1. Abdulla MH, Sattar MA, Johns EJ, Abdullah NA, Hye Khan MA, Rathore HA. (2012) High-fructose feeding impacts on the adrenergic control of renal haemodynamics in the rat.
Br J Nutr, 107 (2): 218-28.
[PMID:21733307]
2. Aizawa N, Sugiyama R, Ichihara K, Fujimura T, Fukuhara H, Homma Y, Igawa Y. (2016) Functional roles of bladder α1-adrenoceptors in the activation of single-unit primary bladder afferent activity in rats.
BJU Int, 117 (6): 993-1001.
[PMID:26332379]
3. Alonso-Llamazares A, Zamanillo D, Casanova E, Ovalle S, Calvo P, Chinchetru MA. (1995) Molecular cloning of alpha 1d-adrenergic receptor and tissue distribution of three alpha 1-adrenergic receptor subtypes in mouse.
J Neurochem, 65: 2387-2392.
[PMID:7595531]
4. Aono Y, Taguchi H, Saigusa T, Uchida T, Takada K, Takiguchi H, Shirakawa T, Shimizu N, Koshikawa N, Cools AR. (2015) Simultaneous activation of the α1A-, α1B- and α1D-adrenoceptor subtypes in the nucleus accumbens reduces accumbal dopamine efflux in freely moving rats.
Behav Pharmacol, 26 (1-2): 73-80.
[PMID:25438092]
5. Armenia, Sattar MA, Abdullah NA, Khan MA, Johns EJ. (2008) Alpha1A- and alpha1D-adrenoceptors are the major functional subtypes of renal alpha1-adrenoceptors in streptozotocin-induced diabetic and normal Sprague-Dawley rats.
Auton Autacoid Pharmacol, 28 (1): 1-10.
[PMID:18257746]
6. Arévalo-León LE, Gallardo-Ortíz IA, Urquiza-Marín H, Villalobos-Molina R. (2003) Evidence for the role of alpha1D- and alpha1A-adrenoceptors in contraction of the rat mesenteric artery.
Vascul Pharmacol, 40 (2): 91-6.
[PMID:12646397]
7. Auerbach SS, DrugMatrix® and ToxFX® Coordinator National Toxicology Program. National Toxicology Program: Dept of Health and Human Services.
Accessed on 02/05/2014. Modified on 02/05/2014.
DrugMatrix, https://ntp.niehs.nih.gov/drugmatrix/index.html
8. Bruno JF, Whittaker J, Song JF, Berelowitz M. (1991) Molecular cloning and sequencing of a cDNA encoding a human alpha 1A adrenergic receptor.
Biochem Biophys Res Commun, 179 (3): 1485-90.
[PMID:1656955]
9. Carmona-Rosas G, Hernández-Espinosa DA, Alcántara-Hernández R, Alfonzo-Méndez MA, García-Sainz JA. (2019) Distinct phosphorylation sites/clusters in the carboxyl terminus regulate α1D-adrenergic receptor subcellular localization and signaling.
Cell Signal, 53: 374-389.
[PMID:30419287]
10. Carroll WA, Sippy KB, Esbenshade TA, Buckner SA, Hancock AA, Meyer MD. (2001) Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien.
Bioorg Med Chem Lett, 11 (9): 1119-21.
[PMID:11354357]
11. Chalothorn D, McCune DF, Edelmann SE, Tobita K, Keller BB, Lasley RD, Perez DM, Tanoue A, Tsujimoto G, Post GR et al.. (2003) Differential cardiovascular regulatory activities of the alpha 1B- and alpha 1D-adrenoceptor subtypes.
J Pharmacol Exp Ther, 305 (3): 1045-53.
[PMID:12649302]
12. Chen L, Hodges RR, Funaki C, Zoukhri D, Gaivin RJ, Perez DM, Dartt DA. (2006) Effects of alpha1D-adrenergic receptors on shedding of biologically active EGF in freshly isolated lacrimal gland epithelial cells.
Am J Physiol, Cell Physiol, 291 (5): C946-56.
[PMID:16760267]
13. Chen Q, Takahashi S, Zhong S, Hosoda C, Zheng HY, Ogushi T, Fujimura T, Ohta N, Tanoue A, Tsujimoto G et al.. (2005) Function of the lower urinary tract in mice lacking alpha1d-adrenoceptor.
J Urol, 174 (1): 370-4.
[PMID:15947692]
14. Chen Z, Hague C, Hall RA, Minneman KP. (2006) Syntrophins regulate alpha1D-adrenergic receptors through a PDZ domain-mediated interaction.
J Biol Chem, 281 (18): 12414-20.
[PMID:16533813]
15. Chiba S, Tsukada M. (2002) Existence of functional alpha1A- and alpha1D- but no alpha1B-adrenoceptor subtypes in rat common carotid arteries.
Jpn J Pharmacol, 88 (2): 146-50.
[PMID:11928714]
16. Cohn HI, Harris DM, Pesant S, Pfeiffer M, Zhou RH, Koch WJ, Dorn GW, Eckhart AD. (2008) Inhibition of vascular smooth muscle G protein-coupled receptor kinase 2 enhances alpha1D-adrenergic receptor constriction.
Am J Physiol Heart Circ Physiol, 295 (4): H1695-704.
[PMID:18723764]
17. Conley RK, Williams TJ, Ford AP, Ramage AG. (2001) The role of alpha(1)-adrenoceptors and 5-HT(1A) receptors in the control of the micturition reflex in male anaesthetized rats.
Br J Pharmacol, 133 (1): 61-72.
[PMID:11325795]
18. da Silva ES, Flores RA, Cella EC, Levone BR, Taschetto AP, Kochenborger L, Terenzi MG, Faria MS, Paschoalini MA. (2014) Blockade of median raphe nucleus α1-adrenoceptor subtypes increases food intake in rats.
Pharmacol Biochem Behav, 124: 350-5.
[PMID:24955865]
19. da Silva Junior ED, Sato M, Merlin J, Broxton N, Hutchinson DS, Ventura S, Evans BA, Summers RJ. (2017) Factors influencing biased agonism in recombinant cells expressing the human α1A -adrenoceptor.
Br J Pharmacol, 174 (14): 2318-2333.
[PMID:28444738]
20. Dartt DA, Hodges RR. (2011) Interaction of alpha1D-adrenergic and P2X(7) receptors in the rat lacrimal gland and the effect on intracellular [Ca2+] and protein secretion.
Invest Ophthalmol Vis Sci, 52 (8): 5720-9.
[PMID:21685341]
21. Day HE, Kryskow EM, Watson SJ, Akil H, Campeau S. (2008) Regulation of hippocampal alpha1d adrenergic receptor mRNA by corticosterone in adrenalectomized rats.
Brain Res, 1218: 132-40.
[PMID:18534559]
22. de Andrade CR, Fukada SY, Olivon VC, de Godoy MA, Haddad R, Eberlin MN, Cunha FQ, de Souza HP, Laurindo FR, de Oliveira AM. (2006) Alpha1D-adrenoceptor-induced relaxation on rat carotid artery is impaired during the endothelial dysfunction evoked in the early stages of hyperhomocysteinemia.
Eur J Pharmacol, 543 (1-3): 83-91.
[PMID:16828078]
23. Docherty JR. (2011) Vasopressor nerve responses in the pithed rat, previously identified as α2-adrenoceptor mediated, may be α1D-adrenoceptor mediated.
Eur J Pharmacol, 658 (2-3): 182-6.
[PMID:21376031]
24. Docherty JR. (2012) Yohimbine antagonises α1A- and α1D-adrenoceptor mediated components in addition to the α2A-adrenoceptor component to pressor responses in the pithed rat.
Eur J Pharmacol, 679 (1-3): 90-4.
[PMID:22290390]
25. Filippi S, Parenti A, Donnini S, Granger HJ, Fazzini A, Ledda F. (2001) alpha(1D)-adrenoceptors cause endothelium-dependent vasodilatation in the rat mesenteric vascular bed.
J Pharmacol Exp Ther, 296 (3): 869-75.
[PMID:11181918]
26. Flacco N, Parés J, Serna E, Segura V, Vicente D, Pérez-Aso M, Noguera MA, Ivorra MD, McGrath JC, D'Ocon P. (2013) α1D-Adrenoceptors are responsible for the high sensitivity and the slow time-course of noradrenaline-mediated contraction in conductance arteries.
Pharmacol Res Perspect, 1 (1): e00001.
[PMID:25505555]
27. Ford AP, Daniels DV, Chang DJ, Gever JR, Jasper JR, Lesnick JD, Clarke DE. (1997) Pharmacological pleiotropism of the human recombinant alpha1A-adrenoceptor: implications for alpha1-adrenoceptor classification.
Br J Pharmacol, 121 (6): 1127-35.
[PMID:9249248]
28. García-Cazarín ML, Smith JL, Clair DK, Piascik MT. (2008) The alpha1D-adrenergic receptor induces vascular smooth muscle apoptosis via a p53-dependent mechanism.
Mol Pharmacol, 74 (4): 1000-7.
[PMID:18628404]
29. García-Cazarín ML, Smith JL, Olszewski KA, McCune DF, Simmerman LA, Hadley RW, Kraner SD, Piascik MT. (2008) The alpha1D-adrenergic receptor is expressed intracellularly and coupled to increases in intracellular calcium and reactive oxygen species in human aortic smooth muscle cells.
J Mol Signal, 3: 6.
[PMID:18304336]
30. García-Sáinz JA, Rodríguez-Pérez CE, Romero-Avila MT. (2004) Human alpha1D-adrenoceptor phosphorylation and desensitization.
Biochem Pharmacol, 67 (10): 1853-8.
[PMID:15130762]
31. García-Sáinz JA, Vázquez-Cuevas FG, Romero-Avila MT. (2001) Phosphorylation and desensitization of alpha1d-adrenergic receptors.
Biochem J, 353 (Pt 3): 603-10.
[PMID:11171057]
32. Giardinà D, Crucianelli M, Romanelli R, Leonardi A, Poggesi E, Melchiorre C. (1996) Synthesis and biological profile of the enantiomers of [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-cis-octahydroquinoxalin- 1-yl]furan-2-ylmethanone (cyclazosin), a potent competitive alpha 1B- adrenoceptor antagonist.
J Med Chem, 39 (23): 4602-7.
[PMID:8917649]
33. González-Hernández Mde L, Godínez-Hernández D, Bobadilla-Lugo RA, López-Sánchez P. (2010) Angiotensin-II type 1 receptor (AT1R) and alpha-1D adrenoceptor form a heterodimer during pregnancy-induced hypertension.
Auton Autacoid Pharmacol, 30 (3): 167-72.
[PMID:20102360]
34. Greuel JM, Glaser T. (1992) The putative 5-HT1A receptor antagonists NAN-190 and BMY 7378 are partial agonists in the rat dorsal raphe nucleus in vitro.
Eur J Pharmacol, 211 (2): 211-9.
[PMID:1535319]
35. Hague C, Chen Z, Uberti M, Minneman KP. (2003) Alpha(1)-adrenergic receptor subtypes: non-identical triplets with different dancing partners?.
Life Sci, 74 (4): 411-8.
[PMID:14609720]
36. Hague C, Lee SE, Chen Z, Prinster SC, Hall RA, Minneman KP. (2006) Heterodimers of alpha1B- and alpha1D-adrenergic receptors form a single functional entity.
Mol Pharmacol, 69 (1): 45-55.
[PMID:16195468]
37. Hague C, Uberti MA, Chen Z, Hall RA, Minneman KP. (2004) Cell surface expression of alpha1D-adrenergic receptors is controlled by heterodimerization with alpha1B-adrenergic receptors.
J Biol Chem, 279 (15): 15541-9.
[PMID:14736874]
38. Hampel C, Dolber PC, Smith MP, Savic SL, Th roff JW, Thor KB, Schwinn DA. (2002) Modulation of bladder alpha1-adrenergic receptor subtype expression by bladder outlet obstruction.
J Urol, 167 (3): 1513-21.
[PMID:11832780]
39. Hancock AA, Buckner SA, Brune ME, Katwala S, Milicic I, Ireland LM, Morse PA, Knepper SM, Meyer MD,Chapple CR et al.. (1998) Pharmacological characterization of A-131701, a novel R 1 -adrenoceptor antagonist selective for R 1A - and R 1D - compared to R 1B -adrenoceptors.
Drug Development Research, 44: 140-162.
40. Harasawa I, Honda K, Tanoue A, Shinoura H, Ishida Y, Okamura H, Murao N, Tsujimoto G, Higa K, Kamiya HO et al.. (2003) Responses to noxious stimuli in mice lacking alpha(1d)-adrenergic receptors.
Neuroreport, 14 (14): 1857-60.
[PMID:14534435]
41. Hieble JP. (2000) Adrenoceptor subclassification: an approach to improved cardiovascular therapeutics.
Pharm Acta Helv, 74 (2-3): 163-71.
[PMID:10812954]
42. Hieble JP, Bylund DB, Clarke DE, Eikenburg DC, Langer SZ, Lefkowitz RJ, Minneman KP, Ruffolo Jr RR. (1995) International Union of Pharmacology. X. Recommendation for nomenclature of alpha 1-adrenoceptors: consensus update.
Pharmacol Rev, 47 (2): 267-70.
[PMID:7568329]
43. Hieble JP, Ruffolo Jr RR. (1996) Subclassification and nomenclature of alpha 1- and alpha 2-adrenoceptors.
Prog Drug Res, 47: 81-130.
[PMID:8961765]
44. Hodges RR, Shatos MA, Tarko RS, Vrouvlianis J, Gu J, Dartt DA. (2005) Nitric oxide and cGMP mediate alpha1D-adrenergic receptor-Stimulated protein secretion and p42/p44 MAPK activation in rat lacrimal gland.
Invest Ophthalmol Vis Sci, 46 (8): 2781-9.
[PMID:16043851]
45. Horie K, Obika K, Foglar R, Tsujimoto G. (1995) Selectivity of the imidazoline alpha-adrenoceptor agonists (oxymetazoline and cirazoline) for human cloned alpha 1-adrenoceptor subtypes.
Br J Pharmacol, 116 (1): 1611-8.
[PMID:8564227]
46. Hosoda C, Koshimizu TA, Tanoue A, Nasa Y, Oikawa R, Tomabechi T, Fukuda S, Shinoura H, Oshikawa S, Takeo S et al.. (2005) Two alpha1-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation.
Mol Pharmacol, 67 (3): 912-22.
[PMID:15598970]
47. Hrometz SL, Edelmann SE, McCune DF, Olges JR, Hadley RW, Perez DM, Piascik MT. (1999) Expression of multiple alpha1-adrenoceptors on vascular smooth muscle: correlation with the regulation of contraction.
J Pharmacol Exp Ther, 290 (1): 452-63.
[PMID:10381812]
48. Huo S, Zhong X, Wu X, Li Y. (2012) Effects of norepinephrine and acetylcholine on the development of cultured Leydig cells in mice.
J Biomed Biotechnol, 2012: 503093.
[PMID:23093848]
49. Ishihama H, Momota Y, Yanase H, Wang X, de Groat WC, Kawatani M. (2006) Activation of alpha1D adrenergic receptors in the rat urothelium facilitates the micturition reflex.
J Urol, 175 (1): 358-64.
[PMID:16406942]
50. Janezic EM, Harris DA, Dinh D, Lee KS, Stewart A, Hinds TR, Hsu PL, Zheng N, Hague C. (2019) Scribble co-operatively binds multiple α1D-adrenergic receptor C-terminal PDZ ligands.
Sci Rep, 9 (1): 14073.
[PMID:31575922]
51. Janezic EM, Lauer SM, Williams RG, Chungyoun M, Lee KS, Navaluna E, Lau HT, Ong SE, Hague C. (2020) N-glycosylation of α1D-adrenergic receptor N-terminal domain is required for correct trafficking, function, and biogenesis.
Sci Rep, 10 (1): 7209.
[PMID:32350295]
52. Jensen BC, Swigart PM, Laden ME, DeMarco T, Hoopes C, Simpson PC. (2009) The alpha-1D Is the predominant alpha-1-adrenergic receptor subtype in human epicardial coronary arteries.
J Am Coll Cardiol, 54 (13): 1137-45.
[PMID:19761933]
53. Kandasamy K, Choudhury S, Singh V, Addison MP, Darzi SA, Kasa JK, Thangamalai R, Dash JR, Kumar T, Sultan F et al.. (2016) Erythropoietin Reverses Sepsis-Induced Vasoplegia to Norepinephrine Through Preservation of α1D-Adrenoceptor mRNA Expression and Inhibition of GRK2-Mediated Desensitization in Mouse Aorta.
J Cardiovasc Pharmacol Ther, 21 (1): 100-13.
[PMID:26025460]
54. Khattar SK, Bora RS, Priyadarsiny P, Gautam A, Gupta D, Tiwari A, Nanda K, Singh R, Chugh A, Bansal V et al.. (2006) Molecular cloning, stable expression and cellular localization of human alpha1-adrenergic receptor subtypes: effect of charcoal/dextran treated serum on expression and localization of alpha1D -adrenergic receptor.
Biotechnol Lett, 28 (21): 1731-9.
[PMID:16912925]
55. Kojima Y, Sasaki S, Kubota Y, Hayase M, Hayashi Y, Shinoura H, Tsujimoto G, Kohri K. (2008) Expression of alpha1-adrenoceptor subtype mRNA as a predictor of the efficacy of subtype selective alpha1-adrenoceptor antagonists in the management of benign prostatic hyperplasia.
J Urol, 179 (3): 1040-6.
[PMID:18206918]
56. Kojima Y, Sasaki S, Kubota Y, Imura M, Oda N, Kiniwa M, Hayashi Y, Kohri K. (2011) Up-regulation of α1a and α1d-adrenoceptors in the prostate by administration of subtype selective α1-adrenoceptor antagonist tamsulosin in patients with benign prostatic hyperplasia.
J Urol, 186 (4): 1530-6.
[PMID:21855934]
57. Koshimizu TA, Tanoue A, Hirasawa A, Yamauchi J, Tsujimoto G. (2003) Recent advances in alpha1-adrenoceptor pharmacology.
Pharmacol Ther, 98 (2): 235-44.
[PMID:12725871]
58. Koshimizu TA, Tsujimoto G, Hirasawa A, Kitagawa Y, Tanoue A. (2004) Carvedilol selectively inhibits oscillatory intracellular calcium changes evoked by human alpha1D- and alpha1B-adrenergic receptors.
Cardiovasc Res, 63 (4): 662-72.
[PMID:15306222]
59. Kountz TS, Lee KS, Aggarwal-Howarth S, Curran E, Park JM, Harris DA, Stewart A, Hendrickson J, Camp ND, Wolf-Yadlin A et al.. (2016) Endogenous N-terminal Domain Cleavage Modulates α1D-Adrenergic Receptor Pharmacodynamics.
J Biol Chem, 291 (35): 18210-21.
[PMID:27382054]
60. Leech CJ, Faber JE. (1996) Different alpha-adrenoceptor subtypes mediate constriction of arterioles and venules.
Am J Physiol, 270 (2 Pt 2): H710-22.
[PMID:8779849]
61. Liu CM, Lo YC, Wu BN, Wu WJ, Chou YH, Huang CH, An LM, Chen IJ. (2007) cGMP-enhancing- and alpha1A/alpha1D-adrenoceptor blockade-derived inhibition of Rho-kinase by KMUP-1 provides optimal prostate relaxation and epithelial cell anti-proliferation efficacy.
Prostate, 67 (13): 1397-410.
[PMID:17639498]
62. Liu R, Zhang Q, Luo Q, Qiao H, Wang P, Yu J, Cao Y, Lu B, Qu L. (2017) Norepinephrine stimulation of alpha1D-adrenoceptor promotes proliferation of pulmonary artery smooth muscle cells via ERK-1/2 signaling.
Int J Biochem Cell Biol, 88: 100-112.
[PMID:28476501]
63. Lomasney JW, Cotecchia S, Lorenz W, Leung WY, Schwinn DA, Yang-Feng TL, Brownstein M, Lefkowitz RJ, Caron MG. (1991) Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5.
J Biol Chem, 266 (10): 6365-9.
[PMID:1706716]
64. Lyssand JS, DeFino MC, Tang XB, Hertz AL, Feller DB, Wacker JL, Adams ME, Hague C. (2008) Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.
J Biol Chem, 283 (27): 18792-800.
[PMID:18468998]
65. Lyssand JS, Lee KS, DeFino M, Adams ME, Hague C. (2011) Syntrophin isoforms play specific functional roles in the α1D-adrenergic receptor/DAPC signalosome.
Biochem Biophys Res Commun, 412 (4): 596-601.
[PMID:21846462]
66. Lyssand JS, Whiting JL, Lee KS, Kastl R, Wacker JL, Bruchas MR, Miyatake M, Langeberg LK, Chavkin C, Scott JD et al.. (2010) Alpha-dystrobrevin-1 recruits alpha-catulin to the alpha1D-adrenergic receptor/dystrophin-associated protein complex signalosome.
Proc Natl Acad Sci USA, 107 (50): 21854-9.
[PMID:21115837]
67. Malloy BJ, Price DT, Price RR, Bienstock AM, Dole MK, Funk BL, Rudner XL, Richardson CD, Donatucci CF, Schwinn DA. (1998) Alpha1-adrenergic receptor subtypes in human detrusor.
J Urol, 160 (3 Pt 1): 937-43.
[PMID:9720591]
68. Methven L, Simpson PC, McGrath JC. (2009) Alpha1A/B-knockout mice explain the native alpha1D-adrenoceptor's role in vasoconstriction and show that its location is independent of the other alpha1-subtypes.
Br J Pharmacol, 158 (7): 1663-75.
[PMID:19888965]
69. Meyer MD, Altenbach RJ, Basha FZ, Carroll WA, Drizin I, Elmore SW, Ehrlich PP, Lebold SA, Tietje K, Sippy KB et al.. (1997) Synthesis and pharmacological characterization of 3-[2-((3aR,9bR)-cis-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[e] isoindol-2-yl)ethyl]pyrido-[3',4':4,5]thieno[3,2-d]pyrimidine-2,4 (1H,3H)-dione (A-131701): a uroselective alpha 1A adrenoceptor antagonist for the symptomatic treatment of benign prostatic hyperplasia.
J Med Chem, 40 (20): 3141-3.
[PMID:9379432]
70. Michelotti GA, Brinkley DM, Morris DP, Smith MP, Louie RJ, Schwinn DA. (2007) Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation.
FASEB J, 21 (9): 1979-93.
[PMID:17384146]
71. Michelotti GA, Price DT, Schwinn DA. (2000) Alpha 1-adrenergic receptor regulation: basic science and clinical implications.
Pharmacol Ther, 88 (3): 281-309.
[PMID:11337028]
72. Minarini A, Budriesi R, Chiarini A, Leonardi A, Melchiorre C. (1998) Search for alpha 1-adrenoceptor subtypes selective antagonists: design, synthesis and biological activity of cystazosin, an alpha 1D-adrenoceptor antagonist.
Bioorg Med Chem Lett, 8 (11): 1353-8.
[PMID: