay)) EUB0000214b CHRM4	B	6.4	pKi	400	nM	Ki	Selectivity Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Inhibition of M4 receptor (unknown origin) by radioligand binding assay	B	6.4	pKi	400	nM	Ki	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
M5 receptor/Muscarinic acetylcholine receptor M5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2035] [GtoPdb: 17] [UniProtKB: P08912]
ChEMBL	Selectivity interaction (NIMH Psychoactive Drug Screening Program Selectivity Panel (radioligand binding assay)) EUB0000214b CHRM5	B	5.37	pKi	4300	nM	Ki	Selectivity Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Inhibition of M5 receptor (unknown origin) by radioligand binding assay	B	5.37	pKi	4300	nM	Ki	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
PHD finger protein 20 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6067596] [UniProtKB: Q9BVI0]
ChEMBL	Binding affinity to PHF20 (unknown origin) by ITC assay	B	5.25	pKd	5600	nM	Kd	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
PHD finger protein 20-like protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6066242] [UniProtKB: A8MW92]
ChEMBL	Binding affinity to tudor domain containing PHF20L1 (unknown origin) by ITC assay	B	4.89	pKd	>13000	nM	Kd	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
PHD finger protein 23 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2424508] [UniProtKB: Q9BUL5]
ChEMBL	Inhibition of GST-tagged PHF23 (unknown origin) using H3K4Me3 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay	B	4.52	pIC50	>30000	nM	IC50	Medchemcomm (2013) 4: 1501-1507 [PMID:24466405]
ChEMBL	Inhibition of PHD finger domain containing PHF23 (unknown origin) using H4K20me2 peptide by Alpha-Screen methylated histone peptide competition assay	B	4.52	pIC50	>30000	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Inhibition of PHF23 (unknown origin) after 30 mins by AlphaScreen assay	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
Scm-like with four MBT domains protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1764944] [UniProtKB: Q9UHJ3]
ChEMBL	Selectivity interaction (AlphaScreen assay) EUB0000214b SFMBT1	B	4.52	pIC50	>30000	nM	IC50	Selectivity Literature for EUbOPEN Chemogenomics Library wave 3
ChEMBL	Inhibition of MBT domain containing SFMBT (unknown origin) using H4K20me2 peptide by Alpha-Screen methylated histone peptide competition assay	B	4.52	pIC50	>30000	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Inhibition of SFMBT1 (unknown origin) after 30 mins by AlphaScreen assay	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
DAT/Sodium-dependent dopamine transporter in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL238] [GtoPdb: 927] [UniProtKB: Q01959]
ChEMBL	Inhibition of DAT (unknown origin) by radioligand binding assay	B	5	pKi	>10000	nM	Ki	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
TP53-binding protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2424509] [UniProtKB: Q12888]
ChEMBL	Binding affinity to 53BP1 (unknown origin) by ITC assay	B	4.51	pKd	>31000	nM	Kd	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]
ChEMBL	Inhibition of 53BP1 (1485 to 1611) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay	B	4.86	pIC50	13700	nM	IC50	Medchemcomm (2013) 4: 1501-1507 [PMID:24466405]
ChEMBL	Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assay	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 7358-7371 [PMID:24040942]
ChEMBL	Inhibition of tudor domain containing 53BP1 (unknown origin) using H4K20me2 peptide by Alpha-Screen methylated histone peptide competition assay	B	5.4	pIC50	4000	nM	IC50	Nat Chem Biol (2013) 9: 184-191 [PMID:23292653]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]