danaparoid   Click here for help

GtoPdb Ligand ID: 6804

Synonyms: ORG-10172 | Orgaran®
Approved drug
danaparoid is an approved drug (FDA (1996), still marketed outside the U.S.)
Compound class: Synthetic organic
Comment: Danaparoid sodium is an anticoagulant that works by inhibiting activated factor X. It is no longer marketed in the US but is still available in other countries. As this drug is a mixture of components (heparan sulfate, dermatan sulfate, and chondroitin sulfate) we are unable to give structural information.
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Summary of Clinical Use Click here for help
Used as a prophylaxis for deep-vein thrombosis in high-risk conditions.
Mechanism Of Action and Pharmacodynamic Effects Click here for help
A heparinoid with little cross-reactivity in heparin-intolerant patients. It consists of a mixture of heparan sulfate, dermatan sulfate, and chondroitin sulfate.