Synonyms: ORM10962
Compound class:
Synthetic organic
Comment: ORM-10962 is a selective inhibitor of the SCL8 (NCX) Na+/Ca2+ exchangers [1]. It blocks both inward and outward NCX currents. ORM-10962 has been used in vivo to demonstrate that NCX blockade may contribute to the prevention of delayed afterdepolarization-based arrhythmogenesis.
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
2-(4-hydroxypiperidin-1-yl)-N-[6-[(2-phenyl-3,4-dihydro-2H-chromen-6-yl)oxy]pyridin-3-yl]acetamide |
Synonyms |
ORM10962 |
Database Links | |
GtoPdb PubChem SID | 434122221 |
PubChem CID | 69016811 |
Search Google for chemical match using the InChIKey | UPGUBLDTYLMRHO-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | UPGUBLDTYLMRHO |
UniChem Compound Search for chemical match using the InChIKey | UPGUBLDTYLMRHO-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | UPGUBLDTYLMRHO-UHFFFAOYSA-N |