Synonyms: EGIS11150 | S 36549 | S-36549 | S36549
Compound class:
Synthetic organic
Comment: EGIS-11150 is an antipsychotic compound that has demonstrated procognitive efficacy in preclinical models [1-2]. It has an 'atypical' antipsychotic drug profile, with effects on several GPCR receptor pathways within the hippocampal-prefrontal cortex circuit. It has been proposed as a modulator of psychosis and cognitive dysfunction in schizophrenia [2].
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Classification | |
Compound class | Synthetic organic |
Synonyms |
EGIS11150 | S 36549 | S-36549 | S36549 |
Database Links | |
Specialist databases | |
GPCRdb Ligand | EGIS-11150 |
Other databases | |
CAS Registry No. | 494861-87-9 (source: PubChem) |
GtoPdb PubChem SID | 464244100 |
PubChem CID | 9909267 |
Search Google for chemical match using the InChIKey | BQNLTXZVZWVEDX-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | BQNLTXZVZWVEDX |
UniChem Compound Search for chemical match using the InChIKey | BQNLTXZVZWVEDX-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | BQNLTXZVZWVEDX-UHFFFAOYSA-N |