PAF [Ligand Id: 1831] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1235246 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| PAF receptor/Platelet activating factor receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL250] [GtoPdb: 334] [UniProtKB: P25105] | ||||||||
| GtoPdb | - | - | 7.9 | pKi | - | - | - |
J Biol Chem (1991) 266: 20400-5 [PMID:1657923]; J Biol Chem (1996) 271: 23298-303 [PMID:8798529] |
| ChEMBL | Displacement of [3H]PAF from platelet activating factor receptor in human platelets after 3 hrs | B | 9.82 | pKi | 0.15 | nM | Ki | Bioorg Med Chem Lett (2013) 23: 1834-1838 [PMID:23403082] |
| GtoPdb | - | - | 8.2 | pIC50 | - | - | - | J Immunol Methods (1995) 186: 225-31 [PMID:7594622] |
| ChEMBL | Displacement of [3H]PAF from platelet activating factor receptor in human platelets after 3 hrs | B | 9.55 | pIC50 | 0.28 | nM | IC50 | Bioorg Med Chem Lett (2013) 23: 1834-1838 [PMID:23403082] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
