adropin   Click here for help

GtoPdb Ligand ID: 9573

Compound class: Endogenous peptide in human, mouse or rat
Comment: Adropin is a peptide hormone translated form he EHNO gene [2]. Its biological function is poorly understood, but it was originally suggested to be linked to energy homeostasis and lipid metabolism [1-3].
Adropin has been suggested as an endogenous ligand for the orphan GPCR, GPR19 [4-5], although de-orphanisation requires further confirmatory evidence.
The amino acid sequence of this protein in humans, mice and rats is identical.
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
ENHO energy homeostasis associated Human adropin -
Database Links Click here for help
Specialist databases
GPCRdb Ligand adropin
Other databases
Ensembl Gene ENSG00000168913 (Hs)
Entrez Gene 375704 (Hs)
GtoPdb PubChem SID 336446959
Human Protein Atlas ENSG00000168913 (Hs)
RefSeq Nucleotide NM_198573 (Hs)
RefSeq Protein NP_940975 (Hs)
UniProtKB Q6UWT2 (Hs)