Synonyms: 2-sulfanilamido-4-methylpyrimidine | sulfamethyldiazine | sulphamerazine
sulfamerazine is an approved drug (FDA (1949))
Compound class:
Synthetic organic
Comment: Sulfamerazine is a sulfonamide antibacterial compound [4]. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth.
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Classification | |
Compound class | Synthetic organic |
Approved drug? | Yes (FDA (1949)) |
IUPAC Name |
4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide |
International Nonproprietary Names | |
INN number | INN |
424 | sulfamerazine |
Synonyms |
2-sulfanilamido-4-methylpyrimidine | sulfamethyldiazine | sulphamerazine |
Database Links | |
Specialist databases | |
Antibiotic DB | Sulfamerazine |
Other databases | |
CAS Registry No. | 127-79-7 (source: Scifinder) |
ChEBI | CHEBI:102130 |
ChEMBL Ligand | CHEMBL438 |
DrugBank Ligand | DB01581 |
DrugCentral Ligand | 2510 |
GtoPdb PubChem SID | 479821430 |
PubChem CID | 5325 |
Search Google for chemical match using the InChIKey | QPPBRPIAZZHUNT-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | QPPBRPIAZZHUNT |
Search PubMed clinical trials | sulfamerazine |
Search PubMed titles | sulfamerazine |
Search PubMed titles/abstracts | sulfamerazine |
UniChem Compound Search for chemical match using the InChIKey | QPPBRPIAZZHUNT-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | QPPBRPIAZZHUNT-UHFFFAOYSA-N |